Gene: ITGB3 (integrin subunit beta 3) Homo sapiens
Symbol: ITGB3
Name: integrin subunit beta 3
Description: The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BDPLT16; BDPLT2; CD61; GP3A; GPIIIa; GT; integrin beta 3; integrin beta-3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); platelet glycoprotein IIIa; platelet membrane glycoprotein IIIa
Latest Assembly: Human Genome Assembly GRCh37
Human Genome Assembly GRCh381747,253,842 - 47,312,711+NCBI
Human Alternate Assembly CHM1_11745,396,156 - 45,455,032+NCBI
Human Genome Assembly HuRef1740,709,287 - 40,768,167+NCBI
Human Genome Assembly GRCh371745,331,208 - 45,390,077+NCBI
Human Celera Assembly1741,781,276 - 41,840,192+NCBI
Human Genome Assembly Build 361742,686,207 - 42,745,076+NCBI
Human Cytogenetic Map17q21.32 NCBI
Human Genome Assembly1742,686,206 - 42,745,076 NCBI

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)
Launch JBrowse : build 36 (hg18) build 37 (hg19)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ITGB3
Entrez Gene
Ensembl Gene
GBrowse: hg18 hg19
JBrowse: hg18 hg19
HGNC Report
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1345363
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2016-02-02
Status: ACTIVE