Gene: KRT5 (keratin 5) Homo sapiens
Symbol: KRT5
Name: keratin 5
Description: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 58 kda cytokeratin; CK-5; CK5; cytokeratin-5; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin, type II cytoskeletal 5; KRT5A; OTTHUMP00000241816; type-II keratin Kb5
Orthologs:
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381252,514,575 - 52,520,459 (-)NCBIGRCh38hg38GRCh38
GRCh371252,908,359 - 52,914,328 (-)NCBIGRCh37hg19GRCh37
Build 361251,194,626 - 51,200,510 (-)NCBINCBI36hg18NCBI36
Build 341251,194,627 - 51,200,510NCBI
Celera1252,554,605 - 52,560,489 (-)NCBI
Cytogenetic Map12q13.13NCBImapview
HuRef1249,952,275 - 49,958,159 (-)NCBI
CHM1_11252,875,216 - 52,881,100 (-)NCBI
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KRT5
Entrez Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1343872
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2016-07-19
Status: ACTIVE