Gene: KRT5 (keratin 5) Homo sapiens
Symbol: KRT5
Name: keratin 5
Description: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 58 kda cytokeratin; CK-5; CK5; cytokeratin-5; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin, type II cytoskeletal 5; KRT5A; OTTHUMP00000241816; type-II keratin Kb5
Orthologs:
Mus musculus : Krt5 (keratin 5)  MGI
Rattus norvegicus : Krt5 (keratin 5)
more info ...
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Genome Assembly GRCh381252,514,575 - 52,520,459-NCBI
Human Alternate Assembly CHM1_11252,875,216 - 52,881,100-NCBI
Human Genome Assembly HuRef1249,952,275 - 49,958,159-NCBI
Human Genome Assembly GRCh371252,908,359 - 52,914,328-NCBI
Human Celera Assembly1252,554,605 - 52,560,489-NCBI
Human Genome Assembly Build 361251,194,626 - 51,200,510-NCBI
Human Cytogenetic Map12q13.13 NCBI
Human Genome Assembly1251,194,627 - 51,200,510 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KRT5
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1343872
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2014-10-15
Status: ACTIVE