Gene: KRT5 (keratin 5, type II) Homo sapiens
Symbol: KRT5
Name: keratin 5, type II
Description: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 58 kda cytokeratin; CK-5; CK5; cytokeratin-5; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin, type II cytoskeletal 5; KRT5A; OTTHUMP00000241816; type-II keratin Kb5
Mus musculus : Krt5 (keratin 5)  MGI
Rattus norvegicus : Krt5 (keratin 5, type II)
more info ...
Latest Assembly: Human Genome Assembly GRCh37
Human Genome Assembly GRCh381252,514,575 - 52,520,459-NCBI
Human Alternate Assembly CHM1_11252,875,216 - 52,881,100-NCBI
Human Genome Assembly HuRef1249,952,275 - 49,958,159-NCBI
Human Genome Assembly GRCh371252,908,359 - 52,914,328-NCBI
Human Celera Assembly1252,554,605 - 52,560,489-NCBI
Human Genome Assembly Build 361251,194,626 - 51,200,510-NCBI
Human Cytogenetic Map12q13.13 NCBI
Human Genome Assembly1251,194,627 - 51,200,510 NCBI

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)
Launch JBrowse : build 36 (hg18) build 37 (hg19)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KRT5
Entrez Gene
Ensembl Gene
GBrowse: hg18 hg19
JBrowse: hg18 hg19
HGNC Report
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1343872
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2016-01-26
Status: ACTIVE