Gene: RAB5A (RAB5A, member RAS oncogene family) Homo sapiens
Symbol: RAB5A
Name: RAB5A, member RAS oncogene family
Description: ENCODES a protein that exhibits GDP binding; GTP binding; GTPase activity; INVOLVED IN early endosome to late endosome transport; endocytosis; positive regulation of exocytosis; PARTICIPATES IN platelet-derived growth factor signaling pathway; amyotrophic lateral sclerosis disease pathway; autophagy pathway; ASSOCIATED WITH coronary artery anomaly (inferred); coronary artery disease (inferred); Myocardial Ischemia (inferred); FOUND IN cytoplasm; cytoplasmic side of early endosome membrane; cytosol; INTERACTS WITH (+)-catechin; aflatoxin B1; all-trans-retinoic acid
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: OTTHUMP00000160334; OTTHUMP00000207855; RAB5; RAS-associated protein RAB5A; ras-related protein Rab-5A
Mus musculus (house mouse) : Rab5a (RAB5A, member RAS oncogene family)  MGI
Rattus norvegicus (Norway rat) : Rab5a (RAB5A, member RAS oncogene family)
Chinchilla lanigera (long-tailed chinchilla) : Rab5a (RAB5A, member RAS oncogene family)
Pan paniscus (bonobo/pygmy chimpanzee) : RAB5A (RAB5A, member RAS oncogene family)
Canis lupus familiaris (dog) : RAB5A (RAB5A, member RAS oncogene family)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rab5a (RAB5A, member RAS oncogene family)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38319,947,080 - 19,985,175 (+)NCBIGRCh38hg38GRCh38
GRCh37319,988,572 - 20,026,667 (+)NCBIGRCh37hg19GRCh37
Build 36319,963,760 - 20,001,647 (+)NCBINCBI36hg18NCBI36
Build 34319,963,762 - 20,001,647NCBI
Celera319,929,100 - 19,967,199 (+)NCBI
Cytogenetic Map3p24.3NCBImapview
HuRef319,928,511 - 19,966,511 (+)NCBI
CHM1_1319,940,747 - 19,978,758 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on RAB5A
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1342715
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2017-09-12
Status: ACTIVE