Gene: Msh6 (mutS homolog 6) Mus musculus
Symbol: Msh6
Name: mutS homolog 6
Description: ENCODES a protein that exhibits chromatin binding; damaged DNA binding; DNA binding; INVOLVED IN determination of adult lifespan; intrinsic apoptotic signaling pathway; intrinsic apoptotic signaling pathway in response to DNA damage; PARTICIPATES IN altered mismatch repair pathway; colorectal cancer pathway; endometrial cancer pathway; ASSOCIATED WITH abnormal mismatch repair; increased basal cell carcinoma incidence; increased gastrointestinal tumor incidence; ASSOCIATED WITH Adenocarcinoma of Lung (ortholog); Breast Neoplasms (ortholog); Breast-Ovarian Cancer, Familial, Susceptibility To, 1 (ortholog); FOUND IN intracellular; MutSalpha complex; nuclear chromatin; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU044881; AW550279; DNA mismatch repair protein Msh6; g/T mismatch-binding protein; GTBP; Gtmbp; mutS protein homolog 6; mutS-alpha 160 kDa subunit; p160
Homo sapiens : MSH6 (mutS homolog 6)  HGNC
Rattus norvegicus : Msh6 (mutS homolog 6)
more info ...
Related Pseudogenes: Gm11855  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381787,975,050 - 87,990,892 (+)NCBIGRCm38mm10GRCm38
MGSCv371788,374,390 - 88,390,232 (+)NCBIGRCm37mm9NCBIm37
MGSCv361787,883,410 - 87,899,389 (+)NCBImm8
Celera1792,385,348 - 92,401,193 (+)NCBI
Cytogenetic Map17 E4NCBImapview
cM Map1757.87NCBI

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Msh6
Entrez Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1321739
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2016-10-11
Status: ACTIVE