Gene: Msh6 (mutS homolog 6 (E. coli)) Mus musculus
Symbol: Msh6
Name: mutS homolog 6 (E. coli)
Description: ENCODES a protein that exhibits chromatin binding; damaged DNA binding; DNA binding; INVOLVED IN determination of adult lifespan; intrinsic apoptotic signaling pathway; intrinsic apoptotic signaling pathway in response to DNA damage; PARTICIPATES IN altered mismatch repair pathway; colorectal cancer pathway; endometrial cancer pathway; ASSOCIATED WITH abnormal mismatch repair; increased basal cell carcinoma incidence; increased gastrointestinal tumor incidence; ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); Colorectal Neoplasms, Hereditary Nonpolyposis (ortholog); FOUND IN intracellular; MutSalpha complex; nuclear chromatin; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU044881; AW550279; DNA mismatch repair protein Msh6; g/T mismatch-binding protein; GTBP; Gtmbp; mutS-alpha 160 kDa subunit; p160
Orthologs:
Homo sapiens : MSH6 (mutS homolog 6)  HGNC
Rattus norvegicus : Msh6 (mutS homolog 6)
more info ...
Related Pseudogenes: Gm11855  
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm381787,975,050 - 87,990,892+NCBI
Mouse cM Map1757.87 NCBI
Mouse Celera Assembly1792,385,348 - 92,401,193+NCBI
Mouse Genome Assembly Build 371788,374,390 - 88,390,232+NCBI
Mouse Genome Assembly Build 36.11788,374,424 - 88,390,403+NCBI
Mouse Cytogenetic Map17 E4 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Msh6
Entrez Gene
Ensembl Gene
Genome Browser
MGI Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1321739
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2014-06-10
Status: ACTIVE