Gene: Msh6 (mutS homolog 6 (E. coli)) Mus musculus
Symbol: Msh6
Name: mutS homolog 6 (E. coli)
Description: ENCODES a protein that exhibits chromatin binding; damaged DNA binding; DNA binding; INVOLVED IN determination of adult lifespan; intrinsic apoptotic signaling pathway; intrinsic apoptotic signaling pathway in response to DNA damage; PARTICIPATES IN altered mismatch repair pathway; colorectal cancer pathway; endometrial cancer pathway; ASSOCIATED WITH abnormal mismatch repair; increased basal cell carcinoma incidence; increased gastrointestinal tumor incidence; ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Cancer, Hereditary Nonpolyposis, Type 1 (ortholog); Colorectal Cancer, Hereditary Nonpolyposis, Type 5 (ortholog); FOUND IN intracellular; MutSalpha complex; nuclear chromatin; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU044881; AW550279; DNA mismatch repair protein Msh6; g/T mismatch-binding protein; GTBP; Gtmbp; mutS-alpha 160 kDa subunit; p160
Homo sapiens : MSH6 (mutS homolog 6)  HGNC
Rattus norvegicus : Msh6 (mutS homolog 6)
more info ...
Related Pseudogenes: Gm11855  
Latest Assembly: Mouse Genome Assembly Build 37
Mouse Genome Assembly GRCm381787,975,050 - 87,990,892+NCBI
Mouse cM Map1757.87 NCBI
Mouse Celera Assembly1792,385,348 - 92,401,193+NCBI
Mouse Genome Assembly Build 371788,374,390 - 88,390,232+NCBI
Mouse Genome Assembly Build 36.11787,883,410 - 87,899,389+NCBI
Mouse Cytogenetic Map17 E4 NCBI

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Disease Annotations
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Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

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RGD Object Information
RGD ID: 1321739
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2015-07-07
Status: ACTIVE