Gene: UPP1 (uridine phosphorylase 1) Homo sapiens
Symbol: UPP1
Name: uridine phosphorylase 1
Description: The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA (Watanabe and Uchida, 1995 [PubMed 7488099]).[supplied by OMIM, Aug 2009]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: OTTHUMP00000159566; OTTHUMP00000208692; UDRPASE; UP; UPASE; UPase 1; UPP; urdPase 1
Orthologs:
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38748,088,603 - 48,108,733 (+)NCBIGRCh38hg38GRCh38
GRCh37748,128,355 - 48,148,330 (+)NCBIGRCh37hg19GRCh37
Build 36748,094,880 - 48,114,855 (+)NCBINCBI36hg18NCBI36
Celera748,227,538 - 48,247,515 (+)NCBI
Cytogenetic Map7p12.3NCBImapview
HuRef748,013,793 - 48,033,924 (+)NCBI
CHM1_1748,131,900 - 48,152,030 (+)NCBI
CRA_TCAGchr7v2748,168,224 - 48,188,201 (+)NCBI
Model


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Genomics

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Sequence

Nucleotide Sequences
Protein Sequences
Promoters
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Additional Information

External Database Links
Nomenclature History
 
More on UPP1
Entrez Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
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RGD Object Information
RGD ID: 1313669
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2016-04-19
Status: ACTIVE