Gene: UPP1 (uridine phosphorylase 1)  Homo sapiens
Symbol: UPP1
Name: uridine phosphorylase 1
Description: The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA (Watanabe and Uchida, 1995 [PubMed 7488099]).[supplied by OMIM, Aug 2009]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: OTTHUMP00000159566; OTTHUMP00000208692; UDRPASE; UP; UPASE; UPase 1; UPP; urdPase 1; uridine phosphorylase 1
Orthologs: Mus musculus : Upp1 (uridine phosphorylase 1)  MGI
Rattus norvegicus : Upp1 (uridine phosphorylase 1)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1748,105,136 - 48,125,110+NCBI
Human Alternate Assembly CRA_TCAGchr7v2748,168,224 - 48,188,201+NCBI
Human Genome Assembly HuRef748,013,948 - 48,033,924+NCBI
Human Genome Assembly GRCh37748,128,355 - 48,148,330+NCBI
Human Genome Assembly Build 36748,094,880 - 48,114,855+NCBI
Human Cytogenetic Map7p12.3 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

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Sequence

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Nomenclature History
  
More on UPP1
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Ensembl Gene
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Vista + UCSC

RGD Object Information
RGD ID: 1313669
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2013-03-05
Status: ACTIVE



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