Gene: Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1) Mus musculus
Symbol: Hsd11b1
Name: hydroxysteroid 11-beta dehydrogenase 1
Description: ENCODES a protein that exhibits 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity; NADP binding (ortholog); oxidoreductase activity (ortholog); INVOLVED IN lung development; oxidation-reduction process; glucocorticoid biosynthetic process (ortholog); PARTICIPATES IN aldosterone signaling pathway; steroid hormone biosynthetic pathway; ASSOCIATED WITH abnormal abdominal fat pad morphology; abnormal amniotic fluid composition; abnormal bone marrow cell physiology; ASSOCIATED WITH Obesity; CORTISONE REDUCTASE DEFICIENCY 2 (ortholog); Diabetes Mellitus, Type 2 (ortholog); FOUND IN apical part of cell (ortholog); cytoplasm (ortholog); intracellular membrane-bounded organelle (ortholog); INTERACTS WITH (S)-nicotine; 11-dehydrocorticosterone; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 11-beta-HSD1; 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11beta-HSD-1; 11beta-HSD1A; 11beta-hydroxysteroid dehydrogenase type 1; corticosteroid 11-beta-dehydrogenase isozyme 1; Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A); OTTMUSP00000039927; OTTMUSP00000039928; OTTMUSP00000039929; OTTMUSP00000039930
Latest Assembly: Mouse Genome Assembly Build 37
Mouse Genome Assembly GRCm381193,221,640 - 193,264,049-NCBI
Mouse cM Map1 -NCBI
Mouse Celera Assembly1200,096,784 - 200,141,189-NCBI
Mouse Genome Assembly Build 371195,047,834 - 195,090,239-NCBI
Mouse Genome Assembly Build 36.11194,922,413 - 194,964,769-NCBI
Mouse Cytogenetic Map1 H6 NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hsd11b1
Entrez Gene
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RGD Object Information
RGD ID: 10734
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2015-03-19
Status: ACTIVE