Gene: Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1) Mus musculus
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Symbol: Hsd11b1
Name: hydroxysteroid 11-beta dehydrogenase 1
Description: ENCODES a protein that exhibits 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity; NADP binding (ortholog); steroid binding (ortholog); INVOLVED IN lung development; glucocorticoid biosynthetic process (ortholog); glucocorticoid catabolic process (ortholog); PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH abnormal abdominal fat pad morphology; abnormal amniotic fluid composition; abnormal bone marrow cell physiology; ASSOCIATED WITH Obesity; Arthritis, Rheumatoid (ortholog); Cortisone Reductase Deficiency (ortholog); FOUND IN apical part of cell (ortholog); cytoplasm (ortholog); intracellular membrane-bounded organelle (ortholog); INTERACTS WITH 11-dehydrocorticosterone; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 11-beta-HSD1; 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11beta-HSD-1; 11beta-HSD1A; 11beta-hydroxysteroid dehydrogenase type 1; corticosteroid 11-beta-dehydrogenase isozyme 1; Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A); OTTMUSP00000039927; OTTMUSP00000039928; OTTMUSP00000039929; OTTMUSP00000039930
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381193,221,640 - 193,264,049 (-)NCBIGRCm38mm10GRCm38
MGSCv371195,047,834 - 195,090,239 (-)NCBIGRCm37mm9NCBIm37
MGSCv361194,922,413 - 194,964,769 (-)NCBImm8
Celera1200,096,784 - 200,141,189 (-)NCBI
Cytogenetic Map1 H6NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hsd11b1
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
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RGD Object Information
RGD ID: 10734
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2016-11-22
Status: ACTIVE