Gene: Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1) Mus musculus
Symbol: Hsd11b1
Name: hydroxysteroid 11-beta dehydrogenase 1
Description: ENCODES a protein that exhibits 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity; NADP binding (ortholog); steroid binding (ortholog); INVOLVED IN lung development; glucocorticoid biosynthetic process (ortholog); glucocorticoid catabolic process (ortholog); PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH abnormal abdominal fat pad morphology; abnormal amniotic fluid composition; abnormal bone marrow cell physiology; ASSOCIATED WITH Obesity; Cortisone Reductase Deficiency 2 (ortholog); Diabetes Mellitus, Type 2 (ortholog); FOUND IN apical part of cell (ortholog); cytoplasm (ortholog); intracellular membrane-bounded organelle (ortholog); INTERACTS WITH 11-dehydrocorticosterone; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 11-beta-HSD1; 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11beta-HSD-1; 11beta-HSD1A; 11beta-hydroxysteroid dehydrogenase type 1; corticosteroid 11-beta-dehydrogenase isozyme 1; Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A); OTTMUSP00000039927; OTTMUSP00000039928; OTTMUSP00000039929; OTTMUSP00000039930
Latest Assembly: Mouse Genome Assembly Build 37
Mouse Genome Assembly GRCm381193,221,640 - 193,264,049-NCBI
Mouse Celera Assembly1200,096,784 - 200,141,189-NCBI
Mouse Genome Assembly Build 371195,047,834 - 195,090,239-NCBI
Mouse Genome Assembly Build 36.11194,922,413 - 194,964,769-NCBI
Mouse Cytogenetic Map1 H6 NCBI

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Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

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RGD Object Information
RGD ID: 10734
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2015-12-29
Status: ACTIVE