Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1)

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Keyword

Gene: Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1) Mus musculus

Symbol:

Hsd11b1

Name:

hydroxysteroid 11-beta dehydrogenase 1

Description:

ENCODES a protein that exhibits 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity; NADP binding (ortholog); oxidoreductase activity (ortholog); INVOLVED IN lung development; oxidation-reduction process; glucocorticoid biosynthetic process (ortholog); PARTICIPATES IN aldosterone signaling pathway; steroid hormone biosynthetic pathway; ASSOCIATED WITH abnormal abdominal fat pad morphology; abnormal brainstem morphology; abnormal circulating cholesterol level; ASSOCIATED WITH Obesity; Diabetes Mellitus, Type 2 (ortholog); Hyperlipidemias (ortholog); FOUND IN apical part of cell (ortholog); cytoplasm (ortholog); intracellular membrane-bounded organelle (ortholog); INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

11-beta-HSD1; 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11beta-HSD-1; 11beta-HSD1A; 11beta-hydroxysteroid dehydrogenase type 1; corticosteroid 11-beta-dehydrogenase isozyme 1; Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A); OTTMUSP00000039927; OTTMUSP00000039928; OTTMUSP00000039929; OTTMUSP00000039930

Orthologs:

Homo sapiens : HSD11B1 (hydroxysteroid (11-beta) dehydrogenase 1) HGNC
Rattus norvegicus : Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1)

Latest Assembly:

Mouse Genome Assembly Build 37

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	1	193,221,640 - 193,264,045	-	NCBI
Mouse cM Map	1		-	NCBI
Mouse Celera Assembly	1	200,096,784 - 200,141,189	-	NCBI
Mouse Genome Assembly Build 37	1	195,047,834 - 195,090,239	-	NCBI
Mouse Genome Assembly Build 36.1	1	195,047,834 - 195,090,239	-	NCBI
Mouse Cytogenetic Map	1	H6		NCBI