GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3963
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vldlr
Name: very low density lipoprotein receptor
Acc ID: CHEBI:5292
Term: geldanamycin
Definition: A 19-membered macrocyle incorporating a benzoquinone ring and a lactam functionality. it is an ansamycin antibiotic and thus shows antimicrobial activity against many gram-positive and some gram-negative bacteria.
CasRN: 30562-34-6
Chemical ID: MESH:C001277
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDgeldanamycin inhibits the reaction [IL1B protein results in decreased expression of VLDLR protein]

PMID:15808840
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