RGD ID: 3963
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vldlr
Name: very low density lipoprotein receptor
Acc ID: CHEBI:5292
Term: geldanamycin
Definition: An ansamycin consisting of a 19-membered macrocyle incorporating a benzoquinone ring and a lactam functionality. It shows antimicrobial activity against many Gram-positive and some Gram-negative bacteria.
Definition Source(s): CAS:30562-34-6, KEGG:C11222, KNApSAcK:C00018795, PDBeChem:GDM, PMID:21983172, PMID:21985437, PMID:22050565, PMID:22136518, PMID:22138446, PMID:22215907, PMID:22277058, PMID:22361388, Reaxys:14205884, Wikipedia:Geldanamycin
Chemical ID: MESH:C001277
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDgeldanamycin inhibits the reaction [IL1B protein results in decreased expression of VLDLR protein]

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