RGD ID: 2184
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Avp
Name: arginine vasopressin
Acc ID: CHEBI:49662
Term: indometacin
Definition: A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Definition Source(s): Beilstein:497341, ChemIDplus:53-86-1, CiteXplore:22931205, CiteXplore:23992308, CiteXplore:5952296, CiteXplore:6039425, DrugBank:DB00328, Gmelin:1446006, HMDB:HMDB14473, KEGG COMPOUND:53-86-1, KEGG COMPOUND:C01926, KEGG DRUG:D00141, KNApSAcK:C00030512, MetaCyc:CPD-10545, NIST Chemistry WebBook:53-86-1, Patent:BE379378, Patent:US3161654, PDBeChem:IMN, Reaxys:497341, Wikipedia:Indometacin
Chemical ID: MESH:D007213
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases secretionISORGD:689686480464CTDIndomethacin results in decreased secretion of AVP protein

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