GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62043
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Xdh
Name: xanthine dehydrogenase
Acc ID: CHEBI:34648
Term: clofibric acid
Definition: A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.
Definition Source(s): Beilstein:1874067, CAS:882-09-7, CAS:882-09-7, CAS:882-09-7, KEGG:C13700, KEGG:D07723, LINCS:LSM-2427, Pesticides:clofibric%20acid, PMID:16442995, PMID:17431116, PMID:23062606, PMID:23135717, PMID:23352585, PMID:7320112, PMID:8944746, Reaxys:1874067, Wikipedia:Clofibric_acid
Chemical ID: MESH:D002995
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of XDH mRNA

PMID:17602206
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