RGD ID: 2866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifng
Name: interferon gamma
Acc ID: CHEBI:27974
Term: estriol
Definition: A 3-hydroxy steroid that is estra-1,3,5(10)-trien-3-ol substituted by additional hydroxy groups at positions 16 and 17 (16alpha,17beta-stereoisomer).
Definition Source(s): Beilstein:2508172, ChemIDplus:50-27-1, CiteXplore:10083784, CiteXplore:11133265, CiteXplore:1171044, CiteXplore:12424769, CiteXplore:14634144, CiteXplore:16009196, CiteXplore:16097001, CiteXplore:16112271, CiteXplore:16202579, CiteXplore:1718632, CiteXplore:23777262, CiteXplore:2621854, CiteXplore:2994907, CiteXplore:3583036, CiteXplore:3629582, CiteXplore:6374294, CiteXplore:6640903, CiteXplore:6690116, CiteXplore:7139918, CiteXplore:752645, CiteXplore:8469492, CiteXplore:8478958, CiteXplore:9373313, DrugBank:DB04573, HMDB:HMDB00153, KEGG COMPOUND:50-27-1, KEGG COMPOUND:C05141, KEGG DRUG:D00185, LIPID MAPS:LMST02010003, MetaCyc:ESTRIOL, NIST Chemistry WebBook:50-27-1, PDBeChem:ESL, Reaxys:2508172, Wikipedia:Estriol
Chemical ID: MESH:D004964
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7374886480464CTDEstriol results in decreased expression of IFNG protein

multiple interactionsISORGD:7374886480464CTDEstriol inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased abundance of Nitric Oxide]

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