GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62076
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptges
Name: prostaglandin E synthase
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that has formula C14H12O3.
CasRN: 501-36-0
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [Dextran Sulfate results in increased expression of PTGES protein]

PMID:19228061
multiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGES protein]

resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGES mRNA]

PMID:17927823
multiple interactionsISORGD:623686480464CTDresveratrol inhibits the reaction [Dextran Sulfate results in increased expression of PTGES protein]

PMID:20132809
multiple interactionsISORGD:690326480464CTD[Coumestrol co-treated with resveratrol] results in increased expression of PTGES mRNA

PMID:19167446
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