GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3859
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Thrsp
Name: thyroid hormone responsive
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
CasRN: 50892-23-4
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDpirinixic acid results in decreased expression of THRSP mRNA

PMID:19162173
decreases expressionISORGD:114176480464CTDpirinixic acid results in decreased expression of THRSP mRNA

PMID:16221962, PMID:20059764, PMID:20813756, PMID:23811191
increases expressionISORGD:114176480464CTDpirinixic acid results in increased expression of THRSP mRNA

PMID:18445702
multiple interactionsISORGD:114176480464CTD[pirinixic acid co-treated with PPARA] results in decreased expression of THRSP mRNA

PMID:20813756
multiple interactionsISORGD:114176480464CTDPPARA protein promotes the reaction [pirinixic acid results in decreased expression of THRSP mRNA]

PMID:20059764
Go Back to source page   Continue to Ontology report