ONTOLOGY REPORT - ANNOTATIONS


Term:G protein mediated signaling pathway via Galphaq family
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Accession:PW:0000229 term browser browse the term
Definition:Based on sequence similarity, the Galpha genes have been grouped into four classes. Exchange of GDP to GTP promoted through binding to receptors dissociates the heterotrimeric Galpha/beta/gamma complex. GTP-bound Galpha can then interact with downstream effectors. Lipid modification of Galpha regulates membrane localization and interactions with specific effectors.


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G protein mediated signaling pathway via Galphaq family term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adra1a adrenoceptor alpha 1A GBrowse link 15 48,197,628 48,297,316 RGD:1559318
G Adra1b adrenoceptor alpha 1B GBrowse link 10 29,233,972 29,291,344 RGD:1559318
G Adra1d adrenoceptor alpha 1D GBrowse link 3 130,621,199 130,637,207 RGD:1559318
G Agtr1a angiotensin II receptor, type 1a GBrowse link 17 37,217,810 37,270,540 RGD:70819
RGD:629553
G Agtr1b angiotensin II receptor, type 1b GBrowse link 2 124,879,262 124,954,378 RGD:629553
G Avpr1a arginine vasopressin receptor 1A GBrowse link 7 67,528,358 67,532,282 RGD:1579891
G Avpr1b arginine vasopressin receptor 1B GBrowse link 13 53,443,235 53,453,450 RGD:1579891
RGD:2312649
G Bdkrb1 bradykinin receptor B1 GBrowse link 6 138,631,450 138,633,866 RGD:7401223
G Bdkrb2 bradykinin receptor B2 GBrowse link 6 138,615,812 138,622,272 RGD:7401223
G Casr calcium-sensing receptor GBrowse link 11 70,278,784 70,352,137 RGD:7207059
RGD:7207227
G Chrm1 cholinergic receptor, muscarinic 1 GBrowse link 1 231,806,335 231,822,359 RGD:8549585
G Chrm3 cholinergic receptor, muscarinic 3 GBrowse link 17 65,753,665 66,217,211 RGD:8549585
G Chrm5 cholinergic receptor, muscarinic 5 GBrowse link 3 110,560,292 110,632,938 RGD:8549585
G Ghsr growth hormone secretagogue receptor GBrowse link 2 132,784,207 132,789,319 RGD:1642818
G Gna11 guanine nucleotide binding protein, alpha 11 GBrowse link 7 11,200,712 11,214,475 RGD:1579891
RGD:5131495
RGD:8549590
G Gna14 guanine nucleotide binding protein, alpha 14 GBrowse link 1 242,484,562 242,665,783 RGD:5131495
RGD:8549590
G Gna15 guanine nucleotide binding protein, alpha 15 GBrowse link 7 11,221,467 11,242,341 RGD:728647
RGD:5131495
G Gnaq guanine nucleotide binding protein (G protein), q polypeptide GBrowse link 1 240,497,178 240,736,860 RGD:1579891
RGD:1642020
RGD:5131495
RGD:8549590
G Hcrtr1 hypocretin (orexin) receptor 1 GBrowse link 5 152,064,507 152,073,882 RGD:1642020
G Hcrtr2 hypocretin (orexin) receptor 2 GBrowse link 8 82,883,206 82,998,507 RGD:1642020
G Lpar1 lysophosphatidic acid receptor 1 GBrowse link 5 79,707,131 79,825,313 RGD:1626471
G Lpar3 lysophosphatidic acid receptor 3 GBrowse link 2 270,610,856 270,679,592 RGD:1626471
G Oxtr oxytocin receptor GBrowse link 4 207,701,360 207,717,840 RGD:1579891
RGD:2304227
G Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link 3 134,211,557 134,908,321 RGD:5131495
G Plcb2 phospholipase C, beta 2 GBrowse link 3 117,038,677 117,058,132 RGD:5131495
G Plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) GBrowse link 1 229,198,739 229,215,831 RGD:5131495
G Plcb4 phospholipase C, beta 4 GBrowse link 3 135,089,551 135,459,248 RGD:5131495
G Pth1r parathyroid hormone 1 receptor GBrowse link 8 118,325,190 118,353,210 RGD:7207455
RGD:7207465
RGD:7207470
G Rgs2 regulator of G-protein signaling 2 GBrowse link 13 65,831,386 65,833,989 RGD:5133418
RGD:7207227
G Rgs4 regulator of G-protein signaling 4 GBrowse link 13 92,682,956 92,689,247 RGD:7207227
G Rgs5 regulator of G-protein signaling 5 GBrowse link 13 92,595,346 92,631,357 RGD:7207228

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  pathway 51689
    signaling pathway 21699
      G protein mediated signaling pathway 484
        heterotrimeric G protein mediated signaling pathway 310
          G protein mediated signaling pathway via Galphaq family 127
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