ONTOLOGY REPORT - ANNOTATIONS


Term:G protein mediated signaling pathway via Galphaq family
go back to main search page
Accession:PW:0000229 term browser browse the term
Definition:Based on sequence similarity, the Galpha genes have been grouped into four classes. Exchange of GDP to GTP promoted through binding to receptors dissociates the heterotrimeric Galpha/beta/gamma complex. GTP-bound Galpha can then interact with downstream effectors. Lipid modification of Galpha regulates membrane localization and interactions with specific effectors.


  • Rat
  • Mouse
  • Human
  • All
  • show annotations for term's descendants
  •     Sort by:
  • view all columns
G protein mediated signaling pathway via Galphaq family term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adra1a adrenoceptor alpha 1A GBrowse link 15 46,173,429 46,263,198 RGD:1559318
G Adra1b adrenoceptor alpha 1B GBrowse link 10 28,889,092 28,946,889 RGD:1559318
G Adra1d adrenoceptor alpha 1D GBrowse link 3 119,279,974 119,295,985 RGD:1559318
G Agtr1a angiotensin II receptor, type 1a GBrowse link 17 40,629,318 40,684,982 RGD:70819
RGD:629553
G Agtr1b angiotensin II receptor, type 1b GBrowse link 2 105,503,269 105,602,591 RGD:629553
G Avpr1a arginine vasopressin receptor 1A GBrowse link 7 62,225,537 62,229,461 RGD:1579891
G Avpr1b arginine vasopressin receptor 1B GBrowse link 13 44,537,103 44,547,318 RGD:1579891
RGD:2312649
G Bdkrb1 bradykinin receptor B1 GBrowse link 6 129,760,129 129,762,545 RGD:7401223
G Bdkrb2 bradykinin receptor B2 GBrowse link 6 129,744,781 129,748,851 RGD:7401223
G Casr calcium-sensing receptor GBrowse link 11 66,084,169 66,153,292 RGD:7207059
RGD:7207227
G Chrm1 cholinergic receptor, muscarinic 1 GBrowse link 1 211,351,738 211,353,120 RGD:8549585
G Chrm3 cholinergic receptor, muscarinic 3 GBrowse link 17 71,214,906 71,218,463 RGD:8549585
G Chrm5 cholinergic receptor, muscarinic 5 GBrowse link 3 98,326,809 98,378,531 RGD:8549585
G Ghsr growth hormone secretagogue receptor GBrowse link 2 113,269,623 113,272,999 RGD:1642818
G Gna11 guanine nucleotide binding protein, alpha 11 GBrowse link 7 9,636,748 9,662,492 RGD:1579891
RGD:5131495
RGD:8549590
G Gna14 guanine nucleotide binding protein, alpha 14 GBrowse link 1 219,906,120 219,983,252 RGD:5131495
RGD:8549590
G Gna15 guanine nucleotide binding protein, alpha 15 GBrowse link 7 9,669,956 9,689,442 RGD:728647
RGD:5131495
G Gnaq guanine nucleotide binding protein (G protein), q polypeptide GBrowse link 1 219,520,998 219,764,401 RGD:1579891
RGD:1642020
RGD:5131495
RGD:8549590
G Hcrtr1 hypocretin (orexin) receptor 1 GBrowse link 5 149,160,739 149,170,736 RGD:1642020
G Hcrtr2 hypocretin (orexin) receptor 2 GBrowse link 8 81,068,303 81,196,608 RGD:1642020
G Lpar1 lysophosphatidic acid receptor 1 GBrowse link 5 76,449,470 76,571,458 RGD:1626471
G Lpar3 lysophosphatidic acid receptor 3 GBrowse link 2 244,431,789 244,510,815 RGD:1626471
G Oxtr oxytocin receptor GBrowse link 4 148,314,089 148,326,797 RGD:1579891
RGD:2304227
G Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link 3 122,797,718 123,523,675 RGD:5131495
G Plcb2 phospholipase C, beta 2 GBrowse link 3 105,203,524 105,223,342 RGD:5131495
G Plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) GBrowse link 1 209,628,425 209,643,694 RGD:5131495
G Plcb4 phospholipase C, beta 4 GBrowse link 3 123,706,313 124,077,381 RGD:5131495
G Pth1r parathyroid hormone 1 receptor GBrowse link 8 115,099,763 115,119,362 RGD:7207455
RGD:7207465
RGD:7207470
G Rgs2 regulator of G-protein signaling 2 GBrowse link 13 57,891,849 57,894,452 RGD:5133418
RGD:7207227
G Rgs4 regulator of G-protein signaling 4 GBrowse link 13 85,533,882 85,540,173 RGD:7207227
G Rgs5 regulator of G-protein signaling 5 GBrowse link 13 85,445,325 85,482,294 RGD:7207228

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 17687
    signaling pathway 7744
      G protein mediated signaling pathway 178
        heterotrimeric G protein mediated signaling pathway 111
          G protein mediated signaling pathway via Galphaq family 45
paths to the root