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Term:G protein mediated signaling pathway via Galphaq family
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Accession:PW:0000229 term browser browse the term
Definition:Based on sequence similarity, the Galpha genes have been grouped into four classes. Exchange of GDP to GTP promoted through binding to receptors dissociates the heterotrimeric Galpha/beta/gamma complex. GTP-bound Galpha can then interact with downstream effectors. Lipid modification of Galpha regulates membrane localization and interactions with specific effectors.


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G protein mediated signaling pathway via Galphaq family term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:1559318
G Adra1b adrenoceptor alpha 1B JBrowse link 10 29,392,762 29,450,644 RGD:1559318
G Adra1d adrenoceptor alpha 1D JBrowse link 3 124,129,558 124,145,566 RGD:1559318
G Agtr1a angiotensin II receptor, type 1a JBrowse link 17 35,907,102 35,958,136 RGD:70819
RGD:629553
G Agtr1b angiotensin II receptor, type 1b JBrowse link 2 105,149,020 105,224,335 RGD:629553
G Avpr1a arginine vasopressin receptor 1A JBrowse link 7 67,341,366 67,345,290 RGD:1579891
G Avpr1b arginine vasopressin receptor 1B JBrowse link 13 48,367,307 48,378,831 RGD:1579891
RGD:2312649
G Bdkrb1 bradykinin receptor B1 JBrowse link 6 129,437,423 129,441,553 RGD:7401223
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:7401223
G Casr calcium-sensing receptor JBrowse link 11 67,188,204 67,262,261 RGD:7207059
RGD:7207227
G Chrm1 cholinergic receptor, muscarinic 1 JBrowse link 1 224,869,087 224,885,101 RGD:8549585
G Chrm3 cholinergic receptor, muscarinic 3 JBrowse link 17 63,990,599 64,463,222 RGD:8549585
G Chrm5 cholinergic receptor, muscarinic 5 JBrowse link 3 103,966,451 104,018,815 RGD:8549585
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:11041142
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:11041142
G Drd5 dopamine receptor D5 JBrowse link 14 77,220,579 77,222,006 RGD:11041142
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:1642818
G Gna11 guanine nucleotide binding protein, alpha 11 JBrowse link 7 11,033,400 11,047,284 RGD:1579891
RGD:5131495
RGD:8549590
G Gna14 G protein subunit alpha 14 JBrowse link 1 235,165,775 235,347,986 RGD:5131495
RGD:8549590
G Gna15 guanine nucleotide binding protein, alpha 15 JBrowse link 7 11,054,249 11,075,152 RGD:728647
RGD:5131495
G Gnaq G protein subunit alpha q JBrowse link 1 233,382,778 233,622,584 RGD:1579891
RGD:1642020
RGD:5131495
RGD:8549590
G Hcrtr1 hypocretin receptor 1 JBrowse link 5 148,346,029 148,355,404 RGD:1642020
G Hcrtr2 hypocretin receptor 2 JBrowse link 8 83,307,684 83,421,612 RGD:1642020
G Lpar1 lysophosphatidic acid receptor 1 JBrowse link 5 75,557,038 75,678,067 RGD:1626471
G Lpar3 lysophosphatidic acid receptor 3 JBrowse link 2 252,090,634 252,159,221 RGD:1626471
G Oxtr oxytocin receptor JBrowse link 4 144,399,326 144,417,598 RGD:1579891
RGD:2304227
G Plcb1 phospholipase C beta 1 JBrowse link 3 127,721,244 128,419,565 RGD:5131495
G Plcb2 phospholipase C, beta 2 JBrowse link 3 110,497,760 110,517,563 RGD:5131495
G Plcb3 phospholipase C beta 3 JBrowse link 1 222,207,887 222,224,993 RGD:5131495
G Plcb4 phospholipase C, beta 4 JBrowse link 3 128,601,163 128,971,720 RGD:5131495
G Pth1r parathyroid hormone 1 receptor JBrowse link 8 118,984,531 119,012,803 RGD:7207455
RGD:7207465
RGD:7207470
G Rgs2 regulator of G-protein signaling 2 JBrowse link 13 60,846,458 60,849,061 RGD:5133418
RGD:7207227
G Rgs4 regulator of G-protein signaling 4 JBrowse link 13 88,054,817 88,061,108 RGD:7207227
G Rgs5 regulator of G-protein signaling 5 JBrowse link 13 87,966,820 88,002,831 RGD:7207228

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  pathway 89237
    signaling pathway 22870
      G protein mediated signaling pathway 652
        heterotrimeric G protein mediated signaling pathway 379
          G protein mediated signaling pathway via Galphaq family 136
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