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Term:regulation of insulin receptor signaling pathway
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Accession:GO:0046626 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of insulin receptor signaling.
Synonyms:exact_synonym: regulation of insulin receptor signalling pathway


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regulation of insulin receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Baiap2l1 BAI1-associated protein 2-like 1 JBrowse link 12 12,226,967 12,321,172 RGD:1600115
G Ccnd3 cyclin D3 JBrowse link 9 15,404,816 15,410,905 RGD:1624291
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:1624291
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 JBrowse link 13 48,679,726 48,709,663 RGD:1624291
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 71,540,870 71,585,906 RGD:1600115
RGD:1624291
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:1624291
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1625241
G Rbm4 RNA binding motif protein 4 JBrowse link 1 220,038,403 220,049,756 RGD:1624291
G Sesn3 sestrin 3 JBrowse link 8 12,823,060 12,878,749 RGD:1624291
G Sik2 salt-inducible kinase 2 JBrowse link 8 55,309,005 55,408,608 RGD:1624291
G Tsc2 tuberous sclerosis 2 JBrowse link 10 13,962,006 13,996,684 RGD:1624291
G Vwa2 von Willebrand factor A domain containing 2 JBrowse link 1 277,689,478 277,730,407 RGD:1600115
RGD:1624291
negative regulation of insulin receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahsg alpha-2-HS-glycoprotein JBrowse link 11 81,711,269 81,717,594 RGD:632173
G Ankrd26 ankyrin repeat domain 26 JBrowse link 4 150,548,656 150,616,928 RGD:1624291
G Cish cytokine inducible SH2-containing protein JBrowse link 8 116,054,547 116,059,494 RGD:1600115
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 1 21,748,201 21,813,205 RGD:1600115
RGD:1624291
G Gpr21 G protein-coupled receptor 21 JBrowse link 3 21,764,377 21,767,300 RGD:1600115
RGD:1624291
G Grb10 growth factor receptor bound protein 10 JBrowse link 14 92,021,851 92,122,249 RGD:1600115
RGD:1624291
G Grb14 growth factor receptor bound protein 14 JBrowse link 3 50,937,403 51,054,447 RGD:61620
RGD:2307023
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 1 82,097,244 82,108,238 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Inpp5f inositol polyphosphate-5-phosphatase F JBrowse link 1 200,037,749 200,116,524 RGD:11059577
G Inpp5k inositol polyphosphate-5-phosphatase K JBrowse link 10 63,775,639 63,796,879 RGD:1600115
RGD:1624291
G Inppl1 inositol polyphosphate phosphatase-like 1 JBrowse link 1 166,898,177 166,912,524 RGD:2312443
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:8554248
G Kank1 KN motif and ankyrin repeat domains 1 JBrowse link 1 243,201,073 243,398,531 RGD:1600115
RGD:1624291
G Lmbrd1 LMBR1 domain containing 1 JBrowse link 9 30,939,555 31,038,381 RGD:1600115
RGD:1624291
G Mstn myostatin JBrowse link 9 53,310,977 53,315,804 RGD:1600115
RGD:1624291
G Ncoa5 nuclear receptor coactivator 5 JBrowse link 3 161,465,733 161,498,951 RGD:1600115
RGD:1624291
G Nucb2 nucleobindin 2 JBrowse link 1 185,106,773 185,143,278 RGD:9831186
G Pid1 phosphotyrosine interaction domain containing 1 JBrowse link 9 91,667,748 91,683,468 RGD:1600115
RGD:1624291
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:1624291
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:8553365
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1600115
RGD:1624291
G Prkcq protein kinase C, theta JBrowse link 17 70,971,915 71,105,286 RGD:1600115
RGD:1624291
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:1600115
RGD:1624291
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1600115
RGD:1624291
G Ptpre protein tyrosine phosphatase, receptor type, E JBrowse link 1 207,820,719 207,987,123 RGD:1624291
RGD:8553759
G Ptprf protein tyrosine phosphatase, receptor type, F JBrowse link 5 137,036,936 137,112,930 RGD:1642757
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:2298860
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:1624291
RGD:8554230
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:1600115
RGD:1624291
G Socs2 suppressor of cytokine signaling 2 JBrowse link 7 36,495,496 36,500,878 RGD:1600115
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:1600115
RGD:1624291
G Trim72 tripartite motif containing 72 JBrowse link 1 199,450,042 199,457,902 RGD:1600115
RGD:1624291
G Tsc1 tuberous sclerosis 1 JBrowse link 3 7,219,955 7,269,063 RGD:1600115
G Tsc2 tuberous sclerosis 2 JBrowse link 10 13,962,006 13,996,684 RGD:1600115
G Tsc2_v1 tuberous sclerosis 2, variant 1 RGD:1600115
G Tsc2_v2 tuberous sclerosis 2, variant 2 RGD:1600115
G Ybx1 Y box binding protein 1 JBrowse link 5 138,319,754 138,336,721 RGD:727501
positive regulation of insulin receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipor1 adiponectin receptor 1 JBrowse link 13 51,240,470 51,260,233 RGD:2317907
G Fam132a family with sequence similarity 132, member A JBrowse link 5 173,390,901 173,395,276 RGD:1600115
RGD:1624291
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:1600115
RGD:1624291
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:1624291
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:8553881
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:5128575
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1624291
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 JBrowse link 13 48,679,726 48,709,663 RGD:1600115
RGD:1624291
G Osbpl8 oxysterol binding protein-like 8 JBrowse link 7 53,878,906 54,030,110 RGD:1600115
RGD:1624291
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:8553908
G Serpina12 serpin family A member 12 JBrowse link 6 127,696,501 127,711,238 RGD:1600115
RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1600115
RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1581139

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 501354
    signaling 61394
      regulation of signaling 23118
        regulation of signal transduction 19651
          regulation of insulin receptor signaling pathway 216
            negative regulation of insulin receptor signaling pathway + 139
            positive regulation of insulin receptor signaling pathway + 46
            regulation of insulin receptor signaling pathway involved in determination of adult lifespan + 0
Path 2
Term Annotations click to browse term
  biological_process 501354
    response to stimulus 118946
      response to chemical 39320
        response to organic substance 24075
          response to organonitrogen compound 4655
            response to peptide 2077
              response to peptide hormone 1904
                response to insulin 1209
                  cellular response to insulin stimulus 958
                    insulin receptor signaling pathway 502
                      regulation of insulin receptor signaling pathway 216
                        negative regulation of insulin receptor signaling pathway + 139
                        positive regulation of insulin receptor signaling pathway + 46
                        regulation of insulin receptor signaling pathway involved in determination of adult lifespan + 0
paths to the root