ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of insulin receptor signaling pathway
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Accession:GO:0046626 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of insulin receptor signaling.
Synonyms:exact_synonym: regulation of insulin receptor signalling pathway


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regulation of insulin receptor signaling pathway term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase GBrowse link X 72,390,218 72,435,241 RGD:1600115
RGD:1624291
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 GBrowse link 3 170,816,897 170,866,071 RGD:1625241
G Rbm4 RNA binding motif protein 4 GBrowse link 1 226,903,520 226,913,901 RGD:1624291
G Sik2 salt-inducible kinase 2 RGD:1624291
G Tsc2 tuberous sclerosis 2 GBrowse link 10 13,778,990 13,813,725 RGD:1624291
G Vwa2 von Willebrand factor A domain containing 2 GBrowse link 1 285,069,617 285,110,373 RGD:1600115
RGD:1624291
negative regulation of insulin receptor signaling pathway term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ahsg alpha-2-HS-glycoprotein GBrowse link 11 84,799,840 84,805,423 RGD:632173
G Ankrd26 ankyrin repeat domain 26 GBrowse link 4 216,472,517 216,540,754 RGD:1600115
RGD:1624291
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 GBrowse link 1 23,228,262 23,292,896 RGD:1600115
RGD:1624291
G Gpr21 G protein-coupled receptor 21 GBrowse link 3 27,001,363 27,006,936 RGD:1600115
RGD:1624291
G Grb10 growth factor receptor bound protein 10 GBrowse link 14 91,818,383 91,914,937 RGD:1600115
RGD:1624291
G Grb14 growth factor receptor bound protein 14 GBrowse link 3
3
57,679,758
57,578,226
57,695,025
57,619,404
RGD:61620
RGD:2307023
G Gsk3a glycogen synthase kinase 3 alpha GBrowse link 1 83,365,717 83,374,707 RGD:1624291
G Il1b interleukin 1 beta GBrowse link 3 128,133,929 128,140,354 RGD:1600115
RGD:1624291
G Inpp5k inositol polyphosphate-5-phosphatase K GBrowse link 10 64,209,340 64,228,728 RGD:1600115
RGD:1624291
G Inppl1 inositol polyphosphate phosphatase-like 1 GBrowse link 1 173,087,891 173,102,238 RGD:2312443
G Irs1 insulin receptor substrate 1 GBrowse link 9 87,782,499 87,835,248 RGD:8554248
G Kank1 KN motif and ankyrin repeat domains 1 GBrowse link 1 250,464,788 250,659,569 RGD:1600115
RGD:1624291
G Lmbrd1 LMBR1 domain containing 1 GBrowse link 9 29,762,573 29,854,653 RGD:1600115
RGD:1624291
G Mir143 microRNA 143 GBrowse link 18 56,200,186 56,200,290 RGD:1624291
G Ncoa5 nuclear receptor coactivator 5 GBrowse link 3 167,650,206 167,683,424 RGD:1624291
G Pid1 phosphotyrosine interaction domain containing 1 GBrowse link 9 91,403,609 91,419,329 RGD:1600115
RGD:1624291
G Prkca protein kinase C, alpha GBrowse link 10 95,919,013 96,311,328 RGD:1600115
RGD:1624291
G Prkcb protein kinase C, beta GBrowse link 1 199,295,067 199,639,140 RGD:8553365
G Prkcd protein kinase C, delta GBrowse link 16 6,588,990 6,608,725 RGD:1600115
RGD:1624291
G Prkcq protein kinase C, theta GBrowse link 17 72,669,688 72,800,895 RGD:1600115
RGD:1624291
G Prkcz protein kinase C, zeta GBrowse link 5 176,116,787 176,228,206 RGD:1600115
RGD:1624291
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 GBrowse link 18 62,600,260 62,671,979 RGD:1600115
RGD:1624291
G Ptpre protein tyrosine phosphatase, receptor type, E GBrowse link 1 214,818,446 214,920,034 RGD:1624291
RGD:8553759
G Ptprf protein tyrosine phosphatase, receptor type, F GBrowse link 5 140,825,315 140,901,672 RGD:1642757
G Rela v-rel avian reticuloendotheliosis viral oncogene homolog A GBrowse link 1 227,928,092 227,938,571 RGD:2298860
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 GBrowse link 10 76,234,192 76,278,394 RGD:1624291
RGD:8554230
G Socs1 suppressor of cytokine signaling 1 GBrowse link 10 3,782,936 3,783,574 RGD:1600115
RGD:1624291
G Socs3 suppressor of cytokine signaling 3 GBrowse link 10 106,611,459 106,616,694 RGD:1600115
RGD:1624291
G Tsc1 tuberous sclerosis 1 GBrowse link 3 12,570,765 12,619,753 RGD:1600115
G Tsc2 tuberous sclerosis 2 GBrowse link 10 13,778,990 13,813,725 RGD:1600115
G Tsc2_v1 tuberous sclerosis 2, variant 1 RGD:1600115
G Tsc2_v2 tuberous sclerosis 2, variant 2 RGD:1600115
G Ybx1 Y box binding protein 1 GBrowse link 5 142,132,028 142,152,551 RGD:727501
positive regulation of insulin receptor signaling pathway term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adipor1 adiponectin receptor 1 GBrowse link 13 56,297,143 56,316,898 RGD:2317907
G Fam132a family with sequence similarity 132, member A GBrowse link 5 176,866,521 176,870,896 RGD:1600115
RGD:1624291
G Igf2 insulin-like growth factor 2 GBrowse link 1 222,722,921 222,733,868 RGD:1600115
RGD:1624291
G Ins1 insulin 1 GBrowse link 1 280,213,615 280,214,182 RGD:1624291
G Irs1 insulin receptor substrate 1 GBrowse link 9 87,782,499 87,835,248 RGD:8553881
G Lep leptin GBrowse link 4 56,085,079 56,099,209 RGD:5128575
G Prkcz protein kinase C, zeta GBrowse link 5 176,116,787 176,228,206 RGD:8553908
G Serpina12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 GBrowse link 6 136,915,080 136,930,199 RGD:1624291
G Sirt1 sirtuin 1 GBrowse link 20 8,139,854 8,159,830 RGD:1600115
RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase GBrowse link 3 158,123,674 158,171,912 RGD:1581139

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 453707
    signaling 58244
      regulation of signaling 20500
        regulation of signal transduction 17696
          regulation of insulin receptor signaling pathway 183
            negative regulation of insulin receptor signaling pathway + 127
            positive regulation of insulin receptor signaling pathway + 37
            regulation of insulin receptor signaling pathway involved in determination of adult lifespan + 0
Path 2
Term Annotations click to browse term
  biological_process 453707
    response to stimulus 107118
      response to chemical 32981
        response to organic substance 18877
          response to organonitrogen compound 3843
            response to peptide 1714
              response to peptide hormone 1618
                response to insulin 1093
                  cellular response to insulin stimulus 877
                    insulin receptor signaling pathway 513
                      regulation of insulin receptor signaling pathway 183
                        negative regulation of insulin receptor signaling pathway + 127
                        positive regulation of insulin receptor signaling pathway + 37
                        regulation of insulin receptor signaling pathway involved in determination of adult lifespan + 0
paths to the root