ONTOLOGY REPORT - ANNOTATIONS
Term: aging
Accession: GO:0007568
browse the term
Definition: A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700).
Synonyms: exact_synonym: ageing
alt_id: GO:0016280
xref_analog: Wikipedia:Aging
aging
G
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
IEP
10
95,361,338
95,381,455
RGD:6893473
RGD
G
Ada
adenosine deaminase
IEP
3
154,636,530
154,660,637
RGD:1624293
RGD
G
Adh4
alcohol dehydrogenase 4 (class II), pi polypeptide
IEP
2
235,952,313
235,970,671
RGD:5129089
RGD
G
Adh5
alcohol dehydrogenase 5 (class III), chi polypeptide
IEP
2
235,979,108
235,991,515
RGD:5129089
RGD
G
Adm
adrenomedullin
IEP
1
168,380,255
168,382,426
RGD:1625311
RGD
G
Adm
adrenomedullin
IEP
1
168,380,255
168,382,426
RGD:2325638
RGD
G
Adra1a
adrenoceptor alpha 1A
IDA
15
46,173,429
46,263,198
RGD:1625777
RGD
G
Adra1a
adrenoceptor alpha 1A
IDA
15
46,173,429
46,263,198
RGD:5688350
RGD
G
Adra1d
adrenoceptor alpha 1D
IDA
3
119,279,974
119,295,985
RGD:5688350
RGD
G
Adrb1
adrenoceptor beta 1
IEP
1
263,025,655
263,027,055
RGD:5129117
RGD
G
Adrb3
adrenoceptor beta 3
IEP
16
69,163,620
69,166,384
RGD:2313169
RGD
G
Adrbk1
adrenergic, beta, receptor kinase 1
IEP
1
206,873,002
206,892,868
RGD:1582266
RGD
G
Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
IEP
19
54,738,556
54,750,349
RGD:5129178
RGD
G
Agtr1a
angiotensin II receptor, type 1a
IEP
17
40,629,318
40,684,982
RGD:5129178
RGD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
IDA
6
137,640,482
137,657,552
RGD:5509106
RGD
G
Aldh3a1
aldehyde dehydrogenase 3 family, member A1
IEP
10
47,365,195
47,374,880
RGD:2300311
RGD
G
Aldoc
aldolase C, fructose-bisphosphate
IDA
10
64,308,826
64,312,415
RGD:2301137
RGD
G
Alox12
arachidonate 12-lipoxygenase
IEP
10
57,080,603
57,092,874
RGD:2302179
RGD
G
Amfr
autocrine motility factor receptor, E3 ubiquitin protein ligase
IEP
19
11,434,553
11,467,592
RGD:1643424
RGD
G
Amh
anti-Mullerian hormone
IEP
7
10,417,325
10,419,673
RGD:2315641
RGD
G
Aoc3
amine oxidase, copper containing 3
IEP
10
90,357,094
90,365,040
RGD:2313935
RGD
G
Apaf1
apoptotic peptidase activating factor 1
IEP
7
27,932,908
28,020,533
RGD:2325740
RGD
G
Apex1
APEX nuclease (multifunctional DNA repair enzyme) 1
IDA
15
26,904,124
26,906,224
RGD:2315679
RGD
G
Apod
apolipoprotein D
IEP
RGD:2311181
RGD
G
Apoe
apolipoprotein E
IDA
1
79,003,634
79,006,387
RGD:2317724
RGD
G
Aqp2
aquaporin 2 (collecting duct)
IEP
7
138,325,855
138,330,891
RGD:2313133
RGD
G
Arg1
arginase, liver
IEP
1
20,998,894
21,011,275
RGD:4143182
RGD
G
Asl
argininosuccinate lyase
IEP
12
27,702,882
27,720,230
RGD:4140929
RGD
G
Ass1
argininosuccinate synthase 1
IEP
3
10,578,717
10,622,332
RGD:4140929
RGD
G
Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
IEP
7
36,493,661
36,600,280
RGD:2317748
RGD
G
Atp5g3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
IEP
3
56,511,747
56,514,204
RGD:2301244
RGD
G
Atp6ap1
ATPase, H+ transporting, lysosomal accessory protein 1
IEP
X
160,306,354
160,313,434
RGD:2301245
RGD
G
Aurkb
aurora kinase B
IEP
10
55,798,710
55,804,367
RGD:2315123
RGD
G
Bak1
BCL2-antagonist/killer 1
IEP
20
5,255,954
5,264,593
RGD:2316112
RGD
G
Bcl2
B-cell CLL/lymphoma 2
IEP
13
12,730,736
12,905,108
RGD:2293079
RGD
G
Bglap
bone gamma-carboxyglutamate (gla) protein
IEP
2
180,482,313
180,483,290
RGD:6483558
RGD
G
C1qb
complement component 1, q subcomponent, B chain
IEP
5
155,647,524
155,653,074
RGD:1599511
RGD
G
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
IEP
16
5,383,259
5,703,361
RGD:6906923
RGD
G
Cacybp
calcyclin binding protein
IEP
13
75,623,161
75,633,644
RGD:2326112
RGD
G
Calca
calcitonin-related polypeptide alpha
IEP
1
172,686,168
172,691,061
RGD:2314033
RGD
G
Canx
calnexin
IEP
10
35,850,944
35,883,494
RGD:2313153
RGD
G
Capn10
calpain 10
IDA
RGD:2317923
RGD
G
Casp12
caspase 12
IEP
8
2,082,933
2,110,511
RGD:2311469
RGD
G
Casp2
caspase 2
IEP
4
70,029,728
70,047,164
RGD:4107079
RGD
G
Casp7
caspase 7
IEP
1
262,689,300
262,721,591
RGD:2311469
RGD
G
Casp9
caspase 9, apoptosis-related cysteine peptidase
IEP
5
160,704,234
160,721,796
RGD:2311469
RGD
G
Cast
calpastatin
IEP
2
1,495,048
1,608,477
RGD:5509820
RGD
G
Cat
catalase
IEP
3
88,654,077
88,686,212
RGD:5130205
RGD
G
Ccl2
chemokine (C-C motif) ligand 2
IEP
10
70,256,263
70,258,061
RGD:4891435
RGD
G
Ccl5
chemokine (C-C motif) ligand 5
IEP
10
71,605,791
71,610,330
RGD:2307163
RGD
G
Ccr5
chemokine (C-C motif) receptor 5
IEP
8
128,907,157
128,912,272
RGD:2307163
RGD
G
Cd86
CD86 molecule
IEP
11
66,215,233
66,238,882
RGD:2313439
RGD
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISO
5
108,908,749
108,916,380
RGD:1624291
RGD
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
IEP
5
108,908,749
108,916,380
RGD:1358479
RGD
G
Ciita
class II, major histocompatibility complex, transactivator
IEP
10
5,087,174
5,133,418
RGD:2313439
RGD
G
Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
IEP
10
89,519,421
89,525,978
RGD:6483356
RGD
G
Cnr1
cannabinoid receptor 1 (brain)
IMP
5
50,427,173
50,445,471
RGD:2314647
RGD
G
Cp
ceruloplasmin (ferroxidase)
IEP
2
105,086,278
105,135,367
RGD:1599628
RGD
G
Crp
C-reactive protein, pentraxin-related
IEP
13
88,702,243
88,703,153
RGD:6482314
RGD
G
Cryab
crystallin, alpha B
IEP
8
54,107,824
54,111,502
RGD:2303634
RGD
G
Ctc1
CTS telomere maintenance complex component 1
ISO
10
55,768,182
55,788,836
RGD:1624291
RGD
G
Ctnna1
catenin (cadherin-associated protein), alpha 1, 102kDa
IEP
18
27,629,915
27,769,360
RGD:2289805
RGD
G
Ctsc
cathepsin C
IEP
1
144,629,802
144,661,183
RGD:1599647
RGD
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
IEP
8
61,462,207
61,468,237
RGD:5147748
RGD
G
Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
IDA
RGD:2307323
RGD
G
Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
IEP
1
81,345,425
81,359,415
RGD:2301454
RGD
G
Cyp3a23/3a1
cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1
IEP
12
9,567,120
9,595,974
RGD:1625392
RGD
G
Dcn
decorin
IEP
7
35,004,234
35,045,191
RGD:2311426
RGD
G
Ddit3
DNA-damage inducible transcript 3
IEP
7
67,247,749
67,252,571
RGD:1299136
RGD
G
Dld
dihydrolipoamide dehydrogenase
IEP
6
49,185,188
49,205,894
RGD:2306416
RGD
G
Dmd
dystrophin
IEP
X
71,501,362
71,671,414
RGD:6771366
RGD
G
Ednra
endothelin receptor type A
IEP
19
32,042,366
32,108,153
RGD:4892581
RGD
G
Ednrb
endothelin receptor type B
IEP
15
87,893,141
87,898,700
RGD:4892600
RGD
G
Eif5a
eukaryotic translation initiation factor 5A
IEP
10
56,760,289
56,764,689
RGD:2308860
RGD
G
Eno3
enolase 3, beta, muscle
IEP
10
57,536,965
57,542,317
RGD:2301762
RGD
G
Epo
erythropoietin
IEP
12
19,551,768
19,555,208
RGD:2313640
RGD
G
Ercc2
excision repair cross-complementing rodent repair deficiency, complementation group 2
ISO
RGD:1624291
RGD
G
Ercc2
excision repair cross-complementing rodent repair deficiency, complementation group 2
ISO
RGD:1624291
RGD
G
Ercc2
excision repair cross-complementing rodent repair deficiency, complementation group 2
ISO
RGD:1624291
RGD
G
Ercc2
excision repair cross-complementing rodent repair deficiency, complementation group 2
IEA
RGD:1600115
ENSEMBL
G
F3
coagulation factor III (thromboplastin, tissue factor)
IEP
2
218,371,050
218,382,645
RGD:2313773
RGD
G
Fads1
fatty acid desaturase 1
IEP
1
212,670,792
212,685,718
RGD:1625420
RGD
G
Fas
Fas (TNF receptor superfamily, member 6)
IEP
1
238,259,443
238,274,745
RGD:1600330
RGD
G
Fos
FBJ osteosarcoma oncogene
IEP
6
109,559,135
109,562,001
RGD:2293789
RGD
G
Fosl2
fos-like antigen 2
IEP
RGD:2293789
RGD
G
Foxg1
forkhead box G1
IEP
6
69,217,672
69,220,482
RGD:2314183
RGD
G
Furin
furin (paired basic amino acid cleaving enzyme)
IEP
1
136,209,969
136,222,057
RGD:1582625
RGD
G
Gfra1
GDNF family receptor alpha 1
IEP
1
264,614,329
264,875,486
RGD:6480089
RGD
G
Ggt1
gamma-glutamyltransferase 1
IEP
RGD:2315578
RGD
G
Gnao1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
IDA
19
11,472,083
11,623,600
RGD:2302009
RGD
G
Gpx1
glutathione peroxidase 1
IEP
RGD:2306622
RGD
G
Gpx4
glutathione peroxidase 4
IEP
7
11,162,521
11,165,318
RGD:2306622
RGD
G
Grb2
growth factor receptor bound protein 2
IPI
10
105,722,014
105,818,649
RGD:1643178
RGD
G
Gsn
gelsolin
IEP
3
14,360,245
14,386,313
RGD:1304020
RGD
G
Gss
glutathione synthetase
IEP
3
146,057,517
146,087,820
RGD:2301454
RGD
G
Gsta1
glutathione S-transferase alpha 1
IEP
9
20,051,501
20,068,146
RGD:2306661
RGD
G
Gsta2
glutathione S-transferase alpha 2
IEP
8
83,299,249
83,312,958
RGD:2306661
RGD
G
Gstm2
glutathione S-transferase mu 2
IEP
2
203,549,022
203,553,380
RGD:2302179
RGD
G
Hcn2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
IEP
7
11,485,257
11,503,614
RGD:2316624
RGD
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
IEP
2
27,127,504
27,149,580
RGD:2317945
RGD
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
IEP
2
27,127,504
27,149,580
RGD:5508699
RGD
G
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IEP
15
55,463,743
55,532,293
RGD:1624378
RGD
G
Igfbp2
insulin-like growth factor binding protein 2
IEP
9
71,966,877
71,994,211
RGD:1626514
RGD
G
Il15
interleukin 15
IEP
19
27,487,268
27,498,973
RGD:1626613
RGD
G
Il1b
interleukin 1 beta
IMP
3
116,964,422
116,970,867
RGD:1626647
RGD
G
Il6
interleukin 6
IEP
4
456,799
461,376
RGD:2306935
RGD
G
Ireb2
iron responsive element binding protein 2
IEP
8
58,433,218
58,477,305
RGD:6893272
RGD
G
Itgb2
integrin, beta 2
IEP
20
11,446,521
11,485,009
RGD:6482194
RGD
G
Jun
jun proto-oncogene
IEP
5
115,358,166
115,361,259
RGD:2293789
RGD
G
Jund
jun D proto-oncogene
IEP
16
19,239,694
19,241,529
RGD:2293789
RGD
G
Kl
Klotho
TAS
12
3,732,712
3,772,371
RGD:633145
RGD
G
Kl
Klotho
ISO
12
3,732,712
3,772,371
RGD:1624291
RGD
G
Kl
Klotho
ISO
12
3,732,712
3,772,371
RGD:1624291
RGD
G
Lck
lymphocyte-specific protein tyrosine kinase
IEP
5
148,707,505
148,718,296
RGD:1600226
RGD
G
Ldlr
low density lipoprotein receptor
IEP
8
20,824,040
20,846,920
RGD:1581819
RGD
G
Lonp1
lon peptidase 1, mitochondrial
IEP
RGD:2303495
RGD
G
Lrp1
low density lipoprotein receptor-related protein 1
IEP
7
67,520,575
67,601,549
RGD:1625018
RGD
G
Lrp2
low density lipoprotein receptor-related protein 2
IEP
3
51,563,764
51,724,478
RGD:1641828
RGD
G
Madcam1
mucosal vascular addressin cell adhesion molecule 1
IEP
7
11,553,219
11,556,621
RGD:2311548
RGD
G
Mgea5
meningioma expressed antigen 5 (hyaluronidase)
IEP
1
250,966,386
251,000,363
RGD:2305952
RGD
G
Mif
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
IEP
20
13,191,986
13,192,851
RGD:1641992
RGD
G
Mmp2
matrix metallopeptidase 2
IEP
19
15,246,036
15,275,061
RGD:2290430
RGD
G
Mmp9
matrix metallopeptidase 9
IEP
3
155,985,473
155,993,433
RGD:2290430
RGD
G
Mpo
myeloperoxidase
IEP
10
76,085,872
76,097,012
RGD:2317972
RGD
G
Msra
methionine sulfoxide reductase A
IEP
15
43,509,775
43,756,283
RGD:70794
RGD
G
Msra
methionine sulfoxide reductase A
IDA
15
43,509,775
43,756,283
RGD:2324653
RGD
G
Mt-atp6
mitochondrially encoded ATP synthase 6
IEP
MT
7,919
8,599
RGD:5490295
RGD
G
Mt-co1
mitochondrially encoded cytochrome c oxidase I
IEP
MT
5,323
6,867
RGD:2302303
RGD
G
Mt-nd4
mitochondrially encoded NADH dehydrogenase 4
IDA
MT
10,160
11,537
RGD:2302306
RGD
G
Nat2
N-acetyltransferase 2 (arylamine N-acetyltransferase)
IEP
16
23,855,555
23,876,531
RGD:5131598
RGD
G
Ncam1
neural cell adhesion molecule 1
IDA
8
52,822,350
53,120,572
RGD:2326009
RGD
G
Ncf2
neutrophil cytosolic factor 2
IEP
13
67,806,516
67,834,105
RGD:2292095
RGD
G
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100
IEP
1
251,521,559
251,527,815
RGD:2302396
RGD
G
Ngf
nerve growth factor (beta polypeptide)
IEP
2
197,621,726
197,632,960
RGD:5144122
RGD
G
Nos1
nitric oxide synthase 1, neuronal
IEP
12
39,812,500
39,869,484
RGD:1642135
RGD
G
Nos2
nitric oxide synthase 2, inducible
IEP
10
65,036,884
65,072,453
RGD:2313213
RGD
G
Nos3
nitric oxide synthase 3, endothelial cell
IEP
4
6,158,847
6,179,441
RGD:2292095
RGD
G
Nox4
NADPH oxidase 4
IEP
1
143,415,816
143,603,554
RGD:2324660
RGD
G
Nqo1
NAD(P)H dehydrogenase, quinone 1
IEP
19
37,251,147
37,266,040
RGD:5133233
RGD
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
IEP
18
32,371,496
32,459,145
RGD:4892124
RGD
G
Ntrk1
neurotrophic tyrosine kinase, receptor, type 1
IEP
2
179,838,740
179,855,545
RGD:5144122
RGD
G
Ntrk1
neurotrophic tyrosine kinase, receptor, type 1
IEP
2
179,838,740
179,855,545
RGD:5684347
RGD
G
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
IEP
17
11,494,463
11,811,654
RGD:5684924
RGD
G
P2ry1
purinergic receptor P2Y, G-protein coupled, 1
IEP
2
150,460,361
150,465,855
RGD:2316735
RGD
G
P2ry2
purinergic receptor P2Y, G-protein coupled, 2
IEP
1
158,440,018
158,454,213
RGD:2316735
RGD
G
Pax2
paired box 2
IEP
1
249,804,055
249,895,306
RGD:2316745
RGD
G
Pde4d
phosphodiesterase 4D, cAMP-specific
IEA
2
40,196,097
41,311,012
RGD:1600115
ENSEMBL
G
Pde4d
phosphodiesterase 4D, cAMP-specific
ISO
2
40,196,097
41,311,012
RGD:1624291
RGD
G
Pebp1
phosphatidylethanolamine binding protein 1
IEP
12
40,491,393
40,495,593
RGD:2302808
RGD
G
Phox2a
paired-like homeobox 2a
IEP
1
159,273,524
159,312,136
RGD:1579826
RGD
G
Pik3r1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
IEP
2
32,602,673
32,675,350
RGD:1625220
RGD
G
Pla2g4a
phospholipase A2, group IVA (cytosolic, calcium-dependent)
IEP
13
64,135,729
64,280,815
RGD:1642464
RGD
G
Polg
polymerase (DNA directed), gamma
ISO
1
135,197,075
135,212,178
RGD:1624291
RGD
G
Polg
polymerase (DNA directed), gamma
IEA
1
135,197,075
135,212,178
RGD:1600115
ENSEMBL
G
Prkca
protein kinase C, alpha
IEP
10
97,367,196
97,638,910
RGD:2298670
RGD
G
Prkcd
protein kinase C, delta
IEP
16
5,954,218
5,975,743
RGD:1642546
RGD
G
Prkcq
protein kinase C, theta
IEP
17
78,486,998
78,566,741
RGD:1625620
RGD
G
Pten
phosphatase and tensin homolog
IEP
1
236,771,027
236,837,261
RGD:2292534
RGD
G
Ptgs1
prostaglandin-endoperoxide synthase 1
IEP
3
15,343,832
15,365,412
RGD:2300265
RGD
G
Pth1r
parathyroid hormone 1 receptor
IEP
8
115,099,763
115,119,362
RGD:1599981
RGD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
IEP
1
208,262,669
208,273,148
RGD:2298786
RGD
G
Retn
resistin
IEP
12
2,499,630
2,501,370
RGD:7207255
RGD
G
Rnpep
arginyl aminopeptidase (aminopeptidase B)
IEP
13
48,267,923
48,286,295
RGD:2325947
RGD
G
Rpn2
ribophorin II
IEP
3
147,976,544
148,023,743
RGD:2325966
RGD
G
Rps6kb1
ribosomal protein S6 kinase, polypeptide 1
IEP
10
76,657,024
76,698,088
RGD:1643019
RGD
G
Rtn4
reticulon 4
IEP
14
110,725,089
110,772,578
RGD:2314960
RGD
G
Rxra
retinoid X receptor alpha
IEP
3
6,605,782
6,689,224
RGD:1643118
RGD
G
Scap
SREBF chaperone
IEP
8
114,706,479
114,761,342
RGD:1581819
RGD
G
Serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
IEP
X
126,739,203
126,744,763
RGD:1600136
RGD
G
Serpinf1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
IEP
10
62,713,441
62,739,444
RGD:2312350
RGD
G
Shc1
SHC (Src homology 2 domain containing) transforming protein 1
IPI
2
181,616,581
181,628,144
RGD:1643178
RGD
G
Si
sucrase-isomaltase (alpha-glucosidase)
IEP
2
163,520,975
163,601,280
RGD:1625553
RGD
G
Sin3a
SIN3 transcription regulator homolog A (yeast)
IDA
8
60,832,595
60,884,764
RGD:2306468
RGD
G
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
IDA
1
265,789,917
265,824,551
RGD:2317339
RGD
G
Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
IEP
3
149,342,399
149,347,124
RGD:2324692
RGD
G
Slc34a2
solute carrier family 34 (sodium phosphate), member 2
IEP
14
62,660,006
62,679,311
RGD:2311313
RGD
G
Slc6a3
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
IEP
1
30,516,568
30,557,540
RGD:1625669
RGD
G
Snca
synuclein, alpha (non A4 component of amyloid precursor)
IEP
4
89,613,731
89,722,807
RGD:6218973
RGD
G
Socs2
suppressor of cytokine signaling 2
IEP
7
32,605,714
32,608,323
RGD:2298927
RGD
G
Socs3
suppressor of cytokine signaling 3
IEP
10
107,958,468
107,959,330
RGD:625538
RGD
G
Sod1
superoxide dismutase 1, soluble
ISO
11
29,810,766
29,816,342
RGD:1624291
RGD
G
Sod2
superoxide dismutase 2, mitochondrial
IEP
1
41,862,997
41,870,327
RGD:1625691
RGD
G
Srebf1
sterol regulatory element binding transcription factor 1
IEP
10
46,461,684
46,483,646
RGD:1581819
RGD
G
Srebf2
sterol regulatory element binding transcription factor 2
IEP
7
120,522,511
120,580,212
RGD:1581819
RGD
G
Srr
serine racemase
IEP
10
62,217,481
62,234,831
RGD:2302214
RGD
G
Sult2a1
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
IEP
1
75,632,632
75,708,022
RGD:2317008
RGD
G
Tacr3
tachykinin receptor 3
IEP
2
232,309,015
232,404,964
RGD:2305954
RGD
G
Tfrc
transferrin receptor
IEP
11
69,976,258
69,998,098
RGD:2292027
RGD
G
Tgfb1
transforming growth factor, beta 1
IEP
1
80,894,705
80,911,020
RGD:2302033
RGD
G
Tgfb2
transforming growth factor, beta 2
IEP
13
102,718,703
102,818,768
RGD:2302033
RGD
G
Tgfb3
transforming growth factor, beta 3
IEP
6
110,173,443
110,195,215
RGD:2302033
RGD
G
Tgfbr1
transforming growth factor, beta receptor 1
IEP
5
63,976,868
64,034,058
RGD:2302033
RGD
G
Tgfbr2
transforming growth factor, beta receptor II
IEP
8
120,593,595
120,680,453
RGD:2302033
RGD
G
Timp1
TIMP metallopeptidase inhibitor 1
IEP
X
12,542,496
12,547,094
RGD:2290357
RGD
G
Timp2
TIMP metallopeptidase inhibitor 2
IEP
10
108,310,473
108,358,821
RGD:2290357
RGD
G
Timp2
TIMP metallopeptidase inhibitor 2
IEP
10
108,310,473
108,358,821
RGD:2290430
RGD
G
Timp3
TIMP metallopeptidase inhibitor 3
IEP
7
19,677,144
19,727,072
RGD:2290357
RGD
G
Timp3
TIMP metallopeptidase inhibitor 3
IEP
7
19,677,144
19,727,072
RGD:2290430
RGD
G
Top2a
topoisomerase (DNA) II alpha
IEP
10
87,771,337
87,800,960
RGD:2315123
RGD
G
Tp53
tumor protein p53
IEP
10
56,399,721
56,411,150
RGD:2290558
RGD
G
Tspo
translocator protein
IEP
7
121,597,084
121,599,342
RGD:2317163
RGD
G
Tyms
thymidylate synthetase
IEP
9
112,604,912
112,617,706
RGD:2317423
RGD
G
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
IEP
1
157,925,514
157,928,222
RGD:7204432
RGD
G
Ucp3
uncoupling protein 3 (mitochondrial, proton carrier)
IEP
1
157,896,001
157,909,608
RGD:2313527
RGD
G
Vcam1
vascular cell adhesion molecule 1
IEP
2
212,277,654
212,297,376
RGD:2313112
RGD
G
Vdr
vitamin D (1,25- dihydroxyvitamin D3) receptor
IEP
7
136,567,614
136,617,280
RGD:4889988
RGD
G
Vim
vimentin
IEP
17
87,847,280
87,855,763
RGD:6480444
RGD
age-dependent response to oxidative stress
G
Cln8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
ISO
16
79,569,745
79,579,636
RGD:1624291
RGD
G
Cln8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
IEA
16
79,569,745
79,579,636
RGD:1600115
ENSEMBL
G
Coq7
coenzyme Q7 homolog, ubiquinone (yeast)
ISO
1
176,722,271
176,746,436
RGD:1624291
RGD
G
Coq7
coenzyme Q7 homolog, ubiquinone (yeast)
IEA
1
176,722,271
176,746,436
RGD:1600115
ENSEMBL
G
Sod2
superoxide dismutase 2, mitochondrial
ISO
1
41,862,997
41,870,327
RGD:1624291
RGD
age-dependent response to reactive oxygen species
G
Sod2
superoxide dismutase 2, mitochondrial
ISO
1
41,862,997
41,870,327
RGD:1624291
RGD
G
Sod2
superoxide dismutase 2, mitochondrial
ISS
1
41,862,997
41,870,327
RGD:1600115
UniProtKB
age-dependent telomere shortening
G
Terf1
telomeric repeat binding factor (NIMA-interacting) 1
ISO
5
2,556,918
2,586,086
RGD:1624291
RGD
G
Terf1
telomeric repeat binding factor (NIMA-interacting) 1
IEA
5
2,556,918
2,586,086
RGD:1600115
ENSEMBL
cell aging
G
Bcl2
B-cell CLL/lymphoma 2
ISO
13
12,730,736
12,905,108
RGD:1624291
RGD
G
Bcl2
B-cell CLL/lymphoma 2
IEA
13
12,730,736
12,905,108
RGD:1600115
ENSEMBL
G
Bglap
bone gamma-carboxyglutamate (gla) protein
IEP
2
180,482,313
180,483,290
RGD:2316145
RGD
G
Brca2
breast cancer 2, early onset
ISO
12
4,282,952
4,323,693
RGD:1624291
RGD
G
Brca2
breast cancer 2, early onset
IEA
12
4,282,952
4,323,693
RGD:1600115
ENSEMBL
G
Cdk1
cyclin-dependent kinase 1
IDA
20
20,018,044
20,044,030
RGD:2301352
RGD
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISO
5
108,908,749
108,916,380
RGD:1624291
RGD
G
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
IEP
1
12,721,500
12,723,943
RGD:5147849
RGD
G
Dnaja3
DnaJ (Hsp40) homolog, subfamily A, member 3
ISO
10
10,984,721
11,009,374
RGD:1624291
RGD
G
Dnaja3
DnaJ (Hsp40) homolog, subfamily A, member 3
IEA
10
10,984,721
11,009,374
RGD:1600115
ENSEMBL
G
Hras
Harvey rat sarcoma virus oncogene
ISO
1
201,385,705
201,388,987
RGD:1624291
RGD
G
Hras
Harvey rat sarcoma virus oncogene
ISO
1
201,385,705
201,388,987
RGD:1624291
RGD
G
Hsd17b10
hydroxysteroid (17-beta) dehydrogenase 10
IEP
X
41,489,343
41,491,788
RGD:2302236
RGD
G
Htt
huntingtin
ISO
14
81,490,322
81,636,856
RGD:1624291
RGD
G
Htt
huntingtin
IEA
14
81,490,322
81,636,856
RGD:1600115
ENSEMBL
G
Icam1
intercellular adhesion molecule 1
IEP
8
20,040,177
20,051,939
RGD:4145420
RGD
G
Ilk
integrin-linked kinase
IMP
1
163,481,299
163,487,550
RGD:2301768
RGD
G
Met
met proto-oncogene
IEP
4
43,134,183
43,211,355
RGD:2317463
RGD
G
Mif
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
ISO
20
13,191,986
13,192,851
RGD:1624291
RGD
G
Morc3
MORC family CW-type zinc finger 3
ISO
11
34,061,754
34,104,508
RGD:1624291
RGD
G
Morc3
MORC family CW-type zinc finger 3
IEA
11
34,061,754
34,104,508
RGD:1600115
ENSEMBL
G
Nox4
NADPH oxidase 4
ISO
1
143,415,816
143,603,554
RGD:1624291
RGD
G
Nox4
NADPH oxidase 4
ISS
1
143,415,816
143,603,554
RGD:1600115
UniProtKB
G
Npm1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
ISO
10
18,051,990
18,062,714
RGD:1624291
RGD
G
Npm1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
ISS
10
18,051,990
18,062,714
RGD:1600115
UniProtKB
G
Nup62
nucleoporin 62
ISO
1
95,288,019
95,303,545
RGD:1624291
RGD
G
Nup62
nucleoporin 62
IEA
1
95,288,019
95,303,545
RGD:1600115
ENSEMBL
G
Pdcd4
programmed cell death 4
ISO
1
260,183,648
260,202,032
RGD:1624291
RGD
G
Pdcd4
programmed cell death 4
ISS
1
260,183,648
260,202,032
RGD:1600115
UniProtKB
G
Pml
promyelocytic leukemia
ISO
8
62,020,438
62,051,927
RGD:1624291
RGD
G
Pot1b
protection of telomeres 1B
ISO
RGD:1624291
RGD
G
Prelp
proline/arginine-rich end leucine-rich repeat protein
ISO
13
46,863,392
46,874,172
RGD:1624291
RGD
G
Prelp
proline/arginine-rich end leucine-rich repeat protein
IEA
13
46,863,392
46,874,172
RGD:1600115
ENSEMBL
G
Sod1
superoxide dismutase 1, soluble
ISO
11
29,810,766
29,816,342
RGD:1624291
RGD
G
Sod1
superoxide dismutase 1, soluble
ISS
11
29,810,766
29,816,342
RGD:1600115
UniProtKB
G
Tbx2
T-box 2
ISO
10
74,085,203
74,092,988
RGD:1624291
RGD
G
Tbx2
T-box 2
ISO
10
74,085,203
74,092,988
RGD:1624291
RGD
G
Tbx3
T-box 3
ISO
12
38,155,494
38,166,670
RGD:1624291
RGD
G
Tbx3
T-box 3
ISO
12
38,155,494
38,166,670
RGD:1624291
RGD
G
Tbx3
T-box 3
ISO
12
38,155,494
38,166,670
RGD:1624291
RGD
G
Tbx3
T-box 3
ISS
12
38,155,494
38,166,670
RGD:1600115
UniProtKB
G
Tp53
tumor protein p53
ISO
10
56,399,721
56,411,150
RGD:1624291
RGD
G
Tp53
tumor protein p53
ISO
10
56,399,721
56,411,150
RGD:1624291
RGD
G
Tp53
tumor protein p53
ISS
10
56,399,721
56,411,150
RGD:1600115
UniProtKB
G
Tp63
tumor protein p63
ISO
11
76,900,622
77,200,251
RGD:1624291
RGD
G
Tp63
tumor protein p63
IEA
11
76,900,622
77,200,251
RGD:1600115
ENSEMBL
G
Wrn
Werner syndrome, RecQ helicase-like
ISO
16
62,535,144
62,668,700
RGD:1624291
RGD
G
Zmiz1
zinc finger, MIZ-type containing 1
ISO
16
1,037,882
1,245,259
RGD:1624291
RGD
G
Zmiz1
zinc finger, MIZ-type containing 1
IEA
16
1,037,882
1,245,259
RGD:1600115
ENSEMBL
cellular senescence
G
Calr
calreticulin
ISO
19
24,964,775
24,969,670
RGD:1624291
RGD
G
Calr
calreticulin
ISO
19
24,964,775
24,969,670
RGD:1624291
RGD
G
Calr
calreticulin
IEA
19
24,964,775
24,969,670
RGD:1600115
ENSEMBL
G
Calr
calreticulin
IEA
19
24,964,775
24,969,670
RGD:1600115
ENSEMBL
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
ISO
20
7,376,325
7,386,778
RGD:1624291
RGD
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
IEA
20
7,376,325
7,386,778
RGD:1600115
ENSEMBL
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISO
5
108,908,749
108,916,380
RGD:1624291
RGD
G
Hras
Harvey rat sarcoma virus oncogene
ISO
1
201,385,705
201,388,987
RGD:1624291
RGD
G
Hras
Harvey rat sarcoma virus oncogene
IEA
1
201,385,705
201,388,987
RGD:1600115
ENSEMBL
G
Id2
inhibitor of DNA binding 2
ISO
6
42,781,476
42,783,307
RGD:1624291
RGD
G
Id2
inhibitor of DNA binding 2
ISS
6
42,781,476
42,783,307
RGD:1600115
UniProtKB
G
Kat6a
K(lysine) acetyltransferase 6A
ISO
16
73,553,868
73,634,794
RGD:1624291
RGD
G
Kat6a
K(lysine) acetyltransferase 6A
ISS
16
73,553,868
73,634,794
RGD:1600115
UniProtKB
G
Map2k1
mitogen activated protein kinase kinase 1
ISO
8
68,379,074
68,451,554
RGD:1624291
RGD
G
Map2k1
mitogen activated protein kinase kinase 1
IEA
8
68,379,074
68,451,554
RGD:1600115
ENSEMBL
G
Nsmce2
non-SMC element 2, MMS21 homolog (S. cerevisiae)
ISO
7
96,167,635
96,393,594
RGD:1624291
RGD
G
Nsmce2
non-SMC element 2, MMS21 homolog (S. cerevisiae)
ISS
7
96,167,635
96,393,594
RGD:1600115
UniProtKB
G
Opa1
optic atrophy 1
ISO
11
73,005,470
73,058,136
RGD:1624291
RGD
G
Pml
promyelocytic leukemia
ISO
8
62,020,438
62,051,927
RGD:1624291
RGD
G
Pml
promyelocytic leukemia
ISO
8
62,020,438
62,051,927
RGD:1624291
RGD
G
Pml
promyelocytic leukemia
ISO
8
62,020,438
62,051,927
RGD:1624291
RGD
G
Prkcd
protein kinase C, delta
ISO
16
5,954,218
5,975,743
RGD:1624291
RGD
G
Prkcd
protein kinase C, delta
IEA
16
5,954,218
5,975,743
RGD:1600115
ENSEMBL
G
RGD1305645
similar to RIKEN cDNA 1500015O10
ISO
9
42,931,051
42,950,605
RGD:1624291
RGD
G
RGD1305645
similar to RIKEN cDNA 1500015O10
IEA
9
42,931,051
42,950,605
RGD:1600115
ENSEMBL
G
Smc5
structural maintenance of chromosomes 5
IEA
1
226,494,137
226,566,143
RGD:1600115
ENSEMBL
G
Smc5
structural maintenance of chromosomes 5
ISO
1
226,494,137
226,566,143
RGD:1624291
RGD
G
Smc6
structural maintenance of chromosomes 6
IEA
6
34,710,177
34,763,158
RGD:1600115
ENSEMBL
G
Smc6
structural maintenance of chromosomes 6
ISO
6
34,710,177
34,763,158
RGD:1624291
RGD
G
Srf
serum response factor (c-fos serum response element-binding transcription factor)
ISO
9
9,788,378
9,797,639
RGD:1624291
RGD
G
Tbx2
T-box 2
ISO
10
74,085,203
74,092,988
RGD:1624291
RGD
G
Tbx3
T-box 3
ISO
12
38,155,494
38,166,670
RGD:1624291
RGD
G
Tbx3
T-box 3
ISS
12
38,155,494
38,166,670
RGD:1600115
UniProtKB
chronological cell aging
G
Eng
endoglin
ISO
RGD:1624291
RGD
G
Serpine1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
ISO
12
20,931,996
20,942,374
RGD:1624291
RGD
G
Serpine1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
IEA
12
20,931,996
20,942,374
RGD:1600115
ENSEMBL
determination of adult lifespan
G
Bbc3
Bcl-2 binding component 3
ISO
RGD:1624291
RGD
G
Coq7
coenzyme Q7 homolog, ubiquinone (yeast)
ISO
1
176,722,271
176,746,436
RGD:1624291
RGD
G
Coq7
coenzyme Q7 homolog, ubiquinone (yeast)
IEA
1
176,722,271
176,746,436
RGD:1600115
ENSEMBL
G
Ercc5
excision repair cross-complementing rodent repair deficiency, complementation group 5
ISO
9
43,248,023
43,293,196
RGD:1624291
RGD
G
Ercc5
excision repair cross-complementing rodent repair deficiency, complementation group 5
IEA
9
43,248,023
43,293,196
RGD:1600115
ENSEMBL
G
Ghrhr
growth hormone releasing hormone receptor
ISO
4
84,135,530
84,148,503
RGD:1624291
RGD
G
Ghrhr
growth hormone releasing hormone receptor
IEA
4
84,135,530
84,148,503
RGD:1600115
ENSEMBL
G
Htt
huntingtin
ISO
14
81,490,322
81,636,856
RGD:1624291
RGD
G
Htt
huntingtin
ISO
14
81,490,322
81,636,856
RGD:1624291
RGD
G
Htt
huntingtin
IEA
14
81,490,322
81,636,856
RGD:1600115
ENSEMBL
G
Ide
insulin degrading enzyme
ISO
1
241,547,869
241,646,052
RGD:1624291
RGD
G
Ide
insulin degrading enzyme
IEA
1
241,547,869
241,646,052
RGD:1600115
ENSEMBL
G
Inpp5d
inositol polyphosphate-5-phosphatase D
ISO
9
86,576,742
86,682,240
RGD:1624291
RGD
G
Inpp5d
inositol polyphosphate-5-phosphatase D
IEA
9
86,576,742
86,682,240
RGD:1600115
ENSEMBL
G
Lrrk2
leucine-rich repeat kinase 2
ISO
7
130,105,902
130,267,747
RGD:1624291
RGD
G
Msh2
mutS homolog 2 (E. coli)
ISO
6
11,199,906
11,258,350
RGD:1624291
RGD
G
Msh2
mutS homolog 2 (E. coli)
IEA
6
11,199,906
11,258,350
RGD:1600115
ENSEMBL
G
Msh6
mutS homolog 6 (E. coli)
ISO
6
11,525,292
11,542,592
RGD:1624291
RGD
G
Msh6
mutS homolog 6 (E. coli)
ISO
6
11,525,292
11,542,592
RGD:1624291
RGD
G
Pou1f1
POU class 1 homeobox 1
ISO
11
2,959,383
2,980,545
RGD:1624291
RGD
G
Pou1f1
POU class 1 homeobox 1
IEA
11
2,959,383
2,980,545
RGD:1600115
ENSEMBL
G
Tfcp2l1
transcription factor CP2-like 1
ISO
13
31,288,228
31,401,482
RGD:1624291
RGD
G
Tfcp2l1
transcription factor CP2-like 1
IEA
13
31,288,228
31,401,482
RGD:1600115
ENSEMBL
G
Tp53
tumor protein p53
ISO
10
56,399,721
56,411,150
RGD:1624291
RGD
menopause
G
Cat
catalase
IEP
3
88,654,077
88,686,212
RGD:5130890
RGD
multicellular organismal aging
G
Acan
aggrecan
IEP
1
134,787,341
134,848,992
RGD:2315752
RGD
G
Adrbk2
adrenergic, beta, receptor kinase 2
IEP
RGD:5685607
RGD
G
Cisd2
CDGSH iron sulfur domain 2
ISO
2
232,902,533
232,927,338
RGD:1624291
RGD
G
Cisd2
CDGSH iron sulfur domain 2
IEA
2
232,902,533
232,927,338
RGD:1600115
ENSEMBL
G
Ctsl1
cathepsin L1
IEP
17
6,288,013
6,294,174
RGD:2315581
RGD
G
Dbh
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
IEP
3
6,052,706
6,069,826
RGD:5129682
RGD
G
Ddc
dopa decarboxylase (aromatic L-amino acid decarboxylase)
IEP
14
92,698,636
92,788,635
RGD:5129108
RGD
G
Edn1
endothelin 1
IEP
17
28,303,886
28,309,775
RGD:4144863
RGD
G
Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1
ISO
1
78,711,249
78,722,474
RGD:1624291
RGD
G
Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1
IEA
1
78,711,249
78,722,474
RGD:1600115
ENSEMBL
G
Helt
helt bHLH transcription factor
IEA
16
49,271,310
49,273,233
RGD:1600115
ENSEMBL
G
Helt
helt bHLH transcription factor
ISO
16
49,271,310
49,273,233
RGD:1624291
RGD
G
Hyal2
hyaluronoglucosaminidase 2
IEA
8
112,817,001
112,820,693
RGD:1600115
ENSEMBL
G
Hyal2
hyaluronoglucosaminidase 2
ISO
8
112,817,001
112,820,693
RGD:1624291
RGD
G
Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
ISO
2
26,295,710
26,296,123
RGD:1624291
RGD
G
Nr5a1
nuclear receptor subfamily 5, group A, member 1
ISO
3
18,498,913
18,519,738
RGD:1624291
RGD
G
Nr5a1
nuclear receptor subfamily 5, group A, member 1
IEA
3
18,498,913
18,519,738
RGD:1600115
ENSEMBL
G
Sec63
SEC63 homolog (S. cerevisiae)
ISO
20
46,669,125
46,738,077
RGD:1624291
RGD
G
Serp1
stress-associated endoplasmic reticulum protein 1
ISO
2
147,866,072
147,870,096
RGD:1624291
RGD
G
Serp1
stress-associated endoplasmic reticulum protein 1
IEA
2
147,866,072
147,870,096
RGD:1600115
ENSEMBL
G
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
ISO
3
87,870,558
87,992,401
RGD:1624291
RGD
G
Spef2
sperm flagellar 2
ISO
2
59,163,063
59,333,207
RGD:1624291
RGD
G
Terc
telomerase RNA component
ISO
2
117,234,446
117,234,833
RGD:1624291
RGD
G
Th
tyrosine hydroxylase
IEP
1
203,164,253
203,171,506
RGD:5129108
RGD
G
Tp63
tumor protein p63
ISO
11
76,900,622
77,200,251
RGD:1624291
RGD
G
Tp63
tumor protein p63
IEA
11
76,900,622
77,200,251
RGD:1600115
ENSEMBL
G
Wrn
Werner syndrome, RecQ helicase-like
ISO
16
62,535,144
62,668,700
RGD:1624291
RGD
G
Wrn
Werner syndrome, RecQ helicase-like
ISO
16
62,535,144
62,668,700
RGD:1624291
RGD
negative regulation of cell aging
G
Foxm1
forkhead box M1
ISO
4
165,383,666
165,394,688
RGD:1624291
RGD
G
Foxm1
forkhead box M1
IEA
4
165,383,666
165,394,688
RGD:1600115
ENSEMBL
G
Fzr1
fizzy/cell division cycle 20 related 1 (Drosophila)
IEA
7
9,816,491
9,829,006
RGD:1600115
ENSEMBL
G
March5
membrane-associated ring finger (C3HC4) 5
IEA
1
241,475,394
241,495,500
RGD:1600115
ENSEMBL
G
March5
membrane-associated ring finger (C3HC4) 5
ISO
1
241,475,394
241,495,500
RGD:1624291
RGD
G
Mif
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
ISO
20
13,191,986
13,192,851
RGD:1624291
RGD
G
Pten
phosphatase and tensin homolog
ISO
1
236,771,027
236,837,261
RGD:1624291
RGD
G
Pten
phosphatase and tensin homolog
IEA
1
236,771,027
236,837,261
RGD:1600115
ENSEMBL
G
Wnt1
wingless-type MMTV integration site family, member 1
ISO
7
137,557,836
137,561,883
RGD:1624291
RGD
G
Wnt1
wingless-type MMTV integration site family, member 1
IEA
7
137,557,836
137,561,883
RGD:1600115
ENSEMBL
negative regulation of cellular senescence
G
Cdk6
cyclin-dependent kinase 6
ISO
4
27,362,656
27,618,006
RGD:1624291
RGD
G
Cdk6
cyclin-dependent kinase 6
IEA
4
27,362,656
27,618,006
RGD:1600115
ENSEMBL
G
Sirt1
sirtuin 1
IEA
20
25,675,302
25,686,494
RGD:1600115
ENSEMBL
G
Sirt1
sirtuin 1
ISO
20
25,675,302
25,686,494
RGD:1624291
RGD
G
Twist1
twist basic helix-loop-helix transcription factor 1
ISO
6
52,605,869
52,607,863
RGD:1624291
RGD
G
Twist1
twist basic helix-loop-helix transcription factor 1
IEA
6
52,605,869
52,607,863
RGD:1600115
ENSEMBL
G
Zkscan3
zinc finger with KRAB and SCAN domains 3
ISO
17
50,862,534
50,901,252
RGD:1624291
RGD
nucleolar fragmentation
G
Zfp354a
zinc finger protein 354A
IMP
10
36,654,406
36,665,659
RGD:1303369
RGD
oncogene-induced senescence
G
Hmga1
high mobility group AT-hook 1
ISS
20
5,769,052
5,772,269
RGD:1600115
UniProtKB
G
Hmga2
high mobility group AT-hook 2
ISO
7
59,638,555
59,753,791
RGD:1624291
RGD
G
Hmga2
high mobility group AT-hook 2
ISS
7
59,638,555
59,753,791
RGD:1600115
UniProtKB
organ senescence
G
Ctgf
connective tissue growth factor
IEP
1
21,327,099
21,330,215
RGD:2314657
RGD
G
Pdx1
pancreatic and duodenal homeobox 1
IEP
RGD:2311175
RGD
oxidative stress-induced premature senescence
G
Pla2r1
phospholipase A2 receptor 1
ISO
3
42,121,966
42,250,869
RGD:1624291
RGD
G
Pla2r1
phospholipase A2 receptor 1
ISS
3
42,121,966
42,250,869
RGD:1600115
UniProtKB
G
Tp53
tumor protein p53
ISO
10
56,399,721
56,411,150
RGD:1624291
RGD
G
Wnt16
wingless-type MMTV integration site family, member 16
IEA
4
48,609,677
48,620,317
RGD:1600115
ENSEMBL
G
Wnt16
wingless-type MMTV integration site family, member 16
ISO
4
48,609,677
48,620,317
RGD:1624291
RGD
positive regulation of cell aging
G
Lmna
lamin A/C
ISO
2
180,595,724
180,616,354
RGD:1624291
RGD
G
Lmna
lamin A/C
IEA
2
180,595,724
180,616,354
RGD:1600115
ENSEMBL
G
Lmna
lamin A/C
ISS
2
180,595,724
180,616,354
RGD:1600115
UniProtKB
G
Tp53
tumor protein p53
ISO
10
56,399,721
56,411,150
RGD:1624291
RGD
positive regulation of cellular senescence
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISO
5
108,908,749
108,916,380
RGD:1624291
RGD
G
Hmga1
high mobility group AT-hook 1
ISS
20
5,769,052
5,772,269
RGD:1600115
UniProtKB
G
Hmga2
high mobility group AT-hook 2
ISO
7
59,638,555
59,753,791
RGD:1624291
RGD
G
Hmga2
high mobility group AT-hook 2
ISS
7
59,638,555
59,753,791
RGD:1600115
UniProtKB
G
Sirt1
sirtuin 1
IEA
20
25,675,302
25,686,494
RGD:1600115
ENSEMBL
G
Sirt1
sirtuin 1
ISO
20
25,675,302
25,686,494
RGD:1624291
RGD
regulation of cellular senescence
G
Nuak1
NUAK family, SNF1-like kinase, 1
ISO
7
21,461,413
21,529,068
RGD:1624291
RGD
G
Nuak1
NUAK family, SNF1-like kinase, 1
IEA
7
21,461,413
21,529,068
RGD:1600115
ENSEMBL
G
Pnpt1
polyribonucleotide nucleotidyltransferase 1
ISO
14
110,130,417
110,161,762
RGD:1624291
RGD
G
Pnpt1
polyribonucleotide nucleotidyltransferase 1
IEA
14
110,130,417
110,161,762
RGD:1600115
ENSEMBL
G
Vash1
vasohibin 1
ISO
6
110,806,294
110,818,161
RGD:1624291
RGD
replicative cell aging
G
Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1
ISO
1
78,711,249
78,722,474
RGD:1624291
RGD
G
Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1
ISO
1
78,711,249
78,722,474
RGD:1624291
RGD
G
Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1
IEA
1
78,711,249
78,722,474
RGD:1600115
ENSEMBL
G
LOC100910944
reactive oxygen species modulator 1-like
IEA
RGD:1600115
ENSEMBL
G
Romo1
reactive oxygen species modulator 1
ISO
3
146,551,220
146,552,820
RGD:1624291
RGD
G
Romo1
reactive oxygen species modulator 1
IEA
3
146,551,220
146,552,820
RGD:1600115
ENSEMBL
G
Tmem115
transmembrane protein 115
IEP
8
112,781,304
112,786,168
RGD:2303064
RGD
G
Tp63
tumor protein p63
IMP
11
76,900,622
77,200,251
RGD:1600401
RGD
G
Wrn
Werner syndrome, RecQ helicase-like
ISO
16
62,535,144
62,668,700
RGD:1624291
RGD
replicative senescence
G
Atm
ataxia telangiectasia mutated
ISO
8
56,894,746
56,996,565
RGD:1624291
RGD
G
Atm
ataxia telangiectasia mutated
IEA
8
56,894,746
56,996,565
RGD:1600115
InterPro
G
Atr
ataxia telangiectasia and Rad3 related
ISO
8
100,936,342
101,014,881
RGD:1624291
RGD
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISO
5
108,908,749
108,916,380
RGD:1624291
RGD
G
Ctc1
CTS telomere maintenance complex component 1
ISO
10
55,768,182
55,788,836
RGD:1624291
RGD
G
Mme
membrane metallo-endopeptidase
ISO
2
153,031,724
153,114,515
RGD:1624291
RGD
G
Mme
membrane metallo-endopeptidase
ISS
2
153,031,724
153,114,515
RGD:1600115
UniProtKB
G
Pla2r1
phospholipase A2 receptor 1
ISO
3
42,121,966
42,250,869
RGD:1624291
RGD
G
Pla2r1
phospholipase A2 receptor 1
ISS
3
42,121,966
42,250,869
RGD:1600115
UniProtKB
G
Tert
telomerase reverse transcriptase
ISO
1
30,445,180
30,465,942
RGD:1624291
RGD
G
Tert
telomerase reverse transcriptase
IEA
1
30,445,180
30,465,942
RGD:1600115
ENSEMBL
G
Tp53
tumor protein p53
ISO
10
56,399,721
56,411,150
RGD:1624291
RGD
G
Wnt16
wingless-type MMTV integration site family, member 16
IEA
4
48,609,677
48,620,317
RGD:1600115
ENSEMBL
G
Wnt16
wingless-type MMTV integration site family, member 16
ISO
4
48,609,677
48,620,317
RGD:1624291
RGD
stress-induced premature senescence
G
Mapk14
mitogen activated protein kinase 14
ISO
20
6,939,249
7,000,378
RGD:1624291
RGD
G
Mapk14
mitogen activated protein kinase 14
IEA
20
6,939,249
7,000,378
RGD:1600115
ENSEMBL
G
Mapkapk5
mitogen-activated protein kinase-activated protein kinase 5
ISO
12
36,128,538
36,147,493
RGD:1624291
RGD
G
Mapkapk5
mitogen-activated protein kinase-activated protein kinase 5
IEA
12
36,128,538
36,147,493
RGD:1600115
ENSEMBL
G
Mapkapk5
mitogen-activated protein kinase-activated protein kinase 5
ISO
12
36,128,538
36,147,493
RGD:1624291
RGD
Term paths to the root one longest all shortest one shortest all one shortest and longest all longest