ONTOLOGY REPORT - ANNOTATIONS


Term:aging
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Accession:GO:0007568 term browser browse the term
Definition:A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700).
Synonyms:exact_synonym: ageing
 alt_id: GO:0016280
 xref_analog: Wikipedia:Aging


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aging term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ace angiotensin I converting enzyme GBrowse link IEP 10 95,361,338 95,381,455 RGD:6893473 RGD
G Ada adenosine deaminase GBrowse link IEP 3 154,636,530 154,660,637 RGD:1624293 RGD
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide GBrowse link IEP 2 235,952,313 235,970,671 RGD:5129089 RGD
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide GBrowse link IEP 2 235,979,108 235,991,515 RGD:5129089 RGD
G Adm adrenomedullin GBrowse link IEP 1 168,380,255 168,382,426 RGD:1625311 RGD
G Adm adrenomedullin GBrowse link IEP 1 168,380,255 168,382,426 RGD:2325638 RGD
G Adra1a adrenoceptor alpha 1A GBrowse link IDA 15 46,173,429 46,263,198 RGD:5688350 RGD
G Adra1a adrenoceptor alpha 1A GBrowse link IDA 15 46,173,429 46,263,198 RGD:1625777 RGD
G Adra1d adrenoceptor alpha 1D GBrowse link IDA 3 119,279,974 119,295,985 RGD:5688350 RGD
G Adrb1 adrenoceptor beta 1 GBrowse link IEP 1 263,025,655 263,027,055 RGD:5129117 RGD
G Adrb2 adrenoceptor beta 2, surface GBrowse link IEP 18 58,174,958 58,177,000 RGD:8548537 RGD
G Adrb3 adrenoceptor beta 3 GBrowse link IEP 16 69,163,620 69,166,384 RGD:2313169 RGD
G Adrbk1 adrenergic, beta, receptor kinase 1 GBrowse link IEP 1 206,873,002 206,892,868 RGD:1582266 RGD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link IEP 19 54,738,556 54,750,349 RGD:5129178 RGD
G Agtr1a angiotensin II receptor, type 1a GBrowse link IEP 17 40,629,318 40,684,982 RGD:5129178 RGD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link IDA 6 137,640,482 137,657,552 RGD:5509106 RGD
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 GBrowse link IEP 10 47,365,195 47,374,880 RGD:2300311 RGD
G Aldoc aldolase C, fructose-bisphosphate GBrowse link IDA 10 64,308,826 64,312,415 RGD:2301137 RGD
G Alox12 arachidonate 12-lipoxygenase GBrowse link IEP 10 57,080,603 57,092,874 RGD:2302179 RGD
G Amfr autocrine motility factor receptor, E3 ubiquitin protein ligase GBrowse link IEP 19 11,434,553 11,467,592 RGD:1643424 RGD
G Amh anti-Mullerian hormone GBrowse link IEP 7 10,417,325 10,419,673 RGD:2315641 RGD
G Aoc3 amine oxidase, copper containing 3 GBrowse link IEP 10 90,357,094 90,365,040 RGD:2313935 RGD
G Apaf1 apoptotic peptidase activating factor 1 GBrowse link IEP 7 27,932,908 28,020,533 RGD:2325740 RGD
G Apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 GBrowse link IDA 15 26,904,124 26,906,224 RGD:2315679 RGD
G Apod apolipoprotein D IEP RGD:2311181 RGD
G Apoe apolipoprotein E GBrowse link IDA 1 79,003,634 79,006,387 RGD:2317724 RGD
G Aqp2 aquaporin 2 (collecting duct) GBrowse link IEP 7 138,325,855 138,330,891 RGD:2313133 RGD
G Arg1 arginase 1 GBrowse link IEP 1 20,998,894 21,011,275 RGD:4143182 RGD
G Asl argininosuccinate lyase GBrowse link IEP 12 27,702,882 27,720,230 RGD:4140929 RGD
G Ass1 argininosuccinate synthase 1 GBrowse link IEP 3 10,578,717 10,622,332 RGD:4140929 RGD
G Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 GBrowse link IEP 7 36,493,661 36,600,280 RGD:2317748 RGD
G Atp5g3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) GBrowse link IEP 3 56,511,747 56,514,204 RGD:2301244 RGD
G Atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 GBrowse link IEP X 160,306,354 160,313,434 RGD:2301245 RGD
G Aurkb aurora kinase B GBrowse link IEP 10 55,798,710 55,804,367 RGD:2315123 RGD
G Bak1 BCL2-antagonist/killer 1 GBrowse link IEP 20 5,255,954 5,264,593 RGD:2316112 RGD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link IEP 13 12,730,736 12,905,108 RGD:2293079 RGD
G Bglap bone gamma-carboxyglutamate (gla) protein GBrowse link IEP 2 180,482,313 180,483,290 RGD:6483558 RGD
G C1qb complement component 1, q subcomponent, B chain GBrowse link IEP 5 155,647,524 155,653,074 RGD:1599511 RGD
G Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit GBrowse link IEP 16 5,383,259 5,703,361 RGD:6906923 RGD
G Cacybp calcyclin binding protein GBrowse link IEP 13 75,623,161 75,633,644 RGD:2326112 RGD
G Calca calcitonin-related polypeptide alpha GBrowse link IEP 1 172,686,168 172,691,061 RGD:2314033 RGD
G Canx calnexin GBrowse link IEP 10 35,850,944 35,883,494 RGD:2313153 RGD
G Capn10 calpain 10 IDA RGD:2317923 RGD
G Casp12 caspase 12 GBrowse link IEP 8 2,082,933 2,110,511 RGD:2311469 RGD
G Casp2 caspase 2 GBrowse link IEP 4 70,029,728 70,047,164 RGD:4107079 RGD
G Casp7 caspase 7 GBrowse link IEP 1 262,689,300 262,721,591 RGD:2311469 RGD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link IEP 5 160,704,234 160,721,796 RGD:2311469 RGD
G Cast calpastatin GBrowse link IEP 2 1,495,048 1,608,477 RGD:5509820 RGD
G Cat catalase GBrowse link IEP 3 88,654,077 88,686,212 RGD:5130205 RGD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link IEP 10 70,256,263 70,258,061 RGD:4891435 RGD
G Ccl5 chemokine (C-C motif) ligand 5 GBrowse link IEP 10 71,605,791 71,610,330 RGD:2307163 RGD
G Ccr5 chemokine (C-C motif) receptor 5 GBrowse link IEP 8 128,907,157 128,912,272 RGD:2307163 RGD
G Cd86 CD86 molecule GBrowse link IEP 11 66,215,233 66,238,882 RGD:2313439 RGD
G Cdkn1c cyclin-dependent kinase inhibitor 1C GBrowse link ISO 1 203,835,215 203,837,844 RGD:1624291 RGD
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link ISO 5 108,908,749 108,916,380 RGD:1624291 RGD
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link IEP 5 108,908,749 108,916,380 RGD:1358479 RGD
G Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) GBrowse link IEP 5 108,939,669 108,945,293 RGD:7248759 RGD
G Ciita class II, major histocompatibility complex, transactivator GBrowse link IEP 10 5,087,174 5,133,418 RGD:2313439 RGD
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase GBrowse link IEP 10 89,519,421 89,525,978 RGD:6483356 RGD
G Cnr1 cannabinoid receptor 1 (brain) GBrowse link IMP 5 50,427,173 50,445,471 RGD:2314647 RGD
G Col3a1 collagen, type III, alpha 1 GBrowse link IEP 9 44,281,582 44,317,831 RGD:7257557 RGD
G Cp ceruloplasmin (ferroxidase) GBrowse link IEP 2 105,086,278 105,135,367 RGD:1599628 RGD
G Crp C-reactive protein, pentraxin-related GBrowse link IEP 13 88,702,243 88,703,153 RGD:6482314 RGD
G Cryab crystallin, alpha B GBrowse link IEP 8 54,107,824 54,111,502 RGD:2303634 RGD
G Ctc1 CTS telomere maintenance complex component 1 GBrowse link ISO 10 55,768,182 55,788,836 RGD:1624291 RGD
G Ctnna1 catenin (cadherin-associated protein), alpha 1, 102kDa GBrowse link IEP 18 27,629,915 27,769,360 RGD:2289805 RGD
G Ctsc cathepsin C GBrowse link IEP 1 144,629,802 144,661,183 RGD:1599647 RGD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link IEP 8 61,462,207 61,468,237 RGD:5147748 RGD
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 IDA RGD:2307323 RGD
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 GBrowse link IEP 1 81,345,425 81,359,415 RGD:2301454 RGD
G Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 GBrowse link IEP 12 9,567,120 9,595,974 RGD:1625392 RGD
G Dcn decorin GBrowse link IEP 7 35,004,234 35,045,191 RGD:2311426 RGD
G Ddit3 DNA-damage inducible transcript 3 GBrowse link IEP 7 67,247,749 67,252,571 RGD:1299136 RGD
G Dld dihydrolipoamide dehydrogenase GBrowse link IEP 6 49,185,188 49,205,894 RGD:2306416 RGD
G Dmd dystrophin GBrowse link IEP X 71,501,362 71,671,414 RGD:6771366 RGD
G Ednra endothelin receptor type A GBrowse link IEP 19 32,042,366 32,108,153 RGD:4892581 RGD
G Ednrb endothelin receptor type B GBrowse link IEP 15 87,893,141 87,898,700 RGD:4892600 RGD
G Eif5a eukaryotic translation initiation factor 5A GBrowse link IEP 10 56,760,289 56,764,689 RGD:2308860 RGD
G Eno3 enolase 3, beta, muscle GBrowse link IEP 10 57,536,965 57,542,317 RGD:2301762 RGD
G Epo erythropoietin GBrowse link IEP 12 19,551,768 19,555,208 RGD:2313640 RGD
G Ercc2 excision repair cross-complementation group 2 IEA RGD:1600115 Ensembl
G Ercc2 excision repair cross-complementation group 2 ISO RGD:1624291 RGD
G Ercc2 excision repair cross-complementation group 2 ISO RGD:1624291 RGD
G Ercc2 excision repair cross-complementation group 2 ISO RGD:1624291 RGD
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link IEP 2 218,371,050 218,382,645 RGD:2313773 RGD
G Fads1 fatty acid desaturase 1 GBrowse link IEP 1 212,670,792 212,685,718 RGD:1625420 RGD
G Fas Fas cell surface death receptor GBrowse link IEP 1 238,259,443 238,274,745 RGD:1600330 RGD
G Fos FBJ osteosarcoma oncogene GBrowse link IEP 6 109,559,135 109,562,001 RGD:2293789 RGD
G Fosl2 fos-like antigen 2 IEP RGD:2293789 RGD
G Foxg1 forkhead box G1 GBrowse link IEP 6 69,217,672 69,220,482 RGD:2314183 RGD
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link IEP 1 136,209,969 136,222,057 RGD:1582625 RGD
G Gfra1 GDNF family receptor alpha 1 GBrowse link IEP 1 264,614,329 264,875,486 RGD:6480089 RGD
G Ggt1 gamma-glutamyltransferase 1 IEP RGD:2315578 RGD
G Gjb6 gap junction protein, beta 6 GBrowse link IEP 15 36,177,736 36,186,513 RGD:7364768 RGD
G Gnao1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O GBrowse link IDA 19 11,472,083 11,623,600 RGD:2302009 RGD
G Gpx1 glutathione peroxidase 1 IEP RGD:2306622 RGD
G Gpx4 glutathione peroxidase 4 GBrowse link IEP 7 11,162,521 11,165,318 RGD:2306622 RGD
G Grb2 growth factor receptor bound protein 2 GBrowse link IPI 10 105,722,014 105,818,649 RGD:1643178 RGD
G Gsn gelsolin GBrowse link IEP 3 14,360,245 14,386,313 RGD:1304020 RGD
G Gss glutathione synthetase GBrowse link IEP 3 146,057,517 146,087,820 RGD:2301454 RGD
G Gsta1 glutathione S-transferase alpha 1 GBrowse link IEP 9 20,051,501 20,068,146 RGD:2306661 RGD
G Gsta2 glutathione S-transferase alpha 2 GBrowse link IEP 8 83,299,249 83,312,958 RGD:2306661 RGD
G Gstm2 glutathione S-transferase mu 2 GBrowse link IEP 2 203,549,022 203,553,380 RGD:2302179 RGD
G Hcn2 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 GBrowse link IEP 7 11,485,257 11,503,614 RGD:2316624 RGD
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase GBrowse link IEP 2 27,127,504 27,149,580 RGD:2317945 RGD
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase GBrowse link IEP 2 27,127,504 27,149,580 RGD:5508699 RGD
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled GBrowse link IEP 15 55,463,743 55,532,293 RGD:1624378 RGD
G Ifi27l2b interferon, alpha-inducible protein 27 like 2B GBrowse link ISO 6 127,733,540 127,735,026 RGD:1624291 RGD
G Igfbp2 insulin-like growth factor binding protein 2 GBrowse link IEP 9 71,966,877 71,994,211 RGD:1626514 RGD
G Il10 interleukin 10 GBrowse link IEP 13 43,953,900 43,957,766 RGD:7364992 RGD
G Il15 interleukin 15 GBrowse link IEP 19 27,487,268 27,498,973 RGD:1626613 RGD
G Il1b interleukin 1 beta GBrowse link IMP 3 116,964,422 116,970,867 RGD:1626647 RGD
G Il6 interleukin 6 GBrowse link IEP 4 456,799 461,376 RGD:2306935 RGD
G Irak1 interleukin-1 receptor-associated kinase 1 GBrowse link IEP X 159,960,184 159,969,180 RGD:7495793 RGD
G Ireb2 iron responsive element binding protein 2 GBrowse link IEP 8 58,433,218 58,477,305 RGD:6893272 RGD
G Itgb2 integrin, beta 2 GBrowse link IEP 20 11,446,521 11,485,009 RGD:6482194 RGD
G Jun jun proto-oncogene GBrowse link IEP 5 115,358,166 115,361,259 RGD:2293789 RGD
G Jund jun D proto-oncogene GBrowse link IEP 16 19,239,694 19,241,529 RGD:2293789 RGD
G Kcne2 potassium voltage-gated channel, Isk-related family, member 2 GBrowse link IEP 11 32,277,711 32,290,828 RGD:7243962 RGD
G Kdr kinase insert domain receptor IEP RGD:8549775 RGD
G Kl Klotho GBrowse link TAS 12 3,732,712 3,772,371 RGD:633145 RGD
G Kl Klotho GBrowse link ISO 12 3,732,712 3,772,371 RGD:1624291 RGD
G Kl Klotho GBrowse link ISO 12 3,732,712 3,772,371 RGD:1624291 RGD
G Lck lymphocyte-specific protein tyrosine kinase GBrowse link IEP 5 148,707,505 148,718,296 RGD:1600226 RGD
G Ldlr low density lipoprotein receptor GBrowse link IEP 8 20,824,040 20,846,920 RGD:1581819 RGD
G Litaf lipopolysaccharide-induced TNF factor GBrowse link IEP 10 4,614,177 4,623,903 RGD:7247626 RGD
G LOC691889 similar to ATPase, aminophospholipid transporter-like, class I, type 8A, member 2 GBrowse link ISO 15 38,759,902 39,271,237 RGD:1624291 RGD
G LOC691889 similar to ATPase, aminophospholipid transporter-like, class I, type 8A, member 2 GBrowse link IEA 15 38,759,902 39,271,237 RGD:1600115 Ensembl
G Lonp1 lon peptidase 1, mitochondrial IEP RGD:2303495 RGD
G Lrp1 low density lipoprotein receptor-related protein 1 GBrowse link IEP 7 67,520,575 67,601,549 RGD:1625018 RGD
G Lrp2 low density lipoprotein receptor-related protein 2 GBrowse link IEP 3 51,563,764 51,724,478 RGD:1641828 RGD
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 GBrowse link IEP 7 11,553,219 11,556,621 RGD:2311548 RGD
G Mbp myelin basic protein GBrowse link IEP 18 78,943,608 79,057,329 RGD:7327192 RGD
G Mgea5 meningioma expressed antigen 5 (hyaluronidase) GBrowse link IEP 1 250,966,386 251,000,363 RGD:2305952 RGD
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link IEP 20 13,191,986 13,192,851 RGD:1641992 RGD
G Mmp2 matrix metallopeptidase 2 GBrowse link IEP 19 15,246,036 15,275,061 RGD:2290430 RGD
G Mmp9 matrix metallopeptidase 9 GBrowse link IEP 3 155,985,473 155,993,433 RGD:2290430 RGD
G Mpo myeloperoxidase GBrowse link IEP 10 76,085,872 76,097,012 RGD:2317972 RGD
G Msra methionine sulfoxide reductase A GBrowse link IEP 15 43,509,775 43,756,283 RGD:70794 RGD
G Msra methionine sulfoxide reductase A GBrowse link IDA 15 43,509,775 43,756,283 RGD:2324653 RGD
G Mt-atp6 mitochondrially encoded ATP synthase 6 GBrowse link IEP MT 7,919 8,599 RGD:5490295 RGD
G Mt-co1 mitochondrially encoded cytochrome c oxidase I GBrowse link IEP MT 5,323 6,867 RGD:2302303 RGD
G Mt-nd4 mitochondrially encoded NADH dehydrogenase 4 GBrowse link IDA MT 10,160 11,537 RGD:2302306 RGD
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) GBrowse link IEP 16 23,855,555 23,876,531 RGD:5131598 RGD
G Ncam1 neural cell adhesion molecule 1 GBrowse link IDA 8 52,822,350 53,120,572 RGD:2326009 RGD
G Ncf2 neutrophil cytosolic factor 2 GBrowse link IEP 13 67,806,516 67,834,105 RGD:2292095 RGD
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 GBrowse link IEP 1 251,521,559 251,527,815 RGD:2302396 RGD
G Ngf nerve growth factor (beta polypeptide) GBrowse link IEP 2 197,621,726 197,632,960 RGD:5144122 RGD
G Nos1 nitric oxide synthase 1, neuronal GBrowse link IEP 12 39,812,500 39,869,484 RGD:1642135 RGD
G Nos2 nitric oxide synthase 2, inducible GBrowse link IEP 10 65,036,884 65,072,453 RGD:2313213 RGD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link IEP 4 6,158,847 6,179,441 RGD:2292095 RGD
G Nox4 NADPH oxidase 4 GBrowse link IEP 1 143,415,816 143,603,554 RGD:2324660 RGD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link IEP 19 37,251,147 37,266,040 RGD:5133233 RGD
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 GBrowse link IEP 18 32,371,496 32,459,145 RGD:4892124 RGD
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 GBrowse link IEP 2 179,838,740 179,855,545 RGD:5684347 RGD
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 GBrowse link IEP 2 179,838,740 179,855,545 RGD:5144122 RGD
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 GBrowse link IEP 17 11,494,463 11,811,654 RGD:5684924 RGD
G Opa1 optic atrophy 1 GBrowse link IEP 11 73,005,470 73,058,136 RGD:7829729 RGD
G P2ry1 purinergic receptor P2Y, G-protein coupled, 1 GBrowse link IEP 2 150,460,361 150,465,855 RGD:2316735 RGD
G P2ry2 purinergic receptor P2Y, G-protein coupled, 2 GBrowse link IEP 1 158,440,018 158,454,213 RGD:2316735 RGD
G Pax2 paired box 2 GBrowse link IEP 1 249,804,055 249,895,306 RGD:2316745 RGD
G Pde4d phosphodiesterase 4D, cAMP-specific GBrowse link ISO 2 40,196,097 41,311,012 RGD:1624291 RGD
G Pebp1 phosphatidylethanolamine binding protein 1 GBrowse link IEP 12 40,491,393 40,495,593 RGD:2302808 RGD
G Phox2a paired-like homeobox 2a GBrowse link IEP 1 159,273,524 159,312,136 RGD:1579826 RGD
G Pik3r1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) GBrowse link IEP 2 32,602,673 32,675,350 RGD:1625220 RGD
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) GBrowse link IEP 13 64,135,729 64,280,815 RGD:1642464 RGD
G Polg polymerase (DNA directed), gamma GBrowse link ISO 1 135,197,075 135,212,178 RGD:1624291 RGD
G Polg polymerase (DNA directed), gamma GBrowse link IEA 1 135,197,075 135,212,178 RGD:1600115 Ensembl
G Prkca protein kinase C, alpha GBrowse link IEP 10 97,367,196 97,638,910 RGD:2298670 RGD
G Prkcd protein kinase C, delta GBrowse link IEP 16 5,954,218 5,975,743 RGD:1642546 RGD
G Prkcq protein kinase C, theta GBrowse link IEP 17 78,486,998 78,566,741 RGD:1625620 RGD
G Pten phosphatase and tensin homolog GBrowse link IEP 1 236,771,027 236,837,261 RGD:2292534 RGD
G Ptgs1 prostaglandin-endoperoxide synthase 1 GBrowse link IEP 3 15,343,832 15,365,412 RGD:2300265 RGD
G Pth1r parathyroid hormone 1 receptor GBrowse link IEP 8 115,099,763 115,119,362 RGD:1599981 RGD
G Rela v-rel avian reticuloendotheliosis viral oncogene homolog A GBrowse link IEP 1 208,262,669 208,273,148 RGD:2298786 RGD
G Retn resistin GBrowse link IEP 12 2,499,630 2,501,370 RGD:7207255 RGD
G Rnpep arginyl aminopeptidase (aminopeptidase B) GBrowse link IEP 13 48,267,923 48,286,295 RGD:2325947 RGD
G Rpn2 ribophorin II GBrowse link IEP 3 147,976,544 148,023,743 RGD:2325966 RGD
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 GBrowse link IEP 10 76,657,024 76,698,088 RGD:1643019 RGD
G Rtn4 reticulon 4 GBrowse link IEP 14 110,725,089 110,772,578 RGD:2314960 RGD
G Rxra retinoid X receptor alpha GBrowse link IEP 3 6,605,782 6,689,224 RGD:1643118 RGD
G Scap SREBF chaperone GBrowse link IEP 8 114,706,479 114,761,342 RGD:1581819 RGD
G Serpina7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 GBrowse link IEP X 126,739,203 126,744,763 RGD:1600136 RGD
G Serpinf1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 GBrowse link IEP 10 62,713,441 62,739,444 RGD:2312350 RGD
G Shc1 SHC (Src homology 2 domain containing) transforming protein 1 GBrowse link IPI 2 181,616,581 181,628,144 RGD:1643178 RGD
G Si sucrase-isomaltase (alpha-glucosidase) GBrowse link IEP 2 163,520,975 163,601,280 RGD:1625553 RGD
G Sin3a SIN3 transcription regulator family member A GBrowse link IDA 8 60,832,595 60,884,764 RGD:2306468 RGD
G Sirt3 sirtuin 3 GBrowse link IEP 1 201,021,391 201,043,756 RGD:8158103 RGD
G Slc18a2 solute carrier family 18 (vesicular monoamine transporter), member 2 GBrowse link IDA 1 265,789,917 265,824,551 RGD:2317339 RGD
G Slc32a1 solute carrier family 32 (GABA vesicular transporter), member 1 GBrowse link IEP 3 149,342,399 149,347,124 RGD:2324692 RGD
G Slc34a2 solute carrier family 34 (type II sodium/phosphate contransporter), member 2 GBrowse link IEP 14 62,660,006 62,679,311 RGD:2311313 RGD
G Slc6a3 solute carrier family 6 (neurotransmitter transporter), member 3 GBrowse link IEP 1 30,516,568 30,557,540 RGD:1625669 RGD
G Snca synuclein, alpha (non A4 component of amyloid precursor) GBrowse link IEP 4 89,613,731 89,722,807 RGD:6218973 RGD
G Socs2 suppressor of cytokine signaling 2 GBrowse link IEP 7 32,605,714 32,608,323 RGD:2298927 RGD
G Socs3 suppressor of cytokine signaling 3 GBrowse link IEP 10 107,958,468 107,959,330 RGD:625538 RGD
G Sod1 superoxide dismutase 1, soluble GBrowse link ISO 11 29,810,766 29,816,342 RGD:1624291 RGD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link IEP 1 41,862,997 41,870,327 RGD:1625691 RGD
G Srebf1 sterol regulatory element binding transcription factor 1 GBrowse link IEP 10 46,461,684 46,483,646 RGD:1581819 RGD
G Srebf2 sterol regulatory element binding transcription factor 2 GBrowse link IEP 7 120,522,511 120,580,212 RGD:1581819 RGD
G Srr serine racemase GBrowse link IEP 10 62,217,481 62,234,831 RGD:2302214 RGD
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 GBrowse link IEP 1 75,632,632 75,708,022 RGD:2317008 RGD
G Tacr3 tachykinin receptor 3 GBrowse link IEP 2 232,309,015 232,404,964 RGD:2305954 RGD
G Tfrc transferrin receptor GBrowse link IEP 11 69,976,258 69,998,098 RGD:2292027 RGD
G Tgfb1 transforming growth factor, beta 1 GBrowse link IEP 1 80,894,705 80,911,020 RGD:2302033 RGD
G Tgfb2 transforming growth factor, beta 2 GBrowse link IEP 13 102,718,703 102,818,768 RGD:2302033 RGD
G Tgfb3 transforming growth factor, beta 3 GBrowse link IEP 6 110,173,443 110,195,215 RGD:2302033 RGD
G Tgfbr1 transforming growth factor, beta receptor 1 GBrowse link IEP 5 63,976,868 64,034,058 RGD:2302033 RGD
G Tgfbr2 transforming growth factor, beta receptor 2 GBrowse link IEP 8 120,593,595 120,680,453 RGD:2302033 RGD
G Timp1 TIMP metallopeptidase inhibitor 1 GBrowse link IEP X 12,542,496 12,547,094 RGD:2290357 RGD
G Timp2 TIMP metallopeptidase inhibitor 2 GBrowse link IEP 10 108,310,473 108,358,821 RGD:2290357 RGD
G Timp2 TIMP metallopeptidase inhibitor 2 GBrowse link IEP 10 108,310,473 108,358,821 RGD:2290430 RGD
G Timp3 TIMP metallopeptidase inhibitor 3 GBrowse link IEP 7 19,677,144 19,727,072 RGD:2290357 RGD
G Timp3 TIMP metallopeptidase inhibitor 3 GBrowse link IEP 7 19,677,144 19,727,072 RGD:2290430 RGD
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b GBrowse link IEP 5 163,666,541 163,697,484 RGD:7245943 RGD
G Top2a topoisomerase (DNA) II alpha GBrowse link IEP 10 87,771,337 87,800,960 RGD:2315123 RGD
G Tp53 tumor protein p53 GBrowse link IEP 10 56,399,721 56,411,150 RGD:2290558 RGD
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 GBrowse link IEP 8 5,472,515 5,577,537 RGD:7247586 RGD
G Tspo translocator protein GBrowse link IEP 7 121,597,084 121,599,342 RGD:2317163 RGD
G Tyms thymidylate synthetase GBrowse link IEP 9 112,604,912 112,617,706 RGD:2317423 RGD
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) GBrowse link IEP 1 157,925,514 157,928,222 RGD:7204432 RGD
G Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) GBrowse link IEP 1 157,896,001 157,909,608 RGD:2313527 RGD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link IEP 2 212,277,654 212,297,376 RGD:2313112 RGD
G Vdr vitamin D (1,25- dihydroxyvitamin D3) receptor GBrowse link IEP 7 136,567,614 136,617,280 RGD:4889988 RGD
G Vegfa vascular endothelial growth factor A GBrowse link IEP 9 10,520,730 10,536,071 RGD:8549775 RGD
G Vim vimentin GBrowse link IEP 17 87,847,280 87,855,763 RGD:6480444 RGD
age-dependent response to oxidative stress term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cln8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) GBrowse link ISO 16 79,569,745 79,579,636 RGD:1624291 RGD
G Cln8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) GBrowse link IEA 16 79,569,745 79,579,636 RGD:1600115 Ensembl
G Coq7 coenzyme Q7 homolog, ubiquinone (yeast) GBrowse link ISO 1 176,722,271 176,746,436 RGD:1624291 RGD
G Coq7 coenzyme Q7 homolog, ubiquinone (yeast) GBrowse link IEA 1 176,722,271 176,746,436 RGD:1600115 Ensembl
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link ISO 1 41,862,997 41,870,327 RGD:1624291 RGD
age-dependent response to reactive oxygen species term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link ISO 1 41,862,997 41,870,327 RGD:1624291 RGD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link ISS 1 41,862,997 41,870,327 RGD:1600115 UniProt
age-dependent telomere shortening term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Terf1 telomeric repeat binding factor (NIMA-interacting) 1 GBrowse link ISO 5 2,556,918 2,586,086 RGD:1624291 RGD
G Terf1 telomeric repeat binding factor (NIMA-interacting) 1 GBrowse link IEA 5 2,556,918 2,586,086 RGD:1600115 Ensembl
cell aging term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link ISO 13 12,730,736 12,905,108 RGD:1624291 RGD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link IEA 13 12,730,736 12,905,108 RGD:1600115 Ensembl
G Bglap bone gamma-carboxyglutamate (gla) protein GBrowse link IEP 2 180,482,313 180,483,290 RGD:2316145 RGD
G Brca2 breast cancer 2, early onset GBrowse link ISO 12 4,282,952 4,323,693 RGD:1624291 RGD
G Brca2 breast cancer 2, early onset GBrowse link IEA 12 4,282,952 4,323,693 RGD:1600115 Ensembl
G Cdk1 cyclin-dependent kinase 1 GBrowse link IDA 20 20,018,044 20,044,030 RGD:2301352 RGD
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link ISO 5 108,908,749 108,916,380 RGD:1624291 RGD
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 GBrowse link IEP 1 12,721,500 12,723,943 RGD:5147849 RGD
G Dnaja3 DnaJ (Hsp40) homolog, subfamily A, member 3 GBrowse link ISO 10 10,984,721 11,009,374 RGD:1624291 RGD
G Dnaja3 DnaJ (Hsp40) homolog, subfamily A, member 3 GBrowse link IEA 10 10,984,721 11,009,374 RGD:1600115 Ensembl
G Hras Harvey rat sarcoma virus oncogene GBrowse link ISO 1 201,385,705 201,388,987 RGD:1624291 RGD
G Hras Harvey rat sarcoma virus oncogene GBrowse link ISO 1 201,385,705 201,388,987 RGD:1624291 RGD
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 GBrowse link IEP X 41,489,343 41,491,788 RGD:2302236 RGD
G Htt huntingtin GBrowse link ISO 14 81,490,322 81,636,856 RGD:1624291 RGD
G Htt huntingtin GBrowse link IEA 14 81,490,322 81,636,856 RGD:1600115 Ensembl
G Icam1 intercellular adhesion molecule 1 GBrowse link IEP 8 20,040,177 20,051,939 RGD:4145420 RGD
G Ilk integrin-linked kinase GBrowse link IMP 1 163,481,299 163,487,550 RGD:2301768 RGD
G Met met proto-oncogene GBrowse link IEP 4 43,134,183 43,211,355 RGD:2317463 RGD
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link ISO 20 13,191,986 13,192,851 RGD:1624291 RGD
G Mnt MAX network transcriptional repressor GBrowse link ISO 10 62,146,582 62,161,832 RGD:1624291 RGD
G Mnt MAX network transcriptional repressor GBrowse link IEA 10 62,146,582 62,161,832 RGD:1600115 Ensembl
G Morc3 MORC family CW-type zinc finger 3 GBrowse link IEA 11 34,061,754 34,104,508 RGD:1600115 Ensembl
G Morc3 MORC family CW-type zinc finger 3 GBrowse link ISO 11 34,061,754 34,104,508 RGD:1624291 RGD
G Nox4 NADPH oxidase 4 GBrowse link ISO 1 143,415,816 143,603,554 RGD:1624291 RGD
G Nox4 NADPH oxidase 4 GBrowse link ISS 1 143,415,816 143,603,554 RGD:1600115 UniProt
G Npm1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) GBrowse link ISO 10 18,051,990 18,062,714 RGD:1624291 RGD
G Npm1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) GBrowse link ISS 10 18,051,990 18,062,714 RGD:1600115 UniProt
G Nup62 nucleoporin 62 GBrowse link ISO 1 95,288,019 95,303,545 RGD:1624291 RGD
G Nup62 nucleoporin 62 GBrowse link IEA 1 95,288,019 95,303,545 RGD:1600115 Ensembl
G Pdcd4 programmed cell death 4 GBrowse link ISO 1 260,183,648 260,202,032 RGD:1624291 RGD
G Pdcd4 programmed cell death 4 GBrowse link ISS 1 260,183,648 260,202,032 RGD:1600115 UniProt
G Pml promyelocytic leukemia GBrowse link ISO 8 62,020,438 62,051,927 RGD:1624291 RGD
G Pot1b protection of telomeres 1B IEA RGD:1600115 Ensembl
G Prelp proline/arginine-rich end leucine-rich repeat protein GBrowse link ISO 13 46,863,392 46,874,172 RGD:1624291 RGD
G Prelp proline/arginine-rich end leucine-rich repeat protein GBrowse link IEA 13 46,863,392 46,874,172 RGD:1600115 Ensembl
G Sod1 superoxide dismutase 1, soluble GBrowse link ISO 11 29,810,766 29,816,342 RGD:1624291 RGD
G Sod1 superoxide dismutase 1, soluble GBrowse link ISS 11 29,810,766 29,816,342 RGD:1600115 UniProt
G Tbx2 T-box 2 GBrowse link ISO 10 74,085,203 74,092,988 RGD:1624291 RGD
G Tbx2 T-box 2 GBrowse link ISO 10 74,085,203 74,092,988 RGD:1624291 RGD
G Tbx3 T-box 3 GBrowse link ISO 12 38,155,494 38,166,670 RGD:1624291 RGD
G Tbx3 T-box 3 GBrowse link ISO 12 38,155,494 38,166,670 RGD:1624291 RGD
G Tbx3 T-box 3 GBrowse link ISO 12 38,155,494 38,166,670 RGD:1624291 RGD
G Tbx3 T-box 3 GBrowse link ISS 12 38,155,494 38,166,670 RGD:1600115 UniProt
G Tp53 tumor protein p53 GBrowse link ISO 10 56,399,721 56,411,150 RGD:1624291 RGD
G Tp53 tumor protein p53 GBrowse link ISO 10 56,399,721 56,411,150 RGD:1624291 RGD
G Tp53 tumor protein p53 GBrowse link ISS 10 56,399,721 56,411,150 RGD:1600115 UniProt
G Tp63 tumor protein p63 GBrowse link ISO 11 76,900,622 77,200,251 RGD:1624291 RGD
G Wrn Werner syndrome, RecQ helicase-like GBrowse link ISO 16 62,535,144 62,668,700 RGD:1624291 RGD
G Zmiz1 zinc finger, MIZ-type containing 1 GBrowse link ISO 16 1,037,882 1,245,259 RGD:1624291 RGD
G Zmiz1 zinc finger, MIZ-type containing 1 GBrowse link IEA 16 1,037,882 1,245,259 RGD:1600115 Ensembl
cellular senescence term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Calr calreticulin GBrowse link ISO 19 24,964,775 24,969,670 RGD:1624291 RGD
G Calr calreticulin GBrowse link ISO 19 24,964,775 24,969,670 RGD:1624291 RGD
G Calr calreticulin GBrowse link IEA 19 24,964,775 24,969,670 RGD:1600115 Ensembl
G Calr calreticulin GBrowse link IEA 19 24,964,775 24,969,670 RGD:1600115 Ensembl
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link ISO 20 7,376,325 7,386,778 RGD:1624291 RGD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link IEA 20 7,376,325 7,386,778 RGD:1600115 Ensembl
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link ISO 5 108,908,749 108,916,380 RGD:1624291 RGD
G Hras Harvey rat sarcoma virus oncogene GBrowse link ISO 1 201,385,705 201,388,987 RGD:1624291 RGD
G Hras Harvey rat sarcoma virus oncogene GBrowse link IEA 1 201,385,705 201,388,987 RGD:1600115 Ensembl
G Id2 inhibitor of DNA binding 2 GBrowse link ISO 6 42,781,476 42,783,307 RGD:1624291 RGD
G Id2 inhibitor of DNA binding 2 GBrowse link ISS 6 42,781,476 42,783,307 RGD:1600115 UniProt
G Kat6a K(lysine) acetyltransferase 6A GBrowse link ISS 16 73,553,868 73,634,794 RGD:1600115 UniProt
G Kat6a K(lysine) acetyltransferase 6A GBrowse link ISO 16 73,553,868 73,634,794 RGD:1624291 RGD
G Map2k1 mitogen activated protein kinase kinase 1 GBrowse link ISO 8 68,379,074 68,451,554 RGD:1624291 RGD
G Map2k1 mitogen activated protein kinase kinase 1 GBrowse link IEA 8 68,379,074 68,451,554 RGD:1600115 Ensembl
G Nsmce2 non-SMC element 2, MMS21 homolog (S. cerevisiae) GBrowse link ISO 7 96,167,635 96,393,594 RGD:1624291 RGD
G Nsmce2 non-SMC element 2, MMS21 homolog (S. cerevisiae) GBrowse link ISS 7 96,167,635 96,393,594 RGD:1600115 UniProt
G Opa1 optic atrophy 1 GBrowse link ISO 11 73,005,470 73,058,136 RGD:1624291 RGD
G Opa1 optic atrophy 1 GBrowse link IEA 11 73,005,470 73,058,136 RGD:1600115 Ensembl
G Pml promyelocytic leukemia GBrowse link ISO 8 62,020,438 62,051,927 RGD:1624291 RGD
G Pml promyelocytic leukemia GBrowse link ISO 8 62,020,438 62,051,927 RGD:1624291 RGD
G Pml promyelocytic leukemia GBrowse link ISO 8 62,020,438 62,051,927 RGD:1624291 RGD
G Pml promyelocytic leukemia GBrowse link IEA 8 62,020,438 62,051,927 RGD:1600115 Ensembl
G Prkcd protein kinase C, delta GBrowse link ISO 16 5,954,218 5,975,743 RGD:1624291 RGD
G RGD1305645 similar to RIKEN cDNA 1500015O10 GBrowse link ISO 9 42,931,051 42,950,605 RGD:1624291 RGD
G RGD1305645 similar to RIKEN cDNA 1500015O10 GBrowse link IEA 9 42,931,051 42,950,605 RGD:1600115 Ensembl
G Smc5 structural maintenance of chromosomes 5 GBrowse link IEA 1 226,494,137 226,566,143 RGD:1600115 Ensembl
G Smc5 structural maintenance of chromosomes 5 GBrowse link ISO 1 226,494,137 226,566,143 RGD:1624291 RGD
G Smc6 structural maintenance of chromosomes 6 GBrowse link IEA 6 34,710,177 34,763,158 RGD:1600115 Ensembl
G Smc6 structural maintenance of chromosomes 6 GBrowse link ISO 6 34,710,177 34,763,158 RGD:1624291 RGD
G Srf serum response factor (c-fos serum response element-binding transcription factor) GBrowse link ISO 9 9,788,378 9,797,639 RGD:1624291 RGD
G Srf serum response factor (c-fos serum response element-binding transcription factor) GBrowse link IEA 9 9,788,378 9,797,639 RGD:1600115 Ensembl
G Tbx2 T-box 2 GBrowse link ISO 10 74,085,203 74,092,988 RGD:1624291 RGD
G Tbx2 T-box 2 GBrowse link IEA 10 74,085,203 74,092,988 RGD:1600115 Ensembl
G Tbx3 T-box 3 GBrowse link ISS 12 38,155,494 38,166,670 RGD:1600115 UniProt
G Tbx3 T-box 3 GBrowse link ISO 12 38,155,494 38,166,670 RGD:1624291 RGD
chronological cell aging term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Eng endoglin ISO RGD:1624291 RGD
G Eng endoglin IEA RGD:1600115 Ensembl
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link ISO 12 20,931,996 20,942,374 RGD:1624291 RGD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link IEA 12 20,931,996 20,942,374 RGD:1600115 Ensembl
determination of adult lifespan term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Bbc3 Bcl-2 binding component 3 IEA RGD:1600115 Ensembl
G Coq7 coenzyme Q7 homolog, ubiquinone (yeast) GBrowse link ISO 1 176,722,271 176,746,436 RGD:1624291 RGD
G Coq7 coenzyme Q7 homolog, ubiquinone (yeast) GBrowse link IEA 1 176,722,271 176,746,436 RGD:1600115 Ensembl
G Ercc5 excision repair cross-complementation group 5 GBrowse link ISO 9 43,248,023 43,293,196 RGD:1624291 RGD
G Ercc5 excision repair cross-complementation group 5 GBrowse link IEA 9 43,248,023 43,293,196 RGD:1600115 Ensembl
G Ghrhr growth hormone releasing hormone receptor GBrowse link ISO 4 84,135,530 84,148,503 RGD:1624291 RGD
G Ghrhr growth hormone releasing hormone receptor GBrowse link IEA 4 84,135,530 84,148,503 RGD:1600115 Ensembl
G Htt huntingtin GBrowse link ISO 14 81,490,322 81,636,856 RGD:1624291 RGD
G Htt huntingtin GBrowse link ISO 14 81,490,322 81,636,856 RGD:1624291 RGD
G Htt huntingtin GBrowse link IEA 14 81,490,322 81,636,856 RGD:1600115 Ensembl
G Ide insulin degrading enzyme GBrowse link ISO 1 241,547,869 241,646,052 RGD:1624291 RGD
G Ide insulin degrading enzyme GBrowse link IEA 1 241,547,869 241,646,052 RGD:1600115 Ensembl
G Inpp5d inositol polyphosphate-5-phosphatase D GBrowse link ISO 9 86,576,742 86,682,240 RGD:1624291 RGD
G Inpp5d inositol polyphosphate-5-phosphatase D GBrowse link IEA 9 86,576,742 86,682,240 RGD:1600115 Ensembl
G Lrrk2 leucine-rich repeat kinase 2 GBrowse link ISO 7 130,105,902 130,267,747 RGD:1624291 RGD
G Lrrk2 leucine-rich repeat kinase 2 GBrowse link IEA 7 130,105,902 130,267,747 RGD:1600115 Ensembl
G Msh2 mutS homolog 2 GBrowse link IEA 6 11,199,906 11,258,350 RGD:1600115 Ensembl
G Msh2 mutS homolog 2 GBrowse link ISO 6 11,199,906 11,258,350 RGD:1624291 RGD
G Msh6 mutS homolog 6 GBrowse link ISO 6 11,525,292 11,542,592 RGD:1624291 RGD
G Msh6 mutS homolog 6 GBrowse link ISO 6 11,525,292 11,542,592 RGD:1624291 RGD
G Msh6 mutS homolog 6 GBrowse link IEA 6 11,525,292 11,542,592 RGD:1600115 Ensembl
G Pou1f1 POU class 1 homeobox 1 GBrowse link ISO 11 2,959,383 2,980,545 RGD:1624291 RGD
G Pou1f1 POU class 1 homeobox 1 GBrowse link IEA 11 2,959,383 2,980,545 RGD:1600115 Ensembl
G Tfcp2l1 transcription factor CP2-like 1 GBrowse link IEA 13 31,288,228 31,401,482 RGD:1600115 Ensembl
G Tfcp2l1 transcription factor CP2-like 1 GBrowse link ISO 13 31,288,228 31,401,482 RGD:1624291 RGD
G Tp53 tumor protein p53 GBrowse link ISO 10 56,399,721 56,411,150 RGD:1624291 RGD
menopause term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cat catalase GBrowse link IEP 3 88,654,077 88,686,212 RGD:5130890 RGD
multicellular organismal aging term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Acan aggrecan GBrowse link IEP 1 134,787,341 134,848,992 RGD:2315752 RGD
G Adrbk2 adrenergic, beta, receptor kinase 2 IEP RGD:5685607 RGD
G Cisd2 CDGSH iron sulfur domain 2 GBrowse link ISO 2 232,902,533 232,927,338 RGD:1624291 RGD
G Cisd2 CDGSH iron sulfur domain 2 GBrowse link IEA 2 232,902,533 232,927,338 RGD:1600115 Ensembl
G Ctsl cathepsin L GBrowse link IEP 17 6,288,013 6,294,174 RGD:2315581 RGD
G Dbh dopamine beta-hydroxylase (dopamine beta-monooxygenase) GBrowse link IEP 3 6,052,706 6,069,826 RGD:5129682 RGD
G Ddc dopa decarboxylase (aromatic L-amino acid decarboxylase) GBrowse link IEP 14 92,698,636 92,788,635 RGD:5129108 RGD
G Edn1 endothelin 1 GBrowse link IEP 17 28,303,886 28,309,775 RGD:4144863 RGD
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 GBrowse link ISO 1 78,711,249 78,722,474 RGD:1624291 RGD
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 GBrowse link IEA 1 78,711,249 78,722,474 RGD:1600115 Ensembl
G Helt helt bHLH transcription factor GBrowse link IEA 16 49,271,310 49,273,233 RGD:1600115 Ensembl
G Helt helt bHLH transcription factor GBrowse link ISO 16 49,271,310 49,273,233 RGD:1624291 RGD
G Hyal2 hyaluronoglucosaminidase 2 GBrowse link IEA 8 112,817,001 112,820,693 RGD:1600115 Ensembl
G Hyal2 hyaluronoglucosaminidase 2 GBrowse link ISO 8 112,817,001 112,820,693 RGD:1624291 RGD
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 GBrowse link ISO 3 18,498,913 18,519,738 RGD:1624291 RGD
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 GBrowse link IEA 3 18,498,913 18,519,738 RGD:1600115 Ensembl
G Rnf165 ring finger protein 165 GBrowse link ISO 18 74,413,654 74,530,319 RGD:1624291 RGD
G Sec63 SEC63 homolog (S. cerevisiae) GBrowse link IEA 20 46,669,125 46,738,077 RGD:1600115 Ensembl
G Sec63 SEC63 homolog (S. cerevisiae) GBrowse link ISO 20 46,669,125 46,738,077 RGD:1624291 RGD
G Serp1 stress-associated endoplasmic reticulum protein 1 GBrowse link ISO 2 147,866,072 147,870,096 RGD:1624291 RGD
G Serp1 stress-associated endoplasmic reticulum protein 1 GBrowse link IEA 2 147,866,072 147,870,096 RGD:1600115 Ensembl
G Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 GBrowse link ISO 3 87,870,558 87,992,401 RGD:1624291 RGD
G Spef2 sperm flagellar 2 GBrowse link ISO 2 59,163,063 59,333,207 RGD:1624291 RGD
G Th tyrosine hydroxylase GBrowse link IEP 1 203,164,253 203,171,506 RGD:5129108 RGD
G Tp63 tumor protein p63 GBrowse link ISO 11 76,900,622 77,200,251 RGD:1624291 RGD
G Wrn Werner syndrome, RecQ helicase-like GBrowse link ISO 16 62,535,144 62,668,700 RGD:1624291 RGD
G Wrn Werner syndrome, RecQ helicase-like GBrowse link ISO 16 62,535,144 62,668,700 RGD:1624291 RGD
G Wrn Werner syndrome, RecQ helicase-like GBrowse link IEA 16 62,535,144 62,668,700 RGD:1600115 Ensembl
G Wrn Werner syndrome, RecQ helicase-like GBrowse link IEA 16 62,535,144 62,668,700 RGD:1600115 Ensembl
negative regulation of cell aging term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Foxm1 forkhead box M1 GBrowse link ISO 4 165,383,666 165,394,688 RGD:1624291 RGD
G Foxm1 forkhead box M1 GBrowse link IEA 4 165,383,666 165,394,688 RGD:1600115 Ensembl
G Fzr1 fizzy/cell division cycle 20 related 1 (Drosophila) GBrowse link IEA 7 9,816,491 9,829,006 RGD:1600115 Ensembl
G Fzr1 fizzy/cell division cycle 20 related 1 (Drosophila) GBrowse link ISO 7 9,816,491 9,829,006 RGD:1624291 RGD
G March5 membrane-associated ring finger (C3HC4) 5 GBrowse link IEA 1 241,475,394 241,495,500 RGD:1600115 Ensembl
G March5 membrane-associated ring finger (C3HC4) 5 GBrowse link ISO 1 241,475,394 241,495,500 RGD:1624291 RGD
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link ISO 20 13,191,986 13,192,851 RGD:1624291 RGD
G Pten phosphatase and tensin homolog GBrowse link ISO 1 236,771,027 236,837,261 RGD:1624291 RGD
G Pten phosphatase and tensin homolog GBrowse link IEA 1 236,771,027 236,837,261 RGD:1600115 Ensembl
G Wnt1 wingless-type MMTV integration site family, member 1 GBrowse link IEA 7 137,557,836 137,561,883 RGD:1600115 Ensembl
G Wnt1 wingless-type MMTV integration site family, member 1 GBrowse link ISO 7 137,557,836 137,561,883 RGD:1624291 RGD
negative regulation of cellular senescence term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Bcl2l12 BCL2-like 12 (proline rich) GBrowse link ISO 1 95,462,429 95,471,148 RGD:1624291 RGD
G Cdk6 cyclin-dependent kinase 6 GBrowse link ISO 4 27,362,656 27,618,006 RGD:1624291 RGD
G Cdk6 cyclin-dependent kinase 6 GBrowse link IEA 4 27,362,656 27,618,006 RGD:1600115 Ensembl
G Sirt1 sirtuin 1 GBrowse link IEA 20 25,675,302 25,686,494 RGD:1600115 Ensembl
G Sirt1 sirtuin 1 GBrowse link ISO 20 25,675,302 25,686,494 RGD:1624291 RGD
G Twist1 twist family bHLH transcription factor 1 GBrowse link ISO 6 52,605,869 52,607,863 RGD:1624291 RGD
G Twist1 twist family bHLH transcription factor 1 GBrowse link IEA 6 52,605,869 52,607,863 RGD:1600115 Ensembl
nucleolar fragmentation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Zfp354a zinc finger protein 354A GBrowse link IMP 10 36,654,406 36,665,659 RGD:1303369 RGD
oncogene-induced cell senescence term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Hmga1 high mobility group AT-hook 1 GBrowse link ISS 20 5,769,052 5,772,269 RGD:1600115 UniProt
G Hmga1 high mobility group AT-hook 1 GBrowse link ISO 20 5,769,052 5,772,269 RGD:1624291 RGD
G Hmga2 high mobility group AT-hook 2 GBrowse link ISO 7 59,638,555 59,753,791 RGD:1624291 RGD
G Hmga2 high mobility group AT-hook 2 GBrowse link ISS 7 59,638,555 59,753,791 RGD:1600115 UniProt
organ senescence term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ctgf connective tissue growth factor GBrowse link IEP 1 21,327,099 21,330,215 RGD:2314657 RGD
G Pdx1 pancreatic and duodenal homeobox 1 IEP RGD:2311175 RGD
oxidative stress-induced premature senescence term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Arntl aryl hydrocarbon receptor nuclear translocator-like GBrowse link ISS 1 171,062,181 171,162,426 RGD:1600115 UniProt
G LOC100910954 cellular tumor antigen p53-like IEA RGD:1600115 Ensembl
G Pla2r1 phospholipase A2 receptor 1 GBrowse link ISO 3 42,121,966 42,250,869 RGD:1624291 RGD
G Pla2r1 phospholipase A2 receptor 1 GBrowse link ISS 3 42,121,966 42,250,869 RGD:1600115 UniProt
G Tp53 tumor protein p53 GBrowse link ISO 10 56,399,721 56,411,150 RGD:1624291 RGD
G Wnt16 wingless-type MMTV integration site family, member 16 GBrowse link IEA 4 48,609,677 48,620,317 RGD:1600115 Ensembl
G Wnt16 wingless-type MMTV integration site family, member 16 GBrowse link ISO 4 48,609,677 48,620,317 RGD:1624291 RGD
positive regulation of cell aging term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Lmna lamin A/C GBrowse link ISO 2 180,595,724 180,616,354 RGD:1624291 RGD
G Lmna lamin A/C GBrowse link IEA 2 180,595,724 180,616,354 RGD:1600115 Ensembl
G Lmna lamin A/C GBrowse link ISS 2 180,595,724 180,616,354 RGD:1600115 UniProt
G Tp53 tumor protein p53 GBrowse link ISO 10 56,399,721 56,411,150 RGD:1624291 RGD
positive regulation of cellular senescence term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link ISO 5 108,908,749 108,916,380 RGD:1624291 RGD
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link IEA 5 108,908,749 108,916,380 RGD:1600115 Ensembl
G Hmga1 high mobility group AT-hook 1 GBrowse link ISS 20 5,769,052 5,772,269 RGD:1600115 UniProt
G Hmga1 high mobility group AT-hook 1 GBrowse link ISO 20 5,769,052 5,772,269 RGD:1624291 RGD
G Hmga2 high mobility group AT-hook 2 GBrowse link ISO 7 59,638,555 59,753,791 RGD:1624291 RGD
G Hmga2 high mobility group AT-hook 2 GBrowse link ISS 7 59,638,555 59,753,791 RGD:1600115 UniProt
G Sirt1 sirtuin 1 GBrowse link IEA 20 25,675,302 25,686,494 RGD:1600115 Ensembl
G Sirt1 sirtuin 1 GBrowse link ISO 20 25,675,302 25,686,494 RGD:1624291 RGD
regulation of cellular senescence term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Arntl aryl hydrocarbon receptor nuclear translocator-like GBrowse link ISS 1 171,062,181 171,162,426 RGD:1600115 UniProt
G Nuak1 NUAK family, SNF1-like kinase, 1 GBrowse link IEA 7 21,461,413 21,529,068 RGD:1600115 Ensembl
G Nuak1 NUAK family, SNF1-like kinase, 1 GBrowse link ISO 7 21,461,413 21,529,068 RGD:1624291 RGD
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 GBrowse link IEA 14 110,130,417 110,161,762 RGD:1600115 Ensembl
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 GBrowse link ISO 14 110,130,417 110,161,762 RGD:1624291 RGD
G Vash1 vasohibin 1 GBrowse link IEA 6 110,806,294 110,818,161 RGD:1600115 Ensembl
G Vash1 vasohibin 1 GBrowse link ISO 6 110,806,294 110,818,161 RGD:1624291 RGD
G Zfp277 zinc finger protein 277 ISO RGD:1624291 RGD
replicative cell aging term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 GBrowse link ISO 1 78,711,249 78,722,474 RGD:1624291 RGD
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 GBrowse link ISO 1 78,711,249 78,722,474 RGD:1624291 RGD
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 GBrowse link IEA 1 78,711,249 78,722,474 RGD:1600115 Ensembl
G Romo1 reactive oxygen species modulator 1 GBrowse link ISO 3 146,551,220 146,552,820 RGD:1624291 RGD
G Tmem115 transmembrane protein 115 GBrowse link IEP 8 112,781,304 112,786,168 RGD:2303064 RGD
G Tp63 tumor protein p63 GBrowse link IMP 11 76,900,622 77,200,251 RGD:1600401 RGD
G Wrn Werner syndrome, RecQ helicase-like GBrowse link ISO 16 62,535,144 62,668,700 RGD:1624291 RGD
G Wrn Werner syndrome, RecQ helicase-like GBrowse link IEA 16 62,535,144 62,668,700 RGD:1600115 Ensembl
replicative senescence term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Atm ataxia telangiectasia mutated GBrowse link ISO 8 56,894,746 56,996,565 RGD:1624291 RGD
G Atr ataxia telangiectasia and Rad3 related GBrowse link ISO 8 100,936,342 101,014,881 RGD:1624291 RGD
G Atr ataxia telangiectasia and Rad3 related GBrowse link IEA 8 100,936,342 101,014,881 RGD:1600115 Ensembl
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link ISO 5 108,908,749 108,916,380 RGD:1624291 RGD
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link IEA 5 108,908,749 108,916,380 RGD:1600115 Ensembl
G Ctc1 CTS telomere maintenance complex component 1 GBrowse link IEA 10 55,768,182 55,788,836 RGD:1600115 Ensembl
G Ctc1 CTS telomere maintenance complex component 1 GBrowse link ISO 10 55,768,182 55,788,836 RGD:1624291 RGD
G LOC100910954 cellular tumor antigen p53-like IEA RGD:1600115 Ensembl
G Mme membrane metallo-endopeptidase GBrowse link ISO 2 153,031,724 153,114,515 RGD:1624291 RGD
G Mme membrane metallo-endopeptidase GBrowse link ISS 2 153,031,724 153,114,515 RGD:1600115 UniProt
G Pla2r1 phospholipase A2 receptor 1 GBrowse link ISO 3 42,121,966 42,250,869 RGD:1624291 RGD
G Pla2r1 phospholipase A2 receptor 1 GBrowse link ISS 3 42,121,966 42,250,869 RGD:1600115 UniProt
G Tert telomerase reverse transcriptase GBrowse link ISO 1 30,445,180 30,465,942 RGD:1624291 RGD
G Tert telomerase reverse transcriptase GBrowse link IEA 1 30,445,180 30,465,942 RGD:1600115 Ensembl
G Tp53 tumor protein p53 GBrowse link ISO 10 56,399,721 56,411,150 RGD:1624291 RGD
G Wnt16 wingless-type MMTV integration site family, member 16 GBrowse link IEA 4 48,609,677 48,620,317 RGD:1600115 Ensembl
G Wnt16 wingless-type MMTV integration site family, member 16 GBrowse link ISO 4 48,609,677 48,620,317 RGD:1624291 RGD
stress-induced premature senescence term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Mapk14 mitogen activated protein kinase 14 GBrowse link ISO 20 6,939,249 7,000,378 RGD:1624291 RGD
G Mapk14 mitogen activated protein kinase 14 GBrowse link IEA 20 6,939,249 7,000,378 RGD:1600115 Ensembl
G Mapkapk5 mitogen-activated protein kinase-activated protein kinase 5 GBrowse link ISO 12 36,128,538 36,147,493 RGD:1624291 RGD
G Mapkapk5 mitogen-activated protein kinase-activated protein kinase 5 GBrowse link IEA 12 36,128,538 36,147,493 RGD:1600115 Ensembl
G Mapkapk5 mitogen-activated protein kinase-activated protein kinase 5 GBrowse link ISO 12 36,128,538 36,147,493 RGD:1624291 RGD
G Mapkapk5 mitogen-activated protein kinase-activated protein kinase 5 GBrowse link IEA 12 36,128,538 36,147,493 RGD:1600115 Ensembl

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 157111
    single-organism process 105227
      single-organism developmental process 33591
        aging 463
          age-dependent behavioral decline 0
          age-dependent general metabolic decline + 7
          cell aging + 173
          fruit ripening + 0
          multicellular organismal aging + 56
          organ senescence + 2
paths to the root