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Term:aging
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Accession:GO:0007568 term browser browse the term
Definition:A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700).
Synonyms:exact_synonym: ageing
 alt_id: GO:0016280
 xref_analog: Wikipedia:Aging


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aging term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme GBrowse link 10 95,361,338 95,381,455 RGD:6893473
G Ada adenosine deaminase GBrowse link 3 154,636,530 154,660,637 RGD:1624293
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide GBrowse link 2 235,952,313 235,970,671 RGD:5129089
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide GBrowse link 2 235,979,108 235,991,515 RGD:5129089
G Adm adrenomedullin GBrowse link 1 168,380,255 168,382,426 RGD:1625311
RGD:2325638
G Adra1a adrenoceptor alpha 1A GBrowse link 15 46,173,429 46,263,198 RGD:1625777
RGD:5688350
G Adra1d adrenoceptor alpha 1D GBrowse link 3 119,279,974 119,295,985 RGD:5688350
G Adrb1 adrenoceptor beta 1 GBrowse link 1 263,025,655 263,027,055 RGD:5129117
G Adrb2 adrenoceptor beta 2, surface GBrowse link 18 58,174,958 58,177,000 RGD:8548537
G Adrb3 adrenoceptor beta 3 GBrowse link 16 69,163,620 69,166,384 RGD:2313169
G Adrbk1 adrenergic, beta, receptor kinase 1 GBrowse link 1 206,873,002 206,892,868 RGD:1582266
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link 19 54,738,556 54,750,349 RGD:5129178
G Agtr1a angiotensin II receptor, type 1a GBrowse link 17 40,629,318 40,684,982 RGD:5129178
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link 6 137,640,482 137,657,552 RGD:5509106
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 GBrowse link 10 47,365,195 47,374,880 RGD:2300311
G Aldoc aldolase C, fructose-bisphosphate GBrowse link 10 64,308,826 64,312,415 RGD:2301137
G Alox12 arachidonate 12-lipoxygenase GBrowse link 10 57,080,603 57,092,874 RGD:2302179
G Amfr autocrine motility factor receptor, E3 ubiquitin protein ligase GBrowse link 19 11,434,553 11,467,592 RGD:1643424
G Amh anti-Mullerian hormone GBrowse link 7 10,417,325 10,419,673 RGD:2315641
G Aoc3 amine oxidase, copper containing 3 GBrowse link 10 90,357,094 90,365,040 RGD:2313935
G Apaf1 apoptotic peptidase activating factor 1 GBrowse link 7 27,932,908 28,020,533 RGD:2325740
G Apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 GBrowse link 15 26,904,124 26,906,224 RGD:2315679
G Apod apolipoprotein D RGD:2311181
G Apoe apolipoprotein E GBrowse link 1 79,003,634 79,006,387 RGD:2317724
G Aqp2 aquaporin 2 (collecting duct) GBrowse link 7 138,325,855 138,330,891 RGD:2313133
G Arg1 arginase 1 GBrowse link 1 20,998,894 21,011,275 RGD:8693646
G Asl argininosuccinate lyase GBrowse link 12 27,702,882 27,720,230 RGD:4140929
G Ass1 argininosuccinate synthase 1 GBrowse link 3 10,578,717 10,622,332 RGD:4140929
G Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 GBrowse link 7 36,493,661 36,600,280 RGD:2317748
G Atp5g3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) GBrowse link 3 56,511,747 56,514,204 RGD:2301244
G Atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 GBrowse link X 160,306,354 160,313,434 RGD:2301245
G Aurkb aurora kinase B GBrowse link 10 55,798,710 55,804,367 RGD:2315123
G Bak1 BCL2-antagonist/killer 1 GBrowse link 20 5,255,954 5,264,593 RGD:2316112
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link 13 12,730,736 12,905,108 RGD:2293079
G Bglap bone gamma-carboxyglutamate (gla) protein GBrowse link 2 180,482,313 180,483,290 RGD:6483558
G C1qb complement component 1, q subcomponent, B chain GBrowse link 5 155,647,524 155,653,074 RGD:1599511
G Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit GBrowse link 16 5,383,259 5,703,361 RGD:6906923
G Cacybp calcyclin binding protein GBrowse link 13 75,623,161 75,633,644 RGD:2326112
G Calca calcitonin-related polypeptide alpha GBrowse link 1 172,686,168 172,691,061 RGD:2314033
G Canx calnexin GBrowse link 10 35,850,944 35,883,494 RGD:2313153
G Capn10 calpain 10 RGD:2317923
G Casp12 caspase 12 GBrowse link 8 2,082,933 2,110,511 RGD:2311469
G Casp2 caspase 2 GBrowse link 4 70,029,728 70,047,164 RGD:4107079
G Casp7 caspase 7 GBrowse link 1 262,689,300 262,721,591 RGD:2311469
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link 5 160,704,234 160,721,796 RGD:2311469
G Cast calpastatin GBrowse link 2 1,495,048 1,608,477 RGD:5509820
G Cat catalase GBrowse link 3 88,654,077 88,686,212 RGD:5130205
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link 10 70,256,263 70,258,061 RGD:4891435
G Ccl5 chemokine (C-C motif) ligand 5 GBrowse link 10 71,605,791 71,610,330 RGD:2307163
G Ccr5 chemokine (C-C motif) receptor 5 GBrowse link 8 128,907,157 128,912,272 RGD:2307163
G Cd86 CD86 molecule GBrowse link 11 66,215,233 66,238,882 RGD:2313439
G Cdkn1c cyclin-dependent kinase inhibitor 1C GBrowse link 1 203,835,215 203,837,844 RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link 5 108,908,749 108,916,380 RGD:1358479
RGD:1624291
G Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) GBrowse link 5 108,939,669 108,945,293 RGD:7248759
G Ciita class II, major histocompatibility complex, transactivator GBrowse link 10 5,087,174 5,133,418 RGD:2313439
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase GBrowse link 10 89,519,421 89,525,978 RGD:6483356
G Cnr1 cannabinoid receptor 1 (brain) GBrowse link 5 50,427,173 50,445,471 RGD:2314647
G Col3a1 collagen, type III, alpha 1 GBrowse link 9 44,281,582 44,317,831 RGD:7257557
G Cp ceruloplasmin (ferroxidase) GBrowse link 2 105,086,278 105,135,367 RGD:1599628
G Crp C-reactive protein, pentraxin-related GBrowse link 13 88,702,243 88,703,153 RGD:6482314
G Cryab crystallin, alpha B GBrowse link 8 54,107,824 54,111,502 RGD:2303634
G Ctc1 CTS telomere maintenance complex component 1 GBrowse link 10 55,768,182 55,788,836 RGD:1624291
G Ctnna1 catenin (cadherin-associated protein), alpha 1, 102kDa GBrowse link 18 27,629,915 27,769,360 RGD:2289805
G Ctsc cathepsin C GBrowse link 1 144,629,802 144,661,183 RGD:1599647
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link 8 61,462,207 61,468,237 RGD:5147748
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 RGD:2307323
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 GBrowse link 1 81,345,425 81,359,415 RGD:2301454
G Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 GBrowse link 12 9,567,120 9,595,974 RGD:1625392
G Dcn decorin GBrowse link 7 35,004,234 35,045,191 RGD:2311426
G Ddit3 DNA-damage inducible transcript 3 GBrowse link 7 67,247,749 67,252,571 RGD:1299136
G Dld dihydrolipoamide dehydrogenase GBrowse link 6 49,185,188 49,205,894 RGD:2306416
G Dmd dystrophin GBrowse link X 71,501,362 71,671,414 RGD:6771366
G Ednra endothelin receptor type A GBrowse link 19 32,042,366 32,108,153 RGD:4892581
G Ednrb endothelin receptor type B GBrowse link 15 87,893,141 87,898,700 RGD:4892600
G Eif5a eukaryotic translation initiation factor 5A GBrowse link 10 56,760,289 56,764,689 RGD:2308860
G Eno3 enolase 3, beta, muscle GBrowse link 10 57,536,965 57,542,317 RGD:2301762
G Epo erythropoietin GBrowse link 12 19,551,768 19,555,208 RGD:2313640
G Ercc2 excision repair cross-complementation group 2 RGD:1600115
RGD:1624291
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link 2 218,371,050 218,382,645 RGD:2313773
G Fads1 fatty acid desaturase 1 GBrowse link 1 212,670,792 212,685,718 RGD:1625420
G Fas Fas cell surface death receptor GBrowse link 1 238,259,443 238,274,745 RGD:1600330
G Fgf2 fibroblast growth factor 2 GBrowse link 2 123,893,314 123,947,136 RGD:8655566
G Fos FBJ osteosarcoma oncogene GBrowse link 6 109,559,135 109,562,001 RGD:2293789
G Fosl2 fos-like antigen 2 RGD:2293789
G Foxg1 forkhead box G1 GBrowse link 6 69,217,672 69,220,482 RGD:2314183
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link 1 136,209,969 136,222,057 RGD:1582625
G Gfra1 GDNF family receptor alpha 1 GBrowse link 1 264,614,329 264,875,486 RGD:8693679
G Ggt1 gamma-glutamyltransferase 1 RGD:2315578
G Gjb6 gap junction protein, beta 6 GBrowse link 15 36,177,736 36,186,513 RGD:7364768
G Gnao1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O GBrowse link 19 11,472,083 11,623,600 RGD:2302009
G Gpx1 glutathione peroxidase 1 RGD:2306622
G Gpx4 glutathione peroxidase 4 GBrowse link 7 11,162,521 11,165,318 RGD:2306622
G Grb2 growth factor receptor bound protein 2 GBrowse link 10 105,722,014 105,818,649 RGD:1643178
G Gsn gelsolin GBrowse link 3 14,360,245 14,386,313 RGD:1304020
G Gss glutathione synthetase GBrowse link 3 146,057,517 146,087,820 RGD:2301454
G Gsta1 glutathione S-transferase alpha 1 GBrowse link 9 20,051,501 20,068,146 RGD:2306661
G Gsta2 glutathione S-transferase alpha 2 GBrowse link 8 83,299,249 83,312,958 RGD:2306661
G Gstm2 glutathione S-transferase mu 2 GBrowse link 2 203,549,022 203,553,380 RGD:2302179
G Hcn2 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 GBrowse link 7 11,485,257 11,503,614 RGD:2316624
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase GBrowse link 2 27,127,504 27,149,580 RGD:2317945
RGD:5508699
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled GBrowse link 15 55,463,743 55,532,293 RGD:1624378
G Ifi27l2b interferon, alpha-inducible protein 27 like 2B GBrowse link 6 127,733,540 127,735,026 RGD:1624291
G Igfbp2 insulin-like growth factor binding protein 2 GBrowse link 9 71,966,877 71,994,211 RGD:1626514
G Il10 interleukin 10 GBrowse link 13 43,953,900 43,957,766 RGD:7364992
G Il15 interleukin 15 GBrowse link 19 27,487,268 27,498,973 RGD:1626613
G Il1b interleukin 1 beta GBrowse link 3 116,964,422 116,970,867 RGD:1626647
G Il6 interleukin 6 GBrowse link 4 456,799 461,376 RGD:2306935
G Irak1 interleukin-1 receptor-associated kinase 1 GBrowse link X 159,960,184 159,969,180 RGD:7495793
G Ireb2 iron responsive element binding protein 2 GBrowse link 8 58,433,218 58,477,305 RGD:6893272
G Itgb2 integrin, beta 2 GBrowse link 20 11,446,521 11,485,009 RGD:6482194
G Jun jun proto-oncogene GBrowse link 5 115,358,166 115,361,259 RGD:2293789
G Jund jun D proto-oncogene GBrowse link 16 19,239,694 19,241,529 RGD:2293789
G Kcne2 potassium voltage-gated channel, Isk-related family, member 2 GBrowse link 11 32,277,711 32,290,828 RGD:7243962
G Kdr kinase insert domain receptor RGD:8549775
G Kl Klotho GBrowse link 12 3,732,712 3,772,371 RGD:633145
RGD:1624291
G Krt14 keratin 14 GBrowse link 10 89,144,357 89,148,415 RGD:1624291
G Krt16 keratin 16 GBrowse link 10 89,175,449 89,178,168 RGD:1624291
G Krt25 keratin 25 GBrowse link 10 88,217,581 88,224,858 RGD:1624291
G Krt33b keratin 33B GBrowse link 10 88,954,472 88,959,981 RGD:1624291
G Krt83 keratin 83 GBrowse link 7 140,178,781 140,185,794 RGD:1624291
G Krtap4-3 keratin associated protein 4-3 GBrowse link 10 88,787,902 88,788,468 RGD:1624291
G Krtap4-8 keratin associated protein 4-8 RGD:1624291
G Lck LCK proto-oncogene, Src family tyrosine kinase GBrowse link 5 148,707,505 148,718,296 RGD:1600226
G Ldlr low density lipoprotein receptor GBrowse link 8 20,824,040 20,846,920 RGD:1581819
G Litaf lipopolysaccharide-induced TNF factor GBrowse link 10 4,614,177 4,623,903 RGD:7247626
G LOC100362031 hypothetical protein LOC100362031 GBrowse link 10 88,620,297 88,621,034 RGD:1624291
G LOC691889 similar to ATPase, aminophospholipid transporter-like, class I, type 8A, member 2 GBrowse link 15 38,759,902 39,271,237 RGD:1600115
RGD:1624291
G Lonp1 lon peptidase 1, mitochondrial RGD:2303495
G Lrp1 low density lipoprotein receptor-related protein 1 GBrowse link 7 67,520,575 67,601,549 RGD:1625018
G Lrp2 low density lipoprotein receptor-related protein 2 GBrowse link 3 51,563,764 51,724,478 RGD:1641828
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 GBrowse link 7 11,553,219 11,556,621 RGD:2311548
G Mbp myelin basic protein GBrowse link 18 78,943,608 79,057,329 RGD:7327192
G Mgea5 meningioma expressed antigen 5 (hyaluronidase) GBrowse link 1 250,966,386 251,000,363 RGD:2305952
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link 20 13,191,986 13,192,851 RGD:1641992
G Mmp2 matrix metallopeptidase 2 GBrowse link 19 15,246,036 15,275,061 RGD:2290430
G Mmp9 matrix metallopeptidase 9 GBrowse link 3 155,985,473 155,993,433 RGD:2290430
G Mpo myeloperoxidase GBrowse link 10 76,085,872 76,097,012 RGD:2317972
G Msra methionine sulfoxide reductase A GBrowse link 15 43,509,775 43,756,283 RGD:70794
RGD:2324653
G Mt-atp6 mitochondrially encoded ATP synthase 6 GBrowse link MT 7,919 8,599 RGD:5490295
G Mt-co1 mitochondrially encoded cytochrome c oxidase I GBrowse link MT 5,323 6,867 RGD:2302303
G Mt-nd4 mitochondrially encoded NADH dehydrogenase 4 GBrowse link MT 10,160 11,537 RGD:2302306
G Nat1 N-acetyltransferase 1 (arylamine N-acetyltransferase) GBrowse link 16 23,855,555 23,876,531 RGD:5131598
G Ncam1 neural cell adhesion molecule 1 GBrowse link 8 52,822,350 53,120,572 RGD:2326009
G Ncf2 neutrophil cytosolic factor 2 GBrowse link 13 67,806,516 67,834,105 RGD:2292095
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 GBrowse link 1 251,521,559 251,527,815 RGD:2302396
G Ngf nerve growth factor (beta polypeptide) GBrowse link 2 197,621,726 197,632,960 RGD:8693644
G Nos1 nitric oxide synthase 1, neuronal GBrowse link 12 39,812,500 39,869,484 RGD:1642135
G Nos2 nitric oxide synthase 2, inducible GBrowse link 10 65,036,884 65,072,453 RGD:2313213
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link 4 6,158,847 6,179,441 RGD:2292095
G Nox4 NADPH oxidase 4 GBrowse link 1 143,415,816 143,603,554 RGD:2324660
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link 19 37,251,147 37,266,040 RGD:5133233
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 GBrowse link 18 32,371,496 32,459,145 RGD:4892124
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 GBrowse link 2 179,838,740 179,855,545 RGD:5684347
RGD:8693644
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 GBrowse link 17 11,494,463 11,811,654 RGD:5684924
G Ogg1 8-oxoguanine DNA glycosylase GBrowse link 4 149,209,745 149,219,081 RGD:8657133
RGD:8657381
G Opa1 optic atrophy 1 GBrowse link 11 73,005,470 73,058,136 RGD:7829729
G P2ry1 purinergic receptor P2Y, G-protein coupled, 1 GBrowse link 2 150,460,361 150,465,855 RGD:2316735
G P2ry2 purinergic receptor P2Y, G-protein coupled, 2 GBrowse link 1 158,440,018 158,454,213 RGD:2316735
G Pax2 paired box 2 GBrowse link 1 249,804,055 249,895,306 RGD:2316745
G Pde4d phosphodiesterase 4D, cAMP-specific GBrowse link 2 40,196,097 41,311,012 RGD:1624291
G Pebp1 phosphatidylethanolamine binding protein 1 GBrowse link 12 40,491,393 40,495,593 RGD:2302808
G Phox2a paired-like homeobox 2a GBrowse link 1 159,273,524 159,312,136 RGD:1579826
G Pik3r1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) GBrowse link 2 32,602,673 32,675,350 RGD:1625220
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) GBrowse link 13 64,135,729 64,280,815 RGD:1642464
G Polg polymerase (DNA directed), gamma GBrowse link 1 135,197,075 135,212,178 RGD:1600115
RGD:1624291
G Prkca protein kinase C, alpha GBrowse link 10 97,367,196 97,638,910 RGD:2298670
G Prkcd protein kinase C, delta GBrowse link 16 5,954,218 5,975,743 RGD:1642546
G Prkcq protein kinase C, theta GBrowse link 17 78,486,998 78,566,741 RGD:1625620
G Pten phosphatase and tensin homolog GBrowse link 1 236,771,027 236,837,261 RGD:2292534
G Ptgs1 prostaglandin-endoperoxide synthase 1 GBrowse link 3 15,343,832 15,365,412 RGD:2300265
G Pth1r parathyroid hormone 1 receptor GBrowse link 8 115,099,763 115,119,362 RGD:1599981
G Rela v-rel avian reticuloendotheliosis viral oncogene homolog A GBrowse link 1 208,262,669 208,273,148 RGD:2298786
G Retn resistin GBrowse link 12 2,499,630 2,501,370 RGD:7207255
G Rnpep arginyl aminopeptidase (aminopeptidase B) GBrowse link 13 48,267,923 48,286,295 RGD:2325947
G Rpn2 ribophorin II GBrowse link 3 147,976,544 148,023,743 RGD:2325966
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 GBrowse link 10 76,657,024 76,698,088 RGD:1643019
G Rtn4 reticulon 4 GBrowse link 14 110,725,089 110,772,578 RGD:2314960
G Rxra retinoid X receptor alpha GBrowse link 3 6,605,782 6,689,224 RGD:1643118
G Scap SREBF chaperone GBrowse link 8 114,706,479 114,761,342 RGD:1581819
G Serpina7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 GBrowse link X 126,739,203 126,744,763 RGD:1600136
G Serpinf1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 GBrowse link 10 62,713,441 62,739,444 RGD:2312350
G Serping1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 GBrowse link 3 67,968,808 67,978,102 RGD:7247626
G Shc1 SHC (Src homology 2 domain containing) transforming protein 1 GBrowse link 2 181,616,581 181,628,144 RGD:1643178
G Si sucrase-isomaltase (alpha-glucosidase) GBrowse link 2 163,520,975 163,601,280 RGD:1625553
G Sin3a SIN3 transcription regulator family member A GBrowse link 8 60,832,595 60,884,764 RGD:2306468
G Sirt3 sirtuin 3 GBrowse link 1 201,021,391 201,043,756 RGD:8158103
G Slc18a2 solute carrier family 18 (vesicular monoamine transporter), member 2 GBrowse link 1 265,789,917 265,824,551 RGD:2317339
G Slc32a1 solute carrier family 32 (GABA vesicular transporter), member 1 GBrowse link 3 149,342,399 149,347,124 RGD:2324692
G Slc34a2 solute carrier family 34 (type II sodium/phosphate contransporter), member 2 GBrowse link 14 62,660,006 62,679,311 RGD:2311313
G Slc6a3 solute carrier family 6 (neurotransmitter transporter), member 3 GBrowse link 1 30,516,568 30,557,540 RGD:1625669
G Snca synuclein, alpha (non A4 component of amyloid precursor) GBrowse link 4 89,613,731 89,722,807 RGD:6218973
G Socs2 suppressor of cytokine signaling 2 GBrowse link 7 32,605,714 32,608,323 RGD:2298927
G Socs3 suppressor of cytokine signaling 3 GBrowse link 10 107,958,468 107,959,330 RGD:625538
G Sod1 superoxide dismutase 1, soluble GBrowse link 11 29,810,766 29,816,342 RGD:1624291
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link 1 41,862,997 41,870,327 RGD:1625691
G Srebf1 sterol regulatory element binding transcription factor 1 GBrowse link 10 46,461,684 46,483,646 RGD:1581819
G Srebf2 sterol regulatory element binding transcription factor 2 GBrowse link 7 120,522,511 120,580,212 RGD:1581819
G Srr serine racemase GBrowse link 10 62,217,481 62,234,831 RGD:2302214
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 GBrowse link 1 75,632,632 75,708,022 RGD:2317008
G Tacr3 tachykinin receptor 3 GBrowse link 2 232,309,015 232,404,964 RGD:2305954
G Tfrc transferrin receptor GBrowse link 11 69,976,258 69,998,098 RGD:2292027
G Tgfb1 transforming growth factor, beta 1 GBrowse link 1 80,894,705 80,911,020 RGD:2302033
G Tgfb2 transforming growth factor, beta 2 GBrowse link 13 102,718,703 102,818,768 RGD:2302033
G Tgfb3 transforming growth factor, beta 3 GBrowse link 6 110,173,443 110,195,215 RGD:2302033
G Tgfbr1 transforming growth factor, beta receptor 1 GBrowse link 5 63,976,868 64,034,058 RGD:2302033
G Tgfbr2 transforming growth factor, beta receptor 2 GBrowse link 8 120,593,595 120,680,453 RGD:2302033
G Timp1 TIMP metallopeptidase inhibitor 1 GBrowse link X 12,542,496 12,547,094 RGD:2290357
G Timp2 TIMP metallopeptidase inhibitor 2 GBrowse link 10 108,310,473 108,358,821 RGD:2290357
RGD:2290430
G Timp3 TIMP metallopeptidase inhibitor 3 GBrowse link 7 19,677,144 19,727,072 RGD:2290357
RGD:2290430
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b GBrowse link 5 163,666,541 163,697,484 RGD:7245943
G Top2a topoisomerase (DNA) II alpha GBrowse link 10 87,771,337 87,800,960 RGD:2315123
G Tp53 tumor protein p53 GBrowse link 10 56,399,721 56,411,150 RGD:2290558
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 GBrowse link 8 5,472,515 5,577,537 RGD:7247586
G Tspo translocator protein GBrowse link 7 121,597,084 121,599,342 RGD:2317163
G Tyms thymidylate synthetase GBrowse link 9 112,604,912 112,617,706 RGD:2317423
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) GBrowse link 1 157,925,514 157,928,222 RGD:7204432
G Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) GBrowse link 1 157,896,001 157,909,608 RGD:2313527
G Vcam1 vascular cell adhesion molecule 1 GBrowse link 2 212,277,654 212,297,376 RGD:2313112
G Vdr vitamin D (1,25- dihydroxyvitamin D3) receptor GBrowse link 7 136,567,614 136,617,280 RGD:4889988
G Vegfa vascular endothelial growth factor A GBrowse link 9 10,520,730 10,536,071 RGD:8549775
G Vim vimentin GBrowse link 17 87,847,280 87,855,763 RGD:6480444
age-dependent response to oxidative stress term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Cln8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) GBrowse link 16 79,569,745 79,579,636 RGD:1600115
RGD:1624291
G Coq7 coenzyme Q7 homolog, ubiquinone (yeast) GBrowse link 1 176,722,271 176,746,436 RGD:1600115
RGD:1624291
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link 1 41,862,997 41,870,327 RGD:1624291
age-dependent response to reactive oxygen species term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link 1 41,862,997 41,870,327 RGD:1600115
RGD:1624291
age-dependent telomere shortening term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Terf1 telomeric repeat binding factor (NIMA-interacting) 1 GBrowse link 5 2,556,918 2,586,086 RGD:1600115
RGD:1624291
cell aging term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link 13 12,730,736 12,905,108 RGD:1600115
RGD:1624291
G Bglap bone gamma-carboxyglutamate (gla) protein GBrowse link 2 180,482,313 180,483,290 RGD:2316145
G Brca2 breast cancer 2, early onset GBrowse link 12 4,282,952 4,323,693 RGD:1600115
RGD:1624291
G Cdk1 cyclin-dependent kinase 1 GBrowse link 20 20,018,044 20,044,030 RGD:2301352
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link 5 108,908,749 108,916,380 RGD:1624291
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 GBrowse link 1 12,721,500 12,723,943 RGD:5147849
G Dnaja3 DnaJ (Hsp40) homolog, subfamily A, member 3 GBrowse link 10 10,984,721 11,009,374 RGD:1600115
RGD:1624291
G Hras Harvey rat sarcoma virus oncogene GBrowse link 1 201,385,705 201,388,987 RGD:1624291
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 GBrowse link X 41,489,343 41,491,788 RGD:2302236
G Htt huntingtin GBrowse link 14 81,490,322 81,636,856 RGD:1600115
RGD:1624291
G Icam1 intercellular adhesion molecule 1 GBrowse link 8 20,040,177 20,051,939 RGD:4145420
G Ilk integrin-linked kinase GBrowse link 1 163,481,299 163,487,550 RGD:2301768
G Met MET proto-oncogene, receptor tyrosine kinase GBrowse link 4 43,134,183 43,211,355 RGD:2317463
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link 20 13,191,986 13,192,851 RGD:1624291
G Mnt MAX network transcriptional repressor GBrowse link 10 62,146,582 62,161,832 RGD:1600115
RGD:1624291
G Morc3 MORC family CW-type zinc finger 3 GBrowse link 11 34,061,754 34,104,508 RGD:1600115
RGD:1624291
G Nox4 NADPH oxidase 4 GBrowse link 1 143,415,816 143,603,554 RGD:1600115
RGD:1624291
G Npm1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) GBrowse link 10 18,051,990 18,062,714 RGD:1600115
RGD:1624291
G Nup62 nucleoporin 62 GBrowse link 1 95,288,019 95,303,545 RGD:1600115
RGD:1624291
G Pdcd4 programmed cell death 4 GBrowse link 1 260,183,648 260,202,032 RGD:1600115
RGD:1624291
G Pml promyelocytic leukemia GBrowse link 8 62,020,438 62,051,927 RGD:1624291
G Pot1b protection of telomeres 1B RGD:1600115
G Prelp proline/arginine-rich end leucine-rich repeat protein GBrowse link 13 46,863,392 46,874,172 RGD:1600115
RGD:1624291
G Sod1 superoxide dismutase 1, soluble GBrowse link 11 29,810,766 29,816,342 RGD:1600115
RGD:1624291
G Tbx2 T-box 2 GBrowse link 10 74,085,203 74,092,988 RGD:1624291
G Tbx3 T-box 3 GBrowse link 12 38,155,494 38,166,670 RGD:1600115
RGD:1624291
G Tp53 tumor protein p53 GBrowse link 10 56,399,721 56,411,150 RGD:1600115
RGD:1624291
G Tp63 tumor protein p63 GBrowse link 11 76,900,622 77,200,251 RGD:1624291
G Wrn Werner syndrome, RecQ helicase-like GBrowse link 16 62,535,144 62,668,700 RGD:1624291
G Zmiz1 zinc finger, MIZ-type containing 1 GBrowse link 16 1,037,882 1,245,259 RGD:1600115
RGD:1624291
cellular senescence term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Calr calreticulin GBrowse link 19 24,964,775 24,969,670 RGD:1600115
RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link 20 7,376,325 7,386,778 RGD:1600115
RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link 5 108,908,749 108,916,380 RGD:1624291
G Hras Harvey rat sarcoma virus oncogene GBrowse link 1 201,385,705 201,388,987 RGD:1600115
RGD:1624291
G Id2 inhibitor of DNA binding 2 GBrowse link 6 42,781,476 42,783,307 RGD:1600115
RGD:1624291
G Kat6a K(lysine) acetyltransferase 6A GBrowse link 16 73,553,868 73,634,794 RGD:1600115
RGD:1624291
G Map2k1 mitogen activated protein kinase kinase 1 GBrowse link 8 68,379,074 68,451,554 RGD:1600115
RGD:1624291
G Nsmce2 non-SMC element 2, MMS21 homolog (S. cerevisiae) GBrowse link 7 96,167,635 96,393,594 RGD:1600115
RGD:1624291
G Opa1 optic atrophy 1 GBrowse link 11 73,005,470 73,058,136 RGD:1600115
RGD:1624291
G Pml promyelocytic leukemia GBrowse link 8 62,020,438 62,051,927 RGD:1600115
RGD:1624291
G Prkcd protein kinase C, delta GBrowse link 16 5,954,218 5,975,743 RGD:1624291
G RGD1305645 similar to RIKEN cDNA 1500015O10 GBrowse link 9 42,931,051 42,950,605 RGD:1600115
RGD:1624291
G Smc5 structural maintenance of chromosomes 5 GBrowse link 1 226,494,137 226,566,143 RGD:1600115
RGD:1624291
G Smc6 structural maintenance of chromosomes 6 GBrowse link 6 34,710,177 34,763,158 RGD:1600115
RGD:1624291
G Srf serum response factor (c-fos serum response element-binding transcription factor) GBrowse link 9 9,788,378 9,797,639 RGD:1600115
RGD:1624291
G Tbx2 T-box 2 GBrowse link 10 74,085,203 74,092,988 RGD:1600115
RGD:1624291
G Tbx3 T-box 3 GBrowse link 12 38,155,494 38,166,670 RGD:1600115
RGD:1624291
chronological cell aging term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Eng endoglin RGD:1600115
RGD:1624291
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link 12 20,931,996 20,942,374 RGD:1600115
RGD:1624291
determination of adult lifespan term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Bbc3 Bcl-2 binding component 3 RGD:1600115
G Coq7 coenzyme Q7 homolog, ubiquinone (yeast) GBrowse link 1 176,722,271 176,746,436 RGD:1600115
RGD:1624291
G Ercc5 excision repair cross-complementation group 5 GBrowse link 9 43,248,023 43,293,196 RGD:1600115
RGD:1624291
G Ghrhr growth hormone releasing hormone receptor GBrowse link 4 84,135,530 84,148,503 RGD:1600115
RGD:1624291
G Htt huntingtin GBrowse link 14 81,490,322 81,636,856 RGD:1600115
RGD:1624291
G Ide insulin degrading enzyme GBrowse link 1 241,547,869 241,646,052 RGD:1600115
RGD:1624291
G Inpp5d inositol polyphosphate-5-phosphatase D GBrowse link 9 86,576,742 86,682,240 RGD:1600115
RGD:1624291
G Lrrk2 leucine-rich repeat kinase 2 GBrowse link 7 130,105,902 130,267,747 RGD:1600115
RGD:1624291
G Msh2 mutS homolog 2 GBrowse link 6 11,199,906 11,258,350 RGD:1600115
RGD:1624291
G Msh6 mutS homolog 6 GBrowse link 6 11,525,292 11,542,592 RGD:1600115
RGD:1624291
G Pou1f1 POU class 1 homeobox 1 GBrowse link 11 2,959,383 2,980,545 RGD:1600115
RGD:1624291
G Tfcp2l1 transcription factor CP2-like 1 GBrowse link 13 31,288,228 31,401,482 RGD:1600115
RGD:1624291
G Tp53 tumor protein p53 GBrowse link 10 56,399,721 56,411,150 RGD:1624291
multicellular organismal aging term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Acan aggrecan GBrowse link 1 134,787,341 134,848,992 RGD:2315752
G Adrbk2 adrenergic, beta, receptor kinase 2 RGD:5685607
G Cisd2 CDGSH iron sulfur domain 2 GBrowse link 2 232,902,533 232,927,338 RGD:1600115
RGD:1624291
G Ctsl cathepsin L GBrowse link 17 6,288,013 6,294,174 RGD:2315581
G Dbh dopamine beta-hydroxylase (dopamine beta-monooxygenase) GBrowse link 3 6,052,706 6,069,826 RGD:5129682
G Ddc dopa decarboxylase (aromatic L-amino acid decarboxylase) GBrowse link 14 92,698,636 92,788,635 RGD:5129108
G Edn1 endothelin 1 GBrowse link 17 28,303,886 28,309,775 RGD:4144863
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 GBrowse link 1 78,711,249 78,722,474 RGD:1600115
RGD:1624291
G Helt helt bHLH transcription factor GBrowse link 16 49,271,310 49,273,233 RGD:1600115
RGD:1624291
G Hyal2 hyaluronoglucosaminidase 2 GBrowse link 8 112,817,001 112,820,693 RGD:1600115
RGD:1624291
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 GBrowse link 3 18,498,913 18,519,738 RGD:1600115
RGD:1624291
G Rnf165 ring finger protein 165 GBrowse link 18 74,413,654 74,530,319 RGD:1624291
G Sec63 SEC63 homolog (S. cerevisiae) GBrowse link 20 46,669,125 46,738,077 RGD:1600115
RGD:1624291
G Serp1 stress-associated endoplasmic reticulum protein 1 GBrowse link 2 147,866,072 147,870,096 RGD:1600115
RGD:1624291
G Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 GBrowse link 3 87,870,558 87,992,401 RGD:1624291
G Spef2 sperm flagellar 2 GBrowse link 2 59,163,063 59,333,207 RGD:1624291
G Th tyrosine hydroxylase GBrowse link 1 203,164,253 203,171,506 RGD:5129108
G Tp63 tumor protein p63 GBrowse link 11 76,900,622 77,200,251 RGD:1600115
RGD:1624291
G Wrn Werner syndrome, RecQ helicase-like GBrowse link 16 62,535,144 62,668,700 RGD:1600115
RGD:1624291
negative regulation of cell aging term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Foxm1 forkhead box M1 GBrowse link 4 165,383,666 165,394,688 RGD:1600115
RGD:1624291
G Fzr1 fizzy/cell division cycle 20 related 1 (Drosophila) GBrowse link 7 9,816,491 9,829,006 RGD:1600115
RGD:1624291
G March5 membrane-associated ring finger (C3HC4) 5 GBrowse link 1 241,475,394 241,495,500 RGD:1600115
RGD:1624291
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link 20 13,191,986 13,192,851 RGD:1624291
G Pten phosphatase and tensin homolog GBrowse link 1 236,771,027 236,837,261 RGD:1600115
RGD:1624291
G Wnt1 wingless-type MMTV integration site family, member 1 GBrowse link 7 137,557,836 137,561,883 RGD:1600115
RGD:1624291
negative regulation of cellular senescence term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Bcl2l12 BCL2-like 12 (proline rich) GBrowse link 1 95,462,429 95,471,148 RGD:1624291
G Cdk6 cyclin-dependent kinase 6 GBrowse link 4 27,362,656 27,618,006 RGD:1600115
RGD:1624291
G Sirt1 sirtuin 1 GBrowse link 20 25,675,302 25,686,494 RGD:1600115
RGD:1624291
G Tp63 tumor protein p63 GBrowse link 11 76,900,622 77,200,251 RGD:1624291
G Twist1 twist family bHLH transcription factor 1 GBrowse link 6 52,605,869 52,607,863 RGD:1600115
RGD:1624291
nucleolar fragmentation term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Zfp354a zinc finger protein 354A GBrowse link 10 36,654,406 36,665,659 RGD:1303369
oncogene-induced cell senescence term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Hmga1 high mobility group AT-hook 1 GBrowse link 20 5,769,052 5,772,269 RGD:1600115
RGD:1624291
G Hmga2 high mobility group AT-hook 2 GBrowse link 7 59,638,555 59,753,791 RGD:1600115
RGD:1624291
organ senescence term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ctgf connective tissue growth factor GBrowse link 1 21,327,099 21,330,215 RGD:2314657
G Pdx1 pancreatic and duodenal homeobox 1 RGD:2311175
oxidative stress-induced premature senescence term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Arntl aryl hydrocarbon receptor nuclear translocator-like GBrowse link 1 171,062,181 171,162,426 RGD:1600115
RGD:1624291
G LOC100910954 cellular tumor antigen p53-like RGD:1600115
G Pla2r1 phospholipase A2 receptor 1 GBrowse link 3 42,121,966 42,250,869 RGD:1600115
RGD:1624291
G Tp53 tumor protein p53 GBrowse link 10 56,399,721 56,411,150 RGD:1624291
G Wnt16 wingless-type MMTV integration site family, member 16 GBrowse link 4 48,609,677 48,620,317 RGD:1600115
RGD:1624291
positive regulation of cell aging term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Lmna lamin A/C GBrowse link 2 180,595,724 180,616,354 RGD:1600115
RGD:1624291
G Tp53 tumor protein p53 GBrowse link 10 56,399,721 56,411,150 RGD:1624291
positive regulation of cellular senescence term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link 5 108,908,749 108,916,380 RGD:1600115
RGD:1624291
G Hmga1 high mobility group AT-hook 1 GBrowse link 20 5,769,052 5,772,269 RGD:1600115
RGD:1624291
G Hmga2 high mobility group AT-hook 2 GBrowse link 7 59,638,555 59,753,791 RGD:1600115
RGD:1624291
G Sirt1 sirtuin 1 GBrowse link 20 25,675,302 25,686,494 RGD:1600115
RGD:1624291
regulation of cellular senescence term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Arntl aryl hydrocarbon receptor nuclear translocator-like GBrowse link 1 171,062,181 171,162,426 RGD:1600115
RGD:1624291
G Nuak1 NUAK family, SNF1-like kinase, 1 GBrowse link 7 21,461,413 21,529,068 RGD:1600115
RGD:1624291
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 GBrowse link 14 110,130,417 110,161,762 RGD:1600115
RGD:1624291
G Vash1 vasohibin 1 GBrowse link 6 110,806,294 110,818,161 RGD:1600115
RGD:1624291
G Zfp277 zinc finger protein 277 RGD:1624291
replicative cell aging term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 GBrowse link 1 78,711,249 78,722,474 RGD:1600115
RGD:1624291
G Romo1 reactive oxygen species modulator 1 GBrowse link 3 146,551,220 146,552,820 RGD:1624291
G Tmem115 transmembrane protein 115 GBrowse link 8 112,781,304 112,786,168 RGD:2303064
G Tp63 tumor protein p63 GBrowse link 11 76,900,622 77,200,251 RGD:1600401
G Wrn Werner syndrome, RecQ helicase-like GBrowse link 16 62,535,144 62,668,700 RGD:1600115
RGD:1624291
replicative senescence term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase GBrowse link 8 56,894,746 56,996,565 RGD:1600115
RGD:1624291
G Atr ATR serine/threonine kinase GBrowse link 8 100,936,342 101,014,881 RGD:1600115
RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link 5 108,908,749 108,916,380 RGD:1600115
RGD:1624291
G Ctc1 CTS telomere maintenance complex component 1 GBrowse link 10 55,768,182 55,788,836 RGD:1600115
RGD:1624291
G LOC100910954 cellular tumor antigen p53-like RGD:1600115
G Mme membrane metallo-endopeptidase GBrowse link 2 153,031,724 153,114,515 RGD:1600115
RGD:1624291
G Pla2r1 phospholipase A2 receptor 1 GBrowse link 3 42,121,966 42,250,869 RGD:1600115
RGD:1624291
G Tert telomerase reverse transcriptase GBrowse link 1 30,445,180 30,465,942 RGD:1600115
RGD:1624291
G Tp53 tumor protein p53 GBrowse link 10 56,399,721 56,411,150 RGD:1624291
G Wnt16 wingless-type MMTV integration site family, member 16 GBrowse link 4 48,609,677 48,620,317 RGD:1600115
RGD:1624291
stress-induced premature senescence term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Mapk14 mitogen activated protein kinase 14 GBrowse link 20 6,939,249 7,000,378 RGD:1600115
RGD:1624291
G Mapkapk5 mitogen-activated protein kinase-activated protein kinase 5 GBrowse link 12 36,128,538 36,147,493 RGD:1600115
RGD:1624291

Term paths to the root
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  biological_process 171926
    single-organism process 112829
      single-organism developmental process 34124
        aging 479
          age-dependent behavioral decline 0
          age-dependent general metabolic decline + 7
          cell aging + 177
          fruit ripening + 0
          multicellular organismal aging + 56
          organ senescence + 2
paths to the root