ONTOLOGY REPORT - ANNOTATIONS


Term:toluene 2,4-diisocyanate
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Accession:CHEBI:53556 term browser browse the term
Definition:A toluene meta-diisocyanate in which the isocyanato groups are at positions 2 and 4 relative to the methyl group on the benzene ring.
Synonyms:exact_synonym: 2,4-diisocyanato-1-methylbenzene
 related_synonym: 2,4-Diisocyanatotoluene;   2,4-TDI;   4-Methyl-m-phenylene diisocyanate;   C9H6N2O2;   Cc1ccc(cc1N=C=O)N=C=O;   InChI=1S/C9H6N2O2/c1-7-2-3-8(10-5-12)4-9(7)11-6-13/h2-4H,1H3;   InChIKey=DVKJHBMWWAPEIU-UHFFFAOYSA-N;   Isocyanic acid, 4-methyl-m-phenylene ester;   TDI;   Toluylene-2,4-diisocyanate;   Tolylene-2,4-diisocyanate;   toluene-2,4-diyl diisocyanate
 xref_casrn: 584-84-9
 xref: Beilstein:744602 "Beilstein Registry Number";   ChemIDplus:584-84-9 "CAS Registry Number";   CiteXplore:17042142 "PubMed citation";   CiteXplore:19647056 "PubMed citation";   CiteXplore:21725071 "PubMed citation";   CiteXplore:21878336 "PubMed citation";   CiteXplore:22151392 "PubMed citation";   CiteXplore:22206939 "PubMed citation";   CiteXplore:22229538 "PubMed citation";   CiteXplore:24572447 "PubMed citation";   CiteXplore:6296214 "PubMed citation";   CiteXplore:9811173 "PubMed citation"
 xref_mesh: MESH:D014051
 xref: NIST Chemistry WebBook:584-84-9 "CAS Registry Number";   Reaxys:744602 "Reaxys Registry Number";   Wikipedia:Toluene_diisocyanate "Wikipedia"


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toluene 2,4-diisocyanate term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Acyp1 acylphosphatase 1, erythrocyte (common) type GBrowse link 6 109,320,444 109,327,303 RGD:6480464
G Adamts15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 GBrowse link 8 30,683,281 30,706,659 RGD:6480464
G Adcy6 adenylate cyclase 6 GBrowse link 7 137,339,933 137,360,020 RGD:6480464
G Alb albumin GBrowse link 14 19,126,935 19,142,214 RGD:6480464
G Ankrd2 ankyrin repeat domain 2 (stretch responsive muscle) GBrowse link 1 248,806,966 248,816,413 RGD:6480464
G Asns asparagine synthetase (glutamine-hydrolyzing) GBrowse link 4 32,758,866 32,776,220 RGD:6480464
G Axl Axl receptor tyrosine kinase GBrowse link 1 80,964,751 80,994,300 RGD:6480464
G Bpifa2 BPI fold containing family A, member 2 GBrowse link 3 144,395,541 144,403,499 RGD:6480464
G Bspry B-box and SPRY domain containing GBrowse link 5 79,471,061 79,493,239 RGD:6480464
G Bst2 bone marrow stromal cell antigen 2 GBrowse link 16 18,698,545 18,701,768 RGD:6480464
G Cacnb3 calcium channel, voltage-dependent, beta 3 subunit GBrowse link 7 137,384,752 137,394,283 RGD:6480464
G Ccl11 chemokine (C-C motif) ligand 11 GBrowse link 10 70,279,161 70,283,762 RGD:6480464
G Ccl12 chemokine (C-C motif) ligand 12 GBrowse link 10 70,321,036 70,322,586 RGD:6480464
G Ccl17 chemokine (C-C motif) ligand 17 GBrowse link 19 10,641,376 10,642,827 RGD:6480464
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link 10 70,256,263 70,258,061 RGD:6480464
G Ccl3 chemokine (C-C motif) ligand 3 GBrowse link 10 71,744,559 71,746,109 RGD:6480464
G Ccl4 chemokine (C-C motif) ligand 4 GBrowse link 10 71,759,643 71,761,115 RGD:6480464
G Ccl5 chemokine (C-C motif) ligand 5 GBrowse link 10 71,605,791 71,610,330 RGD:6480464
G Ccl6 chemokine (C-C motif) ligand 6 GBrowse link 10 71,660,623 71,665,255 RGD:6480464
G Ccl7 chemokine (C-C motif) ligand 7 GBrowse link 10 70,267,281 70,269,131 RGD:6480464
G Ccl9 chemokine (C-C motif) ligand 9 GBrowse link 10 71,645,931 71,650,814 RGD:6480464
G Ccnf cyclin F GBrowse link 10 13,474,659 13,500,979 RGD:6480464
G Ccr5 chemokine (C-C motif) receptor 5 GBrowse link 8 128,907,157 128,912,272 RGD:6480464
G Cd4 Cd4 molecule GBrowse link 4 160,988,512 161,014,038 RGD:6480464
G Cd40 CD40 molecule, TNF receptor superfamily member 5 GBrowse link 3 156,092,602 156,107,427 RGD:6480464
G Cd47 Cd47 molecule GBrowse link 11 52,098,355 52,158,169 RGD:6480464
G Cdca2 cell division cycle associated 2 GBrowse link 15 47,225,711 47,271,412 RGD:6480464
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) GBrowse link 10 39,665,850 39,667,831 RGD:6480464
G Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) GBrowse link 7 116,227,239 116,271,993 RGD:6480464
G Csf3r colony stimulating factor 3 receptor (granulocyte) GBrowse link 5 145,374,596 145,394,045 RGD:6480464
G Cxcl1 chemokine (C-X-C motif) ligand 1 GBrowse link 14 18,690,339 18,692,118 RGD:6480464
G Cxcl10 chemokine (C-X-C motif) ligand 10 GBrowse link 14 17,265,986 17,268,183 RGD:6480464
G Cxcl16 chemokine (C-X-C motif) ligand 16 GBrowse link 10 57,296,126 57,300,721 RGD:6480464
G Cxcl3 chemokine (C-X-C motif) ligand 3 GBrowse link 14 18,767,306 18,787,340 RGD:6480464
G Cxcl6 chemokine (C-X-C motif) ligand 6 GBrowse link 14 18,825,357 18,826,269 RGD:6480464
G Cxcl9 chemokine (C-X-C motif) ligand 9 GBrowse link 14 17,284,085 17,288,996 RGD:6480464
G Cxcr4 chemokine (C-X-C motif) receptor 4 GBrowse link 13 41,308,286 41,312,190 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link 8 61,462,207 61,468,237 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 GBrowse link 8 61,439,062 61,447,861 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 GBrowse link 1 81,266,828 81,290,471 RGD:6480464
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 GBrowse link 1 82,191,741 82,204,629 RGD:6480464
G Dact1 dishevelled-binding antagonist of beta-catenin 1 GBrowse link 6 93,402,304 93,411,668 RGD:6480464
G Dnajb6 DnaJ (Hsp40) homolog, subfamily B, member 6 GBrowse link 4 732,491 796,237 RGD:6480464
G Dusp4 dual specificity phosphatase 4 GBrowse link 16 61,109,626 61,119,981 RGD:6480464
G Dut deoxyuridine triphosphatase GBrowse link 3 112,551,434 112,562,434 RGD:6480464
G Egfr epidermal growth factor receptor GBrowse link 14 97,617,358 97,788,211 RGD:6480464
G Erbb2 v-erb-b2 avian erythroblastic leukemia viral oncogene 2 GBrowse link 10 87,219,157 87,242,919 RGD:6480464
G Erbb3 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 GBrowse link 7 1,858,057 1,877,353 RGD:6480464
G Erbb4 v-erb-b2 avian erythroblastic leukemia viral oncogene 4 GBrowse link 9 66,843,898 67,967,970 RGD:6480464
G Ercc6l excision repair cross-complementation group 6-like GBrowse link X 90,195,080 90,212,006 RGD:6480464
G Fabp1 fatty acid binding protein 1, liver GBrowse link 4 104,412,200 104,415,981 RGD:6480464
G Ffar2 free fatty acid receptor 2 GBrowse link 1 85,878,452 85,879,444 RGD:6480464
G Fus fused in sarcoma RNA binding protein GBrowse link 1 187,250,871 187,264,742 RGD:6480464
G Gstm1 glutathione S-transferase mu 1 GBrowse link 2 203,575,444 203,580,821 RGD:6480464
G Gstm2 glutathione S-transferase mu 2 GBrowse link 2 203,549,022 203,553,380 RGD:6480464
G Gstm3 glutathione S-transferase mu 3 GBrowse link 2 203,532,363 203,537,135 RGD:6480464
G Gstm6 glutathione S-transferase, mu 6 GBrowse link 2 203,504,228 203,509,002 RGD:6480464
G Gstm6l glutathione S-transferase, mu 6-like GBrowse link 2 203,468,919 203,474,026 RGD:6480464
G Gstm7 glutathione S-transferase, mu 7 GBrowse link 2 203,491,366 203,496,812 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 GBrowse link 1 206,627,398 206,629,866 RGD:6480464
G Gzma granzyme A GBrowse link 2 44,488,295 44,500,128 RGD:6480464
G Gzmb granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) GBrowse link 15 35,195,075 35,198,506 RGD:6480464
G Hdc histidine decarboxylase GBrowse link 3 114,119,316 114,138,107 RGD:6480464
G Hrh1 histamine receptor H 1 GBrowse link 4 150,431,239 150,432,699 RGD:6480464
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 GBrowse link 9 11,033,496 11,038,868 RGD:6480464
G Hspa4 heat shock protein 4 GBrowse link 10 38,705,629 38,749,058 RGD:6480464
G Icam1 intercellular adhesion molecule 1 GBrowse link 8 20,040,177 20,051,939 RGD:6480464
G Ifi27 interferon, alpha-inducible protein 27 GBrowse link 6 127,725,194 127,731,665 RGD:6480464
G Ifi27l2b interferon, alpha-inducible protein 27 like 2B GBrowse link 6 127,733,540 127,735,026 RGD:6480464
G Ifi44l interferon-induced protein 44-like RGD:6480464
G Ifit1 interferon-induced protein with tetratricopeptide repeats 1 GBrowse link 1 238,609,171 238,611,236 RGD:6480464
G Ifnb1 interferon beta 1, fibroblast GBrowse link 5 107,837,628 107,838,182 RGD:6480464
G Ifng interferon gamma GBrowse link 7 57,621,756 57,625,792 RGD:6480464
G Ifngr2 interferon gamma receptor 2 GBrowse link 11 31,508,721 31,526,993 RGD:6480464
G Il10 interleukin 10 GBrowse link 13 43,953,900 43,957,766 RGD:6480464
G Il12b interleukin 12B GBrowse link 10 29,558,955 29,568,331 RGD:6480464
G Il12rb1 interleukin 12 receptor, beta 1 GBrowse link 16 19,126,653 19,137,584 RGD:6480464
G Il13 interleukin 13 GBrowse link 10 39,093,512 39,096,069 RGD:6480464
G Il15 interleukin 15 GBrowse link 19 27,487,268 27,498,973 RGD:6480464
G Il17a interleukin 17A GBrowse link 9 19,454,979 19,458,467 RGD:6480464
G Il19 interleukin 19 GBrowse link 13 43,878,668 43,885,001 RGD:6480464
G Il1a interleukin 1 alpha GBrowse link 3 116,913,612 116,924,114 RGD:6480464
G Il1b interleukin 1 beta GBrowse link 3 116,964,422 116,970,867 RGD:6480464
G Il1rl1 interleukin 1 receptor-like 1 GBrowse link 9 39,577,879 39,624,781 RGD:6480464
G Il2 interleukin 2 GBrowse link 2 123,655,005 123,659,709 RGD:6480464
G Il24 interleukin 24 GBrowse link 13 43,831,510 43,836,908 RGD:6480464
G Il2rb interleukin 2 receptor, beta RGD:6480464
G Il3 interleukin 3 GBrowse link 10 39,684,691 39,687,041 RGD:6480464
G Il4 interleukin 4 GBrowse link 10 39,074,582 39,080,134 RGD:6480464
G Il4r interleukin 4 receptor GBrowse link 1 184,612,903 184,637,863 RGD:6480464
G Il5 interleukin 5 GBrowse link 10 39,177,786 39,180,657 RGD:6480464
G Il6 interleukin 6 GBrowse link 4 456,799 461,376 RGD:6480464
G Il7 interleukin 7 GBrowse link 2 96,356,083 96,399,796 RGD:6480464
G Il9 interleukin 9 GBrowse link 17 14,068,757 14,071,880 RGD:6480464
G Inhba inhibin beta-A GBrowse link 17 57,244,466 57,257,531 RGD:6480464
G Isg15 ISG15 ubiquitin-like modifier GBrowse link 5 173,034,479 173,035,766 RGD:6480464
G Ka11 type I keratin KA11 GBrowse link 10 89,167,849 89,170,728 RGD:6480464
G Krt14 keratin 14 GBrowse link 10 89,144,357 89,148,415 RGD:6480464
G Krt16 keratin 16 GBrowse link 10 89,175,449 89,178,168 RGD:6480464
G Krt17 keratin 17 GBrowse link 10 89,185,097 89,189,816 RGD:6480464
G Krt19 keratin 19 GBrowse link 10 89,080,953 89,085,670 RGD:6480464
G Krt42 keratin 42 GBrowse link 10 89,191,771 89,199,727 RGD:6480464
G LOC102546764 cx9C motif-containing protein 4-like RGD:6480464
G LOC497963 similar to Nitric oxide synthase, inducible (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) GBrowse link 10 65,107,204 65,125,832 RGD:6480464
G Lta lymphotoxin alpha GBrowse link 20 3,657,842 3,659,848 RGD:6480464
G Ltb lymphotoxin beta (TNF superfamily, member 3) GBrowse link 20 3,666,524 3,668,369 RGD:6480464
G Map3k7 mitogen activated protein kinase kinase kinase 7 GBrowse link 5 48,252,637 48,308,820 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 GBrowse link 11 85,968,732 86,030,387 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 GBrowse link 1 185,935,044 185,941,245 RGD:6480464
G Mmp9 matrix metallopeptidase 9 GBrowse link 3 155,985,473 155,993,433 RGD:6480464
G Mtcp1 mature T-cell proliferation 1 GBrowse link 18 108,513 109,372 RGD:6480464
G Mx2 myxovirus (influenza virus) resistance 2 GBrowse link 11 37,548,650 37,572,717 RGD:6480464
G Nat1 N-acetyltransferase 1 (arylamine N-acetyltransferase) GBrowse link 16 23,855,555 23,876,531 RGD:6480464
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) GBrowse link 16 23,845,894 23,876,528 RGD:6480464
G Nat3 N-acetyltransferase 3 GBrowse link 16 23,785,757 23,786,629 RGD:6480464
G Ndp Norrie disease (pseudoglioma) GBrowse link X 17,416,946 17,441,393 RGD:6480464
G Ngf nerve growth factor (beta polypeptide) GBrowse link 2 197,621,726 197,632,960 RGD:6480464
G Nos1 nitric oxide synthase 1, neuronal GBrowse link 12 39,812,500 39,869,484 RGD:6480464
G Nos2 nitric oxide synthase 2, inducible GBrowse link 10 65,036,884 65,072,453 RGD:6480464
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link 4 6,158,847 6,179,441 RGD:6480464
G Osm oncostatin M GBrowse link 14 84,857,232 84,860,082 RGD:6480464
G Pf4 platelet factor 4 GBrowse link 14 18,812,550 18,813,259 RGD:6480464
G Phf11 PHD finger protein 11 GBrowse link 15 38,443,971 38,477,944 RGD:6480464
G Ppa1 pyrophosphatase (inorganic) 1 GBrowse link 20 29,015,647 29,042,399 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link 4 151,492,220 151,617,331 RGD:6480464
G Ppbp pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) GBrowse link 14 18,816,434 18,817,238 RGD:6480464
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha GBrowse link 8 106,061,334 106,155,090 RGD:6480464
G Pten phosphatase and tensin homolog GBrowse link 1 236,771,027 236,837,261 RGD:6480464
G Rbl1 retinoblastoma-like 1 (p107) GBrowse link 3 147,734,622 147,796,630 RGD:6480464
G Rcc1 regulator of chromosome condensation 1 RGD:6480464
G Rcn1 reticulocalbin 1, EF-hand calcium binding domain GBrowse link 3 90,832,151 90,846,395 RGD:6480464
G Recql4 RecQ protein-like 4 GBrowse link 7 114,752,863 114,760,027 RGD:6480464
G Rela v-rel avian reticuloendotheliosis viral oncogene homolog A GBrowse link 1 208,262,669 208,273,148 RGD:6480464
G RGD1307603 similar to hypothetical protein MGC37914 GBrowse link 1 206,645,199 206,648,212 RGD:6480464
G Rhoa ras homolog family member A RGD:6480464
G RT1-Bb RT1 class II, locus Bb GBrowse link 20 4,730,559 4,736,201 RGD:6480464
G Rtp4 receptor (chemosensory) transporter protein 4 GBrowse link 11 79,433,553 79,445,410 RGD:6480464
G Sftpd surfactant protein D RGD:6480464
G Smad1 SMAD family member 1 GBrowse link 19 30,348,886 30,409,345 RGD:6480464
G Sqle squalene epoxidase GBrowse link 7 96,096,897 96,111,772 RGD:6480464
G Srsf7 serine/arginine-rich splicing factor 7 GBrowse link 6 3,101,772 3,104,433 RGD:6480464
G Sult1a1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 GBrowse link 1 185,829,205 185,832,725 RGD:6480464
G Tac1 tachykinin, precursor 1 GBrowse link 4 32,649,666 32,657,632 RGD:6480464
G Tfdp1 transcription factor Dp-1 GBrowse link 16 81,018,040 81,056,049 RGD:6480464
G Tfec transcription factor EC GBrowse link 4 42,422,172 42,495,654 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 GBrowse link 1 80,894,705 80,911,020 RGD:6480464
G Timp1 TIMP metallopeptidase inhibitor 1 GBrowse link X 12,542,496 12,547,094 RGD:6480464
G Tnf tumor necrosis factor GBrowse link 20 3,661,000 3,663,618 RGD:6480464
G Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a GBrowse link 10 12,940,334 12,942,343 RGD:6480464
G Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 RGD:6480464
G Tslp thymic stromal lymphopoietin GBrowse link 18 25,268,082 25,274,214 RGD:6480464
G Txn1 thioredoxin 1 GBrowse link 5 75,921,365 75,933,595 RGD:6480464
G Usp18 ubiquitin specific peptidase 18 GBrowse link 4 157,692,720 157,694,884 RGD:6480464
G Usp8 ubiquitin specific peptidase 8 GBrowse link 3 114,237,065 114,284,543 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 GBrowse link 2 212,277,654 212,297,376 RGD:6480464
G Vegfa vascular endothelial growth factor A GBrowse link 9 10,520,730 10,536,071 RGD:6480464
G Xcl1 chemokine (C motif) ligand 1 GBrowse link 13 80,691,195 80,694,638 RGD:6480464
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta GBrowse link 6 41,945,769 41,976,123 RGD:6480464
G Zbp1 Z-DNA binding protein 1 GBrowse link 3 164,078,444 164,088,795 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 782369
    role 764807
      biological role 762806
        hapten 4117
          toluene 2,4-diisocyanate 302
Path 2
Term Annotations click to browse term
  CHEBI ontology 782369
    subatomic particle 780131
      composite particle 780131
        hadron 780131
          baryon 780131
            nucleon 780131
              atomic nucleus 780131
                atom 780131
                  main group element atom 728845
                    p-block element atom 724938
                      carbon group element atom 633059
                        carbon atom 625109
                          organic molecular entity 625097
                            heteroorganic entity 519405
                              organochalcogen compound 377629
                                organooxygen compound 347652
                                  isocyanates 468
                                    diisocyanate 427
                                      toluene meta-diisocyanate 310
                                        toluene 2,4-diisocyanate 302
paths to the root